HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca2+ release in primary culture of striatal medium spiny neurons

European Journal of Neuroscience

Volumn 20, Issue 7, 2004, Pages 1779-1787

  Tang, Tie Shan ^a   Tu, Huiping ^a   Orban, Paul C ^b   Chan, Edmond Y W ^b   Hayden, Michael R ^b   Bezprozvanny, Ilya ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Calcium signalling; Expansion; HAP1; Huntington's disease; Knockout mouse; Polyglutamine

Indexed keywords

CALCIUM ION; GENE PRODUCT; HAP1 PROTEIN; HUNTINGTIN; INOSITOL 1,4,5 TRISPHOSPHATE; NERVE PROTEIN; UNCLASSIFIED DRUG;

ALLELISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; GENE; GENE OVEREXPRESSION; HAP1 GENE; HUNTINGTON CHOREA; KNOCKOUT MOUSE; LIPID BILAYER; MOUSE; NERVE FUNCTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; STRIATE CORTEX;

ANIMALS; CALCIUM; CELLS, CULTURED; CORPUS STRIATUM; HUNTINGTON DISEASE; INOSITOL 1,4,5-TRISPHOSPHATE; KINETICS; LIPID BILAYERS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METHOXYHYDROXYPHENYLGLYCOL; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 8144228679     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2004.03633.x     Document Type: Article

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