Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency

European Journal of Pediatrics

Volumn 168, Issue 1, 2009, Pages 87-93

  Turul, Tuba ^a,b   Tezcan, Ilhan ^b   Artac, Hasibe ^c   De Bruin Versteeg, Sandra ^a   Barendregt, Barbara H ^d   Reisli, Ismail ^c   Sanal, Ozden ^b   Van Dongen, Jacques J M ^a   Van Der Burg, Mirjam ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b HACETTEPE UNIVERSITY   (Turkey)

^c SELCUK UNIVERSITY   (Turkey)

^d SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Severe combined immunodeficiency; T cell receptor signaling; T cells; ZAP70

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIPROTOZOAL AGENT; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; ISONIAZID; PROTEIN KINASE ZAP 70; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN;

ARTICLE; ATOPIC DERMATITIS; CASE REPORT; CAUSE OF DEATH; CLINICAL FEATURE; ECZEMA; EOSINOPHILIA; FEMALE; HUMAN; INFANT; MALE; OMENN SYNDROME; PRIORITY JOURNAL; SEVERE COMBINED IMMUNODEFICIENCY; SPLENOMEGALY; SUBCUTANEOUS NODULE; WHEEZING; ZAP70 DEFICIENCY;

ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD8; FAILURE TO THRIVE; FEMALE; GENETIC HETEROGENEITY; HUMANS; INFANT; LYMPHOPENIA; PEDIGREE; POINT MUTATION; RECEPTORS, ANTIGEN, T-CELL; SEVERE COMBINED IMMUNODEFICIENCY; SIGNAL TRANSDUCTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 57049172523     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-008-0718-x     Document Type: Article

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