DKK1 antagonizes Wnt signaling without promotion of LRP6 internalization and degradation

Journal of Biological Chemistry

Volumn 283, Issue 31, 2008, Pages 21427-21432

  Semënov, Mikhail V ^a,b   Zhang, Xinjun ^a   He, Xi ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CELL CULTURE; CELL MEMBRANES; DEGRADATION; MAMMALS; SERPENTINE; SILICATE MINERALS;

CELL SURFACES; COMPLEX FORMATIONS; HIGH AFFINITIES; MAMMALIAN CELL LINES; MOLECULAR BASES; MOUSE EMBRYONIC FIBROBLASTS; POTENTIAL THERAPEUTIC TARGETS; PROTEIN LEVELS; SECRETED PROTEINS; SKELETAL DEVELOPMENTS;

SIGNAL TRANSDUCTION;

DICKKOPF 1 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PROTEIN; WNT PROTEIN; DKK1 PROTEIN, HUMAN; FRIZZLED PROTEIN; LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LRP6 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; CELL LINE; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FIBROBLAST; HALF LIFE TIME; HUMAN; HUMAN CELL; INTERNALIZATION; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; BIOTINYLATION; CELL MEMBRANE; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY;

MAMMALIA; VERTEBRATA;

ANIMALS; BIOTINYLATION; CELL LINE; CELL MEMBRANE; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LDL-RECEPTOR RELATED PROTEINS; LIGANDS; MICE; MODELS, BIOLOGICAL; RATS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 52049099892     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800014200     Document Type: Article

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