Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum

Oncogene

Volumn 30, Issue 47, 2011, Pages 4740-4749

  Tanori, M ^a   Pasquali, E ^b   Leonardi, S ^a   Giardullo, P ^b   Di Majo, V ^a   Taccioli, G ^c   Essers, J ^d   Kanaar, R ^d   Mullenders, L H ^e   Atkinson, M J ^f   Mancuso, M ^a   Saran, A ^a   Pazzaglia, S ^a  

^a ENEA C R CASACCIA   (Italy)

^b GUGLIELMO MARCONI UNIVERSITY   (Italy)

^c BOSTON UNIVERSITY   (United States)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^f INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

DNA PKcs; LOH; Medulloblastoma; Rad54; Radiation

Indexed keywords

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CANCER RISK; CARCINOGENESIS; CELL CYCLE REGULATION; CELL PROTECTION; CEREBELLUM; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE DISRUPTION; GENE REARRANGEMENT; GENETIC RISK; GENOMIC INSTABILITY; HETEROZYGOSITY; HOMOLOGOUS RECOMBINATION; IN VIVO STUDY; IONIZING RADIATION; MEDULLOBLASTOMA; MOUSE; NEURAL STEM CELL; NON HOMOLOGOUS END JOINING; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PTC1 GENE; RAD54 GENE;

ANIMALS; CEREBELLAR NEOPLASMS; DNA DAMAGE; DNA END-JOINING REPAIR; DNA HELICASES; DNA-ACTIVATED PROTEIN KINASE; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; LOSS OF HETEROZYGOSITY; MEDULLOBLASTOMA; MICE; NUCLEAR PROTEINS; RECEPTORS, CELL SURFACE; RISK;

MUS;

EID: 81855194029     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.178     Document Type: Article

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