Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6

Journal of Physiology

Volumn 507, Issue 3, 1998, Pages 881-894

  Chapman, Victoria ^a   Suzuki, Rie ^a   Dickenson, Anthony H ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DENERVATION; ELECTROPHYSIOLOGY; EVOKED RESPONSE; HINDLIMB; HYPERALGESIA; LUMBAR SPINE; MALE; NERVE CELL; NERVE LIGATION; NONHUMAN; PERIPHERAL NERVE INJURY; PLASTICITY; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SOMATOSENSORY SYSTEM; SPINAL NERVE; AFFERENT NERVE GROUP 1; ANIMAL BEHAVIOR; HIND PAW; MECHANICAL STIMULATION; NERVE CELL PLASTICITY; NERVE FIBER C; NERVE INJURY; SPINAL CORD NERVE CELL; THERMAL STIMULATION; WITHDRAWAL REFLEX;

ACETONE; ANESTHESIA, GENERAL; ANIMALS; DENERVATION; ELECTROPHYSIOLOGY; FUNCTIONAL LATERALITY; HINDLIMB; MALE; NERVE FIBERS; NEURONAL PLASTICITY; NEURONS; PAIN; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; REFERENCE VALUES; SCIATIC NERVE; SPINAL CORD; SPINAL NERVES;

EID: 0032520875     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.881bs.x     Document Type: Article

References (41)

1. BASBAUM, A. I., GAUTRON, M., JAZAT, F., MAYES, M. & GUILBAUD, G. (1991). The spectrum of fiber loss in a model of neuropathic pain in the rat: an electron microscopic study. Pain 47, 359-367.
2. BENNETT, G. J. & XIE, Y.-K. (1988). A peripheral mononeuropathy in rat produces disorders of pain sensation like those seen in man. Pain 33, 87-109.
3. BESTER, H., MENENDEZ, L., BESSON, J. M. & BERNARD, J. F. (1995). Spino (trigemino) parabrachiohypothalamic pathway : electrophysiological evidence for an involvement in pain processes. Journal of Neurophysiology 73, 568-585.
4. BOWERSOX, S. S., GADBOIS, T., SINGH, T., PETTUS, M., WANG, Y.-X. & LUTHER, R. R. (1996). Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain. Journal of Pharmacology and Experimental Therapeutics 279, 1243-1249.
5. BURCHIEL, K. J. (1984). Effects of electrical and mechanical stimulation on two foci of spontaneous activity which develop in primary afferent neurons after peripheral axotomy. Pain 18, 249-265.
6. CARLTON, S. M., DOUGHERTY, P. M., POVER, C. M. & COGGESHALL, R. E. (1991). Neuroma formation and numbers of axons in a rat model of experimental peripheral neuropathy. Neuroscience Letters 131, 88-92.
7. CHAPLAN, S. R., MALMBERG, A. B. & YAKSH, T. L. (1997). Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. Journal of Pharmacology and Experimental Therapeutics 280, 829-838.
8. CHAPMAN, V. & DICKENSON, A. H. (1994). Enhanced responses of rat dorsal horn neurones after UV irradiation of the hindpaw; roles of the NMDA receptor. Neuroscience Letters 176, 41-44.
9. CHAPMAN, V., SUZUKI, R. & DICKENSON, A. H. (1997). Carbamazepine and gabapentin modulate aberrant spinal neuronal responses after chung neuropathy. Society for Neuroscience Abstracts 23(2), 1811.
10. DICKENSON, A. H. & SULLIVAN, A. F. (1990). Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat. Brain Research 506, 31-39.
11. DI PIERO, V., JONES, A. K. P., IANNOTTI, F., POWELL, M., PERANI, D., LENZI, G. L. & FRACKOWIAK, R. S. J. (1991). Chronic pain: a PET study of the central effects of percutaneous high cervical cordotomy. Pain 46, 9-12.
12. GUILBAUD, G. (1991). Neuronal responsivity at supra-spinal levels (ventraobasal thalamus complex and SM1 cortex) in a rat model of mononeuropathy. In Lesions of Primary Afferent Fibres as a Tool for the Study of Clinical Pain, ed. BESSON, J. M. & GUILBAUD, G., pp. 219-232. Elsevier Science Publishers B.V.
13. HWANG, J. H. & YAKSH, T. L. (1997). The effect of spinal GABA receptor agonists on tactile allodynia in a surgically induced neuropathic pain model in the rat. Pain 70, 15-22.
14. IADAROLA, M. J., MAX, M. B., BERMAN, K. F., BYAS-SMITH, M. G., COGHILL, R. C., GRACELY, R. H. & BENNETT, G. J. (1995). Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain. Pain 63, 55-64.
15. KAJANDER, K. C. & BENNETT, G. J. (1992). Onset of a painful peripheral neuropathy in rat: A partial and differential deafferentation and spontaneous discharge in Aβ and Aδ primary afferent neurons. Journal of Neurophysiology 68, 734-744.
16. KAJANDER, K. C., WAKISAKA, S. & BENNETT, G. J. (1992). Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat. Neuroscience Letters 138, 225-228.
17. KIM, S. H. & CHUNG, J. M. (1992). An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50, 355-363.
18. KIM, K. J., YOON, Y. W. & CHUNG, J. M. (1997). Comparison of three rodent neuropathic pain models. Experimental Brain Research 113, 200-206.
19. LAIRD, J. M. A. & BENNETT, G. J. (1993). An electrophysiological study of dorsal horn neurons in the spinal cord of rats with an experimental peripheral neuropathy. Journal of Neurophysiology 69, 1-14.
20. LEE, Y.-W. & YAKSH, T. L. (1996). Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists. Journal of Pharmacology and Experimental Therapeutics 277, 1642-1648.
21. LEEM, J. W., PARK, E. S. & PAIK, K. S. (1995). Electrophysiological evidence for the antinociceptive effect of transcutaneous electrical stimulation on mechanically evoked responsiveness of dorsal horn neurons in neuropathic rats. Neuroscience Letters 192, 197-200.
22. LEKAN, H. A., CARLTON, S. M. & COGGESHALL, R. E. (1996). Sprouting of Aβ fibers into lamina II of the rat dorsal horn in peripheral neuropathy. Neuroscience Letters 208, 147-150.
23. MENDELL, L. M. (1966). Physiological properties of unmyelinated fiber projection to the spinal cord. Experimental Neurology 16, 316-332.
24. MUNGER, B. L., BENNETT, G. J. & KAJANDER, K. C. (1992). An experimental painful peripheral neuropathy due to nerve constriction. Experimental Neurology 118, 204-214.
25. NA, H. S., LEEM, J. W. & CHUNG, J. M. (1993). Abnormalities of mechanoreceptors in a rat model of neuropathic pain: possible involvement in mediating mechanical allodynia. Journal of Neurophysiology 70, 522-528.
26. PALECEK, J., DOUGHERTY, P. M., KIM, S. H., PALECKOVA, V., LEKAN, H., CHUNG, J. M., CARLTON, S. M. & WILLIS, W. D. (1992a). Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates. Journal of Neurophysiology 68, 1951-1966.
27. PALECEK, J., PALECKOVA, V., DOUGHERTY, P. M., CARLTON, S. M. & WILLIS, W. D. (1992b). Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy. Journal of Neurophysiology 67, 1562-1573.
28. PETERSEN, M., ZHANG, J., ZHANG, J. M. & LAMOTTE, R. H. (1996). Abnormal spontaneous activity and responses to norepinephrine in dissociated dorsal root ganglion cells after chronic nerve constriction. Pain 67, 391-397.
29. SELTZER, Z., DUBNER, R. & SHIR, Y. (1990). A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43, 205-218.
30. SHEEN, K. & CHUNG, J. M. (1993). Signs of neuropathic pain depend on signals from injured nerve fibres in a rat model. Brain Research 610, 62-68.
31. STUDY, R. E. & KRAL, M. G. (1996). Spontaneous action potential activity in isolated dorsal root ganglion neurons from rats with a painful neuropathy. Pain 65, 235-242.
32. TAKAISHI, K., EISELE, J. H. & CARSTENS, E. (1996). Behavioral and electrophysiological assessment of hyperalgesia and changes in dorsal horn responses following partial sciatic nerve ligation in rats. Pain 66, 297-306.
33. TAL, M. & ELIAV, E. (1996). Abnormal discharge originates at the site of nerve injury in experimental constriction neuropathy (CCI) in the rat. Pain 64, 511-518.
34. TOREBJORK, E., WAHREN, L. K., WALLIN, G., HALLIN, R. & KOLTZENBURG, M. (1995). Noradrenaline-evoked pain and neuralgia. Pain 63, 11-20.
35. WALL, P. D. & DEVOR, M. (1983). Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats. Pain 17, 321-339.
36. WEGERT, S., OSSIPOV, M. H., NICHOLS, M. L., BIAN, D., VANDERAH, T. W., MALAN, T. P. JR & PORRECA, F. (1997). Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve injured rats. Pain 71, 57-64.
37. WEIL-FUGAZZA, J., GODEFROY, F. & LE BARS, D. (1984). Increase in 5-HT synthesis in the dorsal part of the spinal cord, induced by a nociceptive stimulus: blockage by morphine. Brain Research 297, 247-264.
38. WOOLF, C. J. & DOUBELL, T. P. (1994). The pathophysiology of chronic pain - increased sensitivity to low threshold Aβ-fibre inputs. Current Opinion in Neurobiology 4, 525-534.
39. YOON, Y. W., HEUNG, S. N. & CHUNG, J. M. (1996). Contributions of injured and intact afferents to neuropathic pain in an experimental rat model. Pain 64, 27-36.
40. ZELTSER, R. & SELTZER, Z. (1994). A practical guide for the use of animal models in the study of neuropathic pain. In Touch, Temperature and Pain in Health and Disease: Mechanisms and Assessments. Progress in Pain Research and Management, vol. 3, ed. BOIVIE, J., HANSSON, P. & LINDBLOM, U., pp. 295-338. IASP Press, Seattle, USA.
41. ZIMMERMANN, M. (1983). Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110.