-
1
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick, L.&P.S.Moorhead. 1961. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25: 585-621.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
2
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick, L. 1965. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37: 614-636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
3
-
-
0030038104
-
Replicative senescence: Implications for in vivo aging and tumor suppression
-
Smith, J.R. & O.M. Pereira-Smith. 1996. Replicative senescence: implications for in vivo aging and tumor suppression. Science 273: 63-67.
-
(1996)
Science
, vol.273
, pp. 63-67
-
-
Smith, J.R.1
Pereira-Smith, O.M.2
-
4
-
-
0029047362
-
A biomarker that identifies senescent humancells inculture and in aging skin in vivo
-
Dimri, G.P. et al. 1995. A biomarker that identifies senescent humancells inculture and in aging skin invivo. Proc. Natl. Acad. Sci. USA 92: 9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
-
5
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
Noda, A. et al. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211: 90-98.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
-
6
-
-
0029670840
-
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
-
Hara, E. et al. 1996. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol. 16: 859-867.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 859-867
-
-
Hara, E.1
-
7
-
-
0020610446
-
Evidence for the recessive nature of cellular immortality
-
Pereira-Smith, O.M. & J.R. Smith. 1983. Evidence for the recessive nature of cellular immortality. Science 221: 964-966.
-
(1983)
Science
, vol.221
, pp. 964-966
-
-
Pereira-Smith, O.M.1
Smith, J.R.2
-
8
-
-
0345003988
-
Assembly of BAC contig of the complementation group B cell senescence gene candidate region at 4q33-q34.1 and identification of expressed sequences
-
Bertram, M.J. et al. 1999. Assembly of BAC contig of the complementation group B cell senescence gene candidate region at 4q33-q34.1 and identification of expressed sequences. Genomics 56: 353-354.
-
(1999)
Genomics
, vol.56
, pp. 353-354
-
-
Bertram, M.J.1
-
9
-
-
0345654336
-
Identification of a gene that reverses the immortal phenotype of a subset of cells and is amember of a novel family of transcription factor-like genes
-
Bertram, M.J. et al. 1999. Identification of a gene that reverses the immortal phenotype of a subset of cells and is amember of a novel family of transcription factor-like genes. Mol. Cell. Biol. 19: 1479-1485.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1479-1485
-
-
Bertram, M.J.1
-
10
-
-
0035925659
-
Conservation of theMORF4 related gene family: Identification of a new chromodomain subfamily and novel protein motif
-
Bertram, M.J.&O.M. Pereira-Smith. 2001.Conservation of theMORF4 related gene family: identification of a new chromodomain subfamily and novel protein motif. Gene 266: 111-121.
-
(2001)
Gene
, vol.266
, pp. 111-121
-
-
Bertram, M.J.1
Pereira-Smith, O.M.2
-
11
-
-
0037184965
-
MRG15, a novel chromodomain protein, is present intwo distinctmultiprotein complexes involved in transcriptional activation
-
Pardo, P.S. et al. 2002. MRG15, a novel chromodomain protein, is present intwo distinctmultiprotein complexes involved in transcriptional activation. J. Biol. Chem. 277: 50860-50866.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50860-50866
-
-
Pardo, P.S.1
-
12
-
-
34249680106
-
The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging
-
Pena, A.N. & O.M. Pereira-Smith. 2007. The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging. Ann. N.Y. Acad. Sci. 1100: 299-305.
-
(2007)
Ann. N.Y. Acad. Sci.
, vol.1100
, pp. 299-305
-
-
Pena, A.N.1
Pereira-Smith, O.M.2
-
13
-
-
0031595103
-
Chromo-domain proteins: Linking chromatin structure to epigenetic regulation
-
Cavalli, G. & R. Paro. 1998. Chromo-domain proteins: linking chromatin structure to epigenetic regulation. Curr. Opin. Cell Biol. 10: 354-360.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 354-360
-
-
Cavalli, G.1
Paro, R.2
-
14
-
-
0033964661
-
Mammalian chromodomain proteins: Their role in genome organisation and expression
-
Jones, D.O., I.G. Cowell & P.B. Singh. 2000.Mammalian chromodomain proteins: their role in genome organisation and expression. Bioessays 22: 124-137.
-
(2000)
Bioessays
, vol.22
, pp. 124-137
-
-
Jones, D.O.1
Cowell, I.G.2
Singh, P.B.3
-
15
-
-
0029416901
-
The Polycomb and Trithorax group proteins of Drosophila: Trans-regulators of homeotic gene function
-
Kennison, J.A. 1995. The Polycomb and Trithorax group proteins ofDrosophila: trans-regulators of homeotic gene function. Annu. Rev. Genet. 29: 289-303.
-
(1995)
Annu. Rev. Genet.
, vol.29
, pp. 289-303
-
-
Kennison, J.A.1
-
16
-
-
0028802784
-
The chromo super family: New members, duplication of the chromodomain and possible role in delivering transcription regulators to chromatin
-
Koonin, E.V., S. Zhou&J.C. Lucchesi. 1995. The chromo superfamily: new members, duplication of the chromodomain and possible role in delivering transcription regulators to chromatin. Nucleic Acids Res. 23: 4229-4233.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4229-4233
-
-
Koonin, E.V.1
Zhou, S.2
Lucchesi, J.C.3
-
17
-
-
0028318372
-
Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals
-
Lorentz, A. et al. 1994. Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals. Gene 143: 139-143.
-
(1994)
Gene
, vol.143
, pp. 139-143
-
-
Lorentz, A.1
-
18
-
-
0035914347
-
MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14
-
Leung, J.K. et al. 2001. MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14. J. Biol. Chem. 276: 39171-39178.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39171-39178
-
-
Leung, J.K.1
-
19
-
-
1542782281
-
MRGX: A novel transcriptional regulator that exhibits activation or repression of B-myb promoter in a cell type dependent manner
-
Tominaga, K. et al. 2003. MRGX: a novel transcriptional regulator that exhibits activation or repression of B-myb promoter in a cell type dependent manner. J. Biol. Chem. 278: 49618-49624.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49618-49624
-
-
Tominaga, K.1
-
20
-
-
0036841723
-
Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split
-
Yochum, G.S. & D.E. Ayer. 2002. Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. Mol. Cell. Biol. 22: 7868-7876.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7868-7876
-
-
Yochum, G.S.1
Ayer, D.E.2
-
21
-
-
0242322038
-
Identification of new subunits of themultiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex
-
Cai, Y. et al. 2003. Identification of new subunits of themultiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. J. Biol. Chem. 278: 42733-42736.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 42733-42736
-
-
Cai, Y.1
-
22
-
-
1342346531
-
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans
-
Doyon, Y. et al. 2004. Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol. Cell. Biol. 24: 1884-1896.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1884-1896
-
-
Doyon, Y.1
-
23
-
-
34250782620
-
RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation
-
Hayakawa, T. et al. 2007. RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation. Genes Cells 12: 811-826.
-
(2007)
Genes Cells
, vol.12
, pp. 811-826
-
-
Hayakawa, T.1
-
24
-
-
40349092949
-
Probabilistic assembly of human protein interaction networks fromlabel-free quantitative proteomics
-
Sardiu,M.E. et al. 2008. Probabilistic assembly of human protein interaction networks fromlabel-free quantitative proteomics. Proc. Natl. Acad. Sci. USA 105: 1454-1459.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1454-1459
-
-
Sardiu, M.E.1
-
25
-
-
10844233155
-
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions
-
Kusch, T. et al. 2004. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science 306: 2084-2087.
-
(2004)
Science
, vol.306
, pp. 2084-2087
-
-
Kusch, T.1
-
26
-
-
69249088889
-
MRG15 is a novel PALB2 interacting factor involved in homologous recombination
-
Sy, S.M.-H., M.S. Y. Huen & J. Chen. 2009. MRG15 is a novel PALB2 interacting factor involved in homologous recombination. J. Biol. Chem. 284: 21127-21131.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21127-21131
-
-
Sy, S.M.-H.1
Huen, Y.M.S.2
Chen, J.3
-
27
-
-
84860105218
-
MRG15 regulates embryonic development and cell proliferation
-
Tominaga, K. et al. 2005. MRG15 regulates embryonic development and cell proliferation. Mol. Cell. Biol. 25: 2924-2937.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2924-2937
-
-
Tominaga, K.1
-
28
-
-
65849476475
-
MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells
-
Chen, M. et al. 2009. MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells. J. Neurosci. Res. 87: 1522-1531.
-
(2009)
J. Neurosci. Res.
, vol.87
, pp. 1522-1531
-
-
Chen, M.1
-
29
-
-
0029863342
-
Neurogenesis in the dentate gyrus of the adult rat: Agerelated decrease of neuronal progenitor proliferation
-
Kuhn, H.G., H. Dickinson-Anson & F.H. Gage. 1996. Neurogenesis in the dentate gyrus of the adult rat: agerelated decrease of neuronal progenitor proliferation. J. Neurosci. 16: 2027-2033.
-
(1996)
J. Neurosci.
, vol.16
, pp. 2027-2033
-
-
Kuhn, H.G.1
Dickinson-Anson, H.2
Gage, F.H.3
-
30
-
-
0032080116
-
Experience induced neurogenesis in the senescent dentate gyrus
-
Kempermann, G., H. Kuhn & F. Gage. 1998. Experience induced neurogenesis in the senescent dentate gyrus. J. Neurosci. 18: 3206-3212.
-
(1998)
J. Neurosci.
, vol.18
, pp. 3206-3212
-
-
Kempermann, G.1
Kuhn, H.2
Gage, F.3
-
31
-
-
0033306418
-
Restoring production of hippocampal neurons in old age
-
Cameron, H.A. & R.D. McKay. 1999. Restoring production of hippocampal neurons in old age. Nat. Neurosci. 2: 894-897.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 894-897
-
-
Cameron, H.A.1
McKay, R.D.2
-
32
-
-
0033609085
-
Hippocampal neurogenesis in adult OldWorld primates
-
Gould, E. et al. 1999.Hippocampal neurogenesis in adult OldWorld primates. Proc.Natl. Acad. Sci.USA 96: 5263-5267.
-
(1999)
Proc.Natl. Acad. Sci. USA
, vol.96
, pp. 5263-5267
-
-
Gould, E.1
-
33
-
-
0032909852
-
Multipotent stem/progenitor cells with similar properties arise from two neurogenic regions of adult human brain
-
Kukekov, V.G. et al. 1999. Multipotent stem/progenitor cells with similar properties arise from two neurogenic regions of adult human brain. Exp. Neurol. 156: 333-344.
-
(1999)
Exp. Neurol.
, vol.156
, pp. 333-344
-
-
Kukekov, V.G.1
-
34
-
-
0030826603
-
Transforming growth factoralpha null and senescent mice showdeceased neural progenitor cell proliferation in the forebrain subependyma
-
Tropepe, V. et al. 1997. Transforming growth factoralpha null and senescent mice showdeceased neural progenitor cell proliferation in the forebrain subependyma. J. Neurosci. 17: 7850-7859.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7850-7859
-
-
Tropepe, V.1
-
35
-
-
0037334125
-
NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus
-
Nacher, J. et al. 2003. NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus. Neurobiol. Aging 24: 273-284.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 273-284
-
-
Nacher, J.1
-
36
-
-
21344464438
-
Dynamics of neurogenesis in the dentate gyrus of adult rats
-
McDonald, H.Y. & J.M. Wojtowicz. 2005. Dynamics of neurogenesis in the dentate gyrus of adult rats. Neurosci. Lett. 385: 70-75.
-
(2005)
Neurosci. Lett.
, vol.385
, pp. 70-75
-
-
McDonald, H.Y.1
Wojtowicz, J.M.2
-
37
-
-
33344478060
-
Lifelong corticosterone level deterines age-related decline in neurogenesis and memory
-
Montaron, M.F. et al. 2005. Lifelong corticosterone level deterines age-related decline in neurogenesis and memory. Neurobiol. Aging 27: 645-654.
-
(2005)
Neurobiol. Aging
, vol.27
, pp. 645-654
-
-
Montaron, M.F.1
-
38
-
-
33749171885
-
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
-
Molofsky,A.V. et al. 2006. Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443: 448-452.
-
(2006)
Nature
, vol.443
, pp. 448-452
-
-
Molofsky, A.V.1
-
39
-
-
33751229947
-
The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus
-
Rao, M.S., B. Hattiangady & A.K. Shetty. 2006. The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus. Aging Cell 5: 545-558.
-
(2006)
Aging Cell
, vol.5
, pp. 545-558
-
-
Rao, M.S.1
Hattiangady, B.2
Shetty, A.K.3
-
40
-
-
65549125564
-
Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain
-
Ahlenius,H. et al. 2009.Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain. J. Neurosci. 29: 4408-4419.
-
(2009)
J. Neurosci.
, vol.29
, pp. 4408-4419
-
-
Ahlenius, H.1
-
41
-
-
1242341960
-
Neural stem cell detection, characerization, and age-related changes in the subventricular zone of mice
-
Maslov, A.Y. et al. 2004. Neural stem cell detection, characerization, and age-related changes in the subventricular zone of mice. J. Neurosci. 24: 1726-1733.
-
(2004)
J. Neurosci.
, vol.24
, pp. 1726-1733
-
-
Maslov, A.Y.1
-
42
-
-
0347719238
-
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
-
Shi, Y. et al. 2004. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature 427: 78-83.
-
(2004)
Nature
, vol.427
, pp. 78-83
-
-
Shi, Y.1
-
43
-
-
69249240293
-
Neural stem cells in the developing and adult brains
-
Qu,Q.&Y. Shi. 2009.Neural stem cells in the developing and adult brains. J. Cell. Physiol. 221: 5-9.
-
(2009)
J. Cell. Physiol.
, vol.221
, pp. 5-9
-
-
Qu, Q.1
Shi, Y.2
-
44
-
-
0031465159
-
Defective limbic system in mice lacking the Tailless gene
-
Monaghan, A.P. et al. 1997. Defective limbic system in mice lacking the Tailless gene. Nature 390: 515-517.
-
(1997)
Nature
, vol.390
, pp. 515-517
-
-
Monaghan, A.P.1
-
45
-
-
0042358850
-
Expression of transcription factor, Tailless, is required for formation of superficial fortical layers
-
Land, P.W. & A.P. Monaghan. 2003. Expression of transcription factor, Tailless, is required for formation of superficial fortical layers. Cereb. Cortex 13: 921-931.
-
(2003)
Cereb. Cortex
, vol.13
, pp. 921-931
-
-
Land, P.W.1
Monaghan, A.P.2
-
46
-
-
34848818037
-
Orphan nuclear receptorTLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
-
Sun, G. et al. 2007. Orphan nuclear receptorTLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proc. Natl. Acad. Sci. USA 104: 15282-15287.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 15282-15287
-
-
Sun, G.1
-
47
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Gottlicher, M. et al. 2001. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 20: 6969-6978.
-
(2001)
EMBO J.
, vol.20
, pp. 6969-6978
-
-
Gottlicher, M.1
-
48
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant,moodstabilizer, and teratogen
-
Phiel, C.J. et al. 2001.Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant,moodstabilizer, and teratogen. J. Biol. Chem. 276: 36734-36741.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
-
49
-
-
9344252804
-
Histone deacetylase inhibitionmediated neuronal differentiation of multipotent adult neural progenitor cells
-
Hsieh, J. et al. 2004. Histone deacetylase inhibitionmediated neuronal differentiation of multipotent adult neural progenitor cells. Proc. Natl. Acad. Sci. USA 101: 16659-16664.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16659-16664
-
-
Hsieh, J.1
-
50
-
-
34249779216
-
Epigenetic modulation of seizure-induced neurogenesis and cognitive decline
-
Jessberger, S. et al. 2007. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J. Neurosci. 27: 5967-5975.
-
(2007)
J. Neurosci.
, vol.27
, pp. 5967-5975
-
-
Jessberger, S.1
-
51
-
-
67650360880
-
Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons trough its epigenetic actions
-
Fukuchi, M. et al. 2009. Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons trough its epigenetic actions. Neurosci. Res. 65: 35-43.
-
(2009)
Neurosci. Res.
, vol.65
, pp. 35-43
-
-
Fukuchi, M.1
-
52
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
Cheng, H.L. et al. 2003. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Aci. USA 100: 10794-10799.
-
(2003)
Proc. Natl. Acad. Aci. USA
, vol.100
, pp. 10794-10799
-
-
Cheng, H.L.1
-
53
-
-
0037207475
-
The mammalian SIR2 protein has a role in embryogenesis and gametogenesis
-
McBurney, M.W. et al. 2003. The mammalian SIR2 protein has a role in embryogenesis and gametogenesis. Mol. Cell. Biol. 23: 38-54.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 38-54
-
-
McBurney, M.W.1
-
54
-
-
42349085704
-
Sirt 1 contributes critically to the redox-dependent fate of neural progenitors
-
Prozorovski, T. et al. 2008. Sirt 1 contributes critically to the redox-dependent fate of neural progenitors. Nat. Cell Biol. 10: 385-394.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 385-394
-
-
Prozorovski, T.1
-
55
-
-
0037123765
-
Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(sp1) bHLH repressors in segmentation and sex determination
-
Rosenberg, M.I. & S.M. Parkhurst. 2002. Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(sp1) bHLH repressors in segmentation and sex determination. Cell 109: 447-458.
-
(2002)
Cell
, vol.109
, pp. 447-458
-
-
Rosenberg, M.I.1
Parkhurst, S.M.2
-
56
-
-
0037474507
-
Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 andHEY2 and is involved in HES1- and HEY2-mediated transcriptional repression
-
Takata, T. & F. Ishikawa. 2003. Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 andHEY2 and is involved in HES1- and HEY2-mediated transcriptional repression. Biochem. Biophys. Res. Commun. 301: 250-257.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.301
, pp. 250-257
-
-
Takata, T.1
Ishikawa, F.2
-
57
-
-
0029595271
-
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects
-
Ishibashi, M. et al. 1995. Targeted disruption of mammalian Hairy and Enhancer of Split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 9: 3136-3148. (Pubitemid 26018146)
-
(1995)
Genes and Development
, vol.9
, Issue.24
, pp. 3136-3148
-
-
Ishibashi, M.1
Ang, S.-L.2
Shiota, K.3
Nakanishi, S.4
Kageyama, R.5
Guillemot, F.6
-
58
-
-
34447635892
-
Dynamic assembly of chromatin complexes during cellular senescence: Implications for the growth arrest of human melanocytic nevi
-
Bandyopadhyay, D. et al. 2007. Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging Cell 6: 577-591.
-
(2007)
Aging Cell
, vol.6
, pp. 577-591
-
-
Bandyopadhyay, D.1
-
59
-
-
0028060515
-
The retinoblastoma protein and BRG1 forma complex and cooperate to induce cell cycle arrest
-
Dunaief, J.L. et al. 1994. The retinoblastoma protein and BRG1 forma complex and cooperate to induce cell cycle arrest. Cell 79: 119-130.
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
-
60
-
-
34250007142
-
Deficiencies inDNAdamage repair limit the function of haematopoietic stem cells with age
-
Rossi,D.J. et al. 2007. Deficiencies inDNAdamage repair limit the function of haematopoietic stem cells with age. Nature 447: 725-729.
-
(2007)
Nature
, vol.447
, pp. 725-729
-
-
Rossi, D.J.1
-
62
-
-
66449086247
-
Genotoxic stress abrogates renewal ofmelanocyte stemcells by triggering their differentiation
-
Inomata, K. et al. 2009. Genotoxic stress abrogates renewal ofmelanocyte stemcells by triggering their differentiation. Cell 137: 1088-1099.
-
(2009)
Cell
, vol.137
, pp. 1088-1099
-
-
Inomata, K.1
-
63
-
-
0001183734
-
Ataxia-telangiectasia
-
Vinken, P.J., G.W. Bruyn, & H.L. Klawans, Eds.: Elsevier Science, Amsterdam
-
Sedgewick, R. & E. Boder. 1991. Ataxia-telangiectasia. In Handbook of Clinical Neurology. Vinken, P.J., G.W. Bruyn, & H.L. Klawans, Eds.: Elsevier Science, Amsterdam.
-
(1991)
Handbook of Clinical Neurology
-
-
Sedgewick, R.1
Boder, E.2
-
64
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
Barlow, C. et al. 1996. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86: 159-171.
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
-
65
-
-
0030476720
-
The product of the ATM gene is a 370-kDa nuclear phosphoprotein
-
Chen, G. & E.Y.-H. Lee. 1996. The product of the ATM gene is a 370-kDa nuclear phosphoprotein. J. Biol. Chem. 271: 33693-33697.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 33693-33697
-
-
Chen, G.1
Lee, E.Y.-H.2
-
66
-
-
0032524070
-
Requirement for Atm in ionizing radiattion-induced cell death in the developing central nervous system
-
Herzog, K.H. et al. 1998. Requirement for Atm in ionizing radiattion-induced cell death in the developing central nervous system. Science 280: 1089-1091.
-
(1998)
Science
, vol.280
, pp. 1089-1091
-
-
Herzog, K.H.1
-
67
-
-
0035281565
-
Ataxia telangiectasia mutated is essential during adult neurogenesis
-
Allen, D.M. et al. 2001. Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev. 15: 554-566.
-
(2001)
Genes Dev.
, vol.15
, pp. 554-566
-
-
Allen, D.M.1
-
68
-
-
35548941765
-
Mrg15 null and heterozygous mouse embryonic fibroblasts exhibitDNA-repair defects post exposure to gamma ionizing radiation
-
Garcia, S.N. et al. 2007. Mrg15 null and heterozygous mouse embryonic fibroblasts exhibitDNA-repair defects post exposure to gamma ionizing radiation. FEBS Lett. 581: 5275-5281.
-
(2007)
FEBS Lett.
, vol.581
, pp. 5275-5281
-
-
Garcia, S.N.1
-
69
-
-
70449704054
-
The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway
-
Tominaga, K., E. Tominaga, M.J. Ausserlechner, O.M. Pereira-Smith. 2010. The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway. Exp. Cell. Res. 316: 92-102.
-
(2010)
Exp. Cell. Res.
, vol.316
, pp. 92-102
-
-
Tominaga, K.1
Tominaga, E.2
Ausserlechner, M.J.3
Pereira-Smith, O.M.4
|