Aqueous extract of Iranian green tea prevents lipid peroxidation and chronic ethanol liver toxicity in rat

Journal of Pharmacology and Toxicology

Volumn 6, Issue 8, 2011, Pages 691-700

  Balouchzadeh, A ^a,b   Rahimi, H R ^a   Ebadollahi Natanzi, A R ^a,c   Minaei Zangi, B ^d   Sabzevari, O ^a,d  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c Faculty of Natural Resources   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antioxidant; Ethanol; Iranian green tea; Lipid peroxidation; Liver damage

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GREEN TEA EXTRACT; MALONALDEHYDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER CIRRHOSIS; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHRONIC TOXICITY; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; ENZYME ACTIVITY; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; SINGLE DRUG DOSE;

EID: 81155135197     PISSN: 1816496X     EISSN: 2152100X     Source Type: Journal    
DOI: 10.3923/jpt.2011.691.700     Document Type: Article

References (48)

1. Akrishnan, V.R. and V.P. Menon, 2001. Potential role of antioxidants during ethanol induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats. Cell Biol. Toxicol, 17: 11-22.
2. Ansari, J.A. and M. Jamil, 2011. Pathways of hepatic regeneration and pharmacological approaches for hepatoprotection: A brief approach. J. Pharmacol. Toxicol, 6: 24-29.
3. Arteel, G.E, 2003. Oxidants and antioxidants in alcoholic liver disease. Gastroenterology, 124: 778-790.
4. Augustyniak, A, E. Waszkiewicz and E. Skrzydlewska, 2005. Preventive action of green tea from changes in the liver antioxidant abilities of different aged rats intoxicated with ethanol. Nutrition, 21: 925-932.
5. Barclay, L.R.C, 1993. Model biomembrane: Quantitative studies of peroxidation, antioxidant action, partitioning and oxidative stress. Can. J. Chem, 71: 1-6.
6. Bradford, M.M, 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem, 72: 248-254.
7. Bruckner, J.V. and A.D. Warren, 2001. Toxic Effect of Solvents and Vapors. In: Cassaret and Doull's Toxicology: The Basic Science of Poisons, 6th Edn, Klassen, CD, (Ed.). McGrow-Hill Press, New York, pp: 893-897.
8. Chavda, R, K.R. Vadalia and R. Gokani, 2010. Hepatoprotective and antioxidant activity of root bark of Calotropis procera R. Br (Asclepediaceae). Int. J. Pharmacol, 61: 937-943.
9. Diallo, A, K. Eklu-Gadegkeku, T. Mobio, S. Moukha and A. Agbonon et al, 2009. Protective effect of Moringa oleifera Lam. and Lannea kerstingii extracts against cadmium and ethanol-induced lipid peroxidation. J. Pharmaco. Toxicol, 4: 160-166.
10. Dickinson, D.A. and H.J. Forman, 2002. Cellular glutathione and thiol metabolism. Biochem. Pharmacol, 64: 1019-1026.
11. Esterbauer, H. and K.H. Cheeseman, 1990. Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxnonenal. Methods Enzymol., 186: 407-421.
12. Feng, Q, T. Kumangai, Y. Torii, Y. Nakamura, T. Osawa and K. Uchida, 2001. Anticarcinogenic antioxidants as inhibitors against intracellular oxidative stress. Free Radic. Res., 35: 779-788.
13. Ghazi-Khansan, M., M. Karami, M. Rezayat, M. Abdollahi, B. Minaie and O. Sabzevari, 2005. The protective effects of antioxidants and propranolol on hepatotoxicity of TCDD during isolated rat liver perfusion. Int. J. Pharmacol., 1: 336-341.
14. Gheorghiu, M., C. Bara, D. Pasarica, L. Brasoveanu and C. Bleotu et al., 2004. Ethanol-induced dysfunction of hepatocytes and leukocytes in patients without liver failure. Roum. Arch. Microbiol. Immunol., 63: 5-33.
15. Graham, H.N., 1992. Green tea composition, consumption and polyphenols chemistry. Prev. Med., 21: 334-350.
16. Gujrati, V., N. Patel, V.N. Rao, K. Nandakumar, T.S. Gouda, M.D. Shalam and S.M. Shantaumar, 2007. Hep atoprotective activity of alcoholic and aqueous extract of leaves of Tylophora indica (Linn) in rats. Ind. J. Pharmacol., 37: 43-47.
17. Guo, Q.N, B.L. Zhao, M.F. Li, S.R. Shen and W.J. Xin, 1996. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biophys. Biochim. Acta-Lipid Metab., 1304: 210-222.
18. Hagen, B.F., A. Bjorneboe, GE. Bjorneboe and C.A. Drevon, 1989. Effect of chronic ethanol consumption on the content of a-tocopherol in subcellular fraction of rat liver. Alcohol Clin. Exp. Res, 13: 246-251.
19. Iyawe, H.O.T, A.O. Onigbinde and O.O. Aina, 2006. Effect of chloroquine and ascorbic acid interaction on the oxidative stress status of Plasmodium berghei infested mice. Int. J. Pharmacol, 2: 1-4.
20. Jaeschke, H, G.J. Gores, A.I. Cederbaum, J.A. Hinson, P. Dominique and J.J. Lemasters, 2002. Mechanisms of hepatotoxicity. Toxicol. Sci, 65: 166-176.
21. Jun, T, Z. Liancai and W. Bochu, 2007. Effect of ginsenosides on malondialdehyde, nitric oxide and endothelin-1 production in vascular endothelial cells suffering from lipid peroxi dationinjury. Int. J. Pharmacol, 3: 101-105.
22. Kew, M.C, 2000. Serum aminotransferase concentration as evidence of hepatocellular damage. Lancet, 355: 591-592.
23. Kirpich, LA, N.V. Solovieva, S.N. Leikhter, N.A. Shidakova and O.V. Lebedeva et al, 2008. Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: A pilot study. Alcohol, 42: 675-682.
24. Labbe, D, A. Tremblay and L. Bazient, 2006. Effect of brewing temperature and duration on green tea catechin solubilizati on: Basis for production of ECG and EGCG-enriched fraction.Sep. Purif. Technol, 49: 1-9.
25. Lieber, OS, 2000. Alcohol and the liver: Metabolism of alcohol and its role in hepatic and extrahepatic diseases. Mount. Sinai. J. Med, 67: 84-93.
26. Loguercio, C, P. Piscopo, C. Guerriero, V. De Girolamo, D. Disalvo and C. Del Vecchio Blanco, 1996. Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patient with alcoholic liver cirrhosis. Scand. J. Clin. Lab. Invest, 56: 441-447.
27. Lu, S.C, Z.Z. Huang, J.M. Yang and H. Tsukamoto, 1999. Effect of ethanol and high-fat feeding on hepatic gamma-glutamylcysteine synthetase subunit expression in the rat. Hepatology, 30: 209-214.
28. McDonough, K.H, 2003. Antioxidant nutrients and alcohol. Toxicology, 189: 89-97.
29. Meera, S, V.S.S.S. Gupta Atyam and N.S. Kumar, 2008. Immunomodulatory and antioxidant activity of a polyherbal formulation. Int. J. Pharmacol, 4: 287-291.
30. Montolin, C, S. Valles, J. Renam-piqueras and G. Guerri, 1994. Ethanol induced oxygen radical formation and lipid peroxidation in rat brain. J. Neurochem, 63: 1855-1862.
31. Natanzi, A.R.E, M.H. Ghahremam, H.R.M. Esfehani, M.B. Mmaei, H. Nazarian and O. Sabzevari, 2010. Evaluation of antihepatotoxic effect of watercress extract and its fractions in rats. Int. J. Pharmacol, 6: 896-902.
32. Niemela, O, S. Parkkila, M. Pasanen, Y. Limuro, B. Bradford and R. G. Thurman, 1998. Early alcoholic liver injury: formation of protein adducts with acetaldehyde and lipid peroxidation products and expression of CYP2E1 and CYP3A. Alcohol. Clin. Exp. Res, 22: 2118-2124.
33. Nordman, R, C. Riviere and H. Rovash, 1990. Ethanol induced lipid peroxidation and oxidative stress in extrahepatic tissues. Alcohol, 25: 231-237.
34. Odukoya, O.A, S.I. Inya-Agha and O.O. Ilori, 2007. Immune boosting herbs: Lipid peroxidation in liver homogenate as index of activity. J. Pharmacol. Toxicol, 2: 190-195.
35. Plaa, G.L. and M. Carbonneau, 2001. Detection and Evaluation of Chemically Induced Liver Injury. In: Principle and Methods of Toxicology, Hayes, A.W, (Ed.). Taylor and Francis, New York, pp: 1145-1187.
36. Polavarapu, R, D.R. Spitz, J.E. Sim, M.H. Follansbee, L.W. Oberley and A. Rahemtulla, 1998. Nanji Increased lipid peroxidatin and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats diets high in corn oil and fish oil. Hepatology, 27: 1317-1323.
37. Prasanna, G.S. and A. Purnima, 2011. Protective effect of leaf extract of Trichilia connaroides on hypercholesterolemia induced oxidative stress. Int. J. Pharmacol, 7: 106-112.
38. Radosavljevic, T, D. MLadenovic and D. Vucevic, 2009. The role of oxidative stress in alcoholic liver injury. Med. Pregl, 62: 547-553.
39. Rajagopal, S, P. Manickam, V. Periyasamy and N. Namasivayam, 2003. Activity of Cassia auriculata leaf extract in rats with alcoholic liver injury. J. Nutr. Biochem, 14: 452-458.
40. Sahm, K, C. Orhan, M. Tuzcu, S. All, N. Sahm and A. Hayirh, 2010. Epigallocatechm-3-gallate prevents lipid peroxidation and enhances antioxidant defense system via modulating hepatic nuclear transcription factors in heat-stressed quails. Poult Sci, 89: 2251-2258.
41. Sano, M, Y. Takahashi, K. Yoshino, K. Shimoi and Y. Nakamura et al, 1995. Effect of tea (Camellia sinensis L.) on lipid peroxidation in rat liver and kidney: A comparison of green and black tea feeding. Biol. Pharm. Bull, 18: 1006-1008.
42. Schisler, N.J. and S.M. Singh, 1989. Effect of ethanol in vivo on enzymes which detoxify oxygen free radicals. Free Radic. Biol. Med, 7: 117-123.
43. Shahriari, S, N. Yasa, A. Mohammadirad, R. Khorasani and M. Abdollahi, 2007. In vivo antioxidant potentials of Rosa damascene petal extract from Guilan, Iran, comparable to a-tocopherol. Int. J. Pharmacol, 3: 187-190.
44. Terao, J, M. Piskula and Q. Yao, 1994. Protective effect of epicatechin, epicatechin gallate and quercetin on lipid peroxidation in phospholipid bilayers. Arch. Biochem. Biophys, 308: 278-284.
45. Vargo, M. and L. Buris, 1990. Quantitative ultrastructural analysis of hepatoprotective effects of (+)-cyanidanol-3 on alcoholic liver damage. Exp. Mol. Pathol, 52: 249-257.
46. Wei, H, X. Zhang, J.F. Zhao, Z.Y. Wang, D. Bickers and M. Lebwohl, 1999. Scavenging of hydrogen peroxide and inhibition of ultraviolet light-induced oxidative DNA damage by aqueous extracts from green and black teas. Free. Radic. Biol. Med, 26: 1427-1435.
47. Wu, D. and A.I. Cederbaum, 2003. Alcohol, oxidative stress and free radical damage. Alcohol Res. Health, 27: 277-284.
48. Yu, B.P, 1994. Cellular defenses against damage from reactive oxygen species. Physiol. Rev, 74: 139-162.