Homozygosity for an allele encoding deacetylated foxo1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 12, 2011, Pages 2920-2928

  Tsuchiya, Kyoichiro ^a   Banks, Alexander S ^b   Liang, Chien Ping ^a   Tabas, Ira ^a   Tall, Alan R ^a   Accili, Domenico ^a  

^a Columbia University ^*  (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; diabetes mellitus; insulin resistance; lipids; macrophages

Indexed keywords

CHOLESTEROL; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR FACTOR KAPPA B PRECURSOR P105; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL PROTECTION; CONTROLLED STUDY; DEACETYLATION; EX VIVO STUDY; HOMOZYGOSITY; INFLAMMATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

ACETYLATION; ALLELES; ANIMALS; APOPTOSIS; CELLS, CULTURED; CHOLESTEROL; CYTOKINES; FORKHEAD TRANSCRIPTION FACTORS; HOMOZYGOTE; INFLAMMATION; MACROPHAGES, PERITONEAL; MICE; MODELS, ANIMAL; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 81755184109     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.219477     Document Type: Article

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