Structural and chemical basis for Glucosamine 6-phosphate binding and activation Of the glmS ribozyme

Biochemistry

Volumn 48, Issue 15, 2009, Pages 3239-3246

  Cochrane, Jesse C ^a,b,c   Lipchock, Sarah V ^a   Smith, Kathryn D ^a   Strobel, Scott A ^a  

^a YALE UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITES; ANTHRACIS; BACILLUS ANTHRACIS; BINDING MODES; CATALYTIC RNAS; COFACTOR; GLUCOSAMINE 6 PHOSPHATES; KINETIC ANALYSIS; LIGAND BINDINGS; MANNOSAMINE; PH DEPENDENCES; PHOSPHATE GROUPS; RIBOZYME; STRUCTURAL WORKS;

AMINES; BACTERIOLOGY; BINDING ENERGY; BIOCHEMISTRY; CHEMICAL ACTIVATION; GLUCOSE; LIGANDS; NUCLEIC ACIDS; RNA;

SUGAR (SUCROSE);

GLMS RIBOZYME; GLUCOSAMINE 6 PHOSPHATE; GLUCOSAMINE DERIVATIVE; MANNOSAMINE; RIBOZYME; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS ANTHRACIS; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME INACTIVATION; ENZYME MECHANISM; ENZYME STRUCTURE; GENE MUTATION; LIGAND BINDING; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN CLEAVAGE;

BACILLUS ANTHRACIS; BACTERIAL PROTEINS; BINDING, COMPETITIVE; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; GLUCOSAMINE; GLUCOSE-6-PHOSPHATE; KINETICS; LIGANDS; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; RNA, CATALYTIC; STRUCTURE-ACTIVITY RELATIONSHIP;

BACILLUS ANTHRACIS; THERMOANAEROBACTER TENGCONGENSIS;

EID: 65249184394     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802069p     Document Type: Article

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