Human serotonin 5-HT2C G protein-coupled receptor homology model from the β2 adrenoceptor structure: Ligand docking and mutagenesis studies

International Journal of Quantum Chemistry

Volumn 112, Issue 1, 2012, Pages 140-149

  Córdova Sintjago, Tania ^a   Villa, Nancy ^a   Canal, Clinton ^a   Booth, Raymond ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

drug design; GPCR homology modeling; serotonin 5 HT2C receptor

Indexed keywords

DRUG DESIGN; EXPERIMENTAL STUDIES; G-PROTEIN COUPLED RECEPTORS; HOMOLOGY MODELING; HOMOLOGY MODELS; LIGAND AFFINITY; LIGAND BINDING; LIGAND DOCKING; LIGAND-RECEPTOR INTERACTIONS; LISURIDE; MODELING RESULTS; MOLECULAR DETERMINANTS; NEUROPSYCHIATRIC DISORDER; PRIMARY AMINES; SEROTONIN 5-HT2C RECEPTOR; TERTIARY AMINE; TETRAHYDRONAPHTHALENES; WILD TYPES;

CRYSTAL STRUCTURE; DRUG INTERACTIONS; LIGANDS; NAPHTHALENE; UREA;

STRUCTURAL DESIGN;

EID: 80855139563     PISSN: 00207608     EISSN: 1097461X     Source Type: Journal    
DOI: 10.1002/qua.23231     Document Type: Conference Paper

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