Localization of organic anion transport protein 2 in the apical region of rat retinal pigment epithelium

Investigative Ophthalmology and Visual Science

Volumn 43, Issue 2, 2002, Pages 510-514

  Gao, Bo ^a   Wenzel, Andreas ^a   Grimm, Christian ^a   Vavricka, Stephan R ^a   Benke, Dietmar ^a   Meier, Peter J ^a   Remè, Charlotte E ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DIGOXIN; ORGANIC ANION TRANSPORTER 2; RETINOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; BRAIN; CAPILLARY ENDOTHELIUM; CELL MEMBRANE; CHOROID PLEXUS; CONTROLLED STUDY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOREACTIVITY; MALE; MOLECULAR CLONING; NONHUMAN; OOCYTE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RETINA; WESTERN BLOTTING; XENOPUS LAEVIS;

ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; MALE; MICROSCOPY, CONFOCAL; MICROVILLI; OOCYTES; ORGANIC ANION TRANSPORT POLYPEPTIDE C; PIGMENT EPITHELIUM OF EYE; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RETINOIDS; XENOPUS LAEVIS;

EID: 0036154356     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Retinal age pigments generated by selfassembling lysosomotropic detergents
2. Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
3. Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular degeneration
4. Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin
5. Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells
6. Participation of the retinal pigment epithelium in the rod outer segment renewal process
7. Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration
8. Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice
9. Delayed dark-adaptation and lipofuscin accumulation in abcr± mice: Implications for involvement of ABCR in age-related macular degeneration
10. Hepatic transport of bile salts
11. Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver
12. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
13. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2
14. Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain
15. Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver
16. Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver
17. A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors
18. Prevalence of age-related maculopathy
19. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane
20. Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease
21. ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro: Implications for retinal disease
22. Transient expression of oatp organic anion transporter in mammalian cells: Identification of candidate substrates
23. Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver
24. The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide
25. Oatp2 mediates bidirectional organic solute transport: A role for intracellular glutathione
26. Organic anion transport across the choroid plexus
27. Selective retinal pigment epithelial cell lipid metabolism and remodeling conserves photoreceptor docosahexaenoic acid following phagocytosis
28. Characterization of a novel cationic drug transporter in human retinal pigment epithelial cells
29. Distribution of organic anion transporting polypeptide2 (oatp2) and oatp3 in rat retina