Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response

Cancer Research

Volumn 68, Issue 22, 2008, Pages 9497-9502

  Holcomb, Valerie B ^a,f   Rodier, Francis ^b,c   Choi, Yongjun ^a   Busuttil, Rita A ^c   Vogel, Hannes ^d   Vijg, Jan ^b,e   Campisi, Judith ^b,c   Hasty, Paul ^a,g  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^d STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^g UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KU ANTIGEN; PROTEIN KU80; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHROMOSOME REARRANGEMENT; DNA DAMAGE; DNA REPAIR; EMBRYO; GENE DELETION; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TUMOR GROWTH;

ANIMALS; ANTIGENS, NUCLEAR; CHROMOSOME ABERRATIONS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA-BINDING PROTEINS; GENES, APC; INTESTINE, SMALL; MICE; MICE, INBRED C57BL; NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 56449084458     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-2085     Document Type: Article

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