Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

Free Radical Research

Volumn 45, Issue 11-12, 2011, Pages 1289-1306

  Ye, Xiaodong ^a,d   Fels, Diane ^b   Tovmasyan, Artak ^b   Aird, Katherine M ^b   Dedeugd, Casey ^b   Allensworth, Jennifer L ^b   Kos, Ivan ^b,c   Park, Won ^b   Spasojevic, Ivan ^b   Devi, Gayathri R ^b   Dewhirst, Mark W ^b   Leong, Kam W ^a   Batinic Haberle, Ines ^b  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Ascorbate; Cancer cells; Mn porphyrin; MnTE 2 PyP 5+; Oxidative stress; SOD mimics

Indexed keywords

ALKYLPYRIDYLPORPHYRIN; ANTINEOPLASTIC AGENT; ASCORBIC ACID; HYDROGEN; MANGANESE DERIVATIVE; PEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CATALYSIS; CELL STRAIN CACO 2; CELL STRAIN HCT116; CONTROLLED STUDY; CYTOTOXICITY; ENZYME MECHANISM; FEMALE; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; LIPOPHILICITY; MICROVASCULATURE; MOUSE; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE COUPLING; OXIDATIVE STRESS;

ANIMALS; ANTINEOPLASTIC AGENTS; ASCORBIC ACID; CACO-2 CELLS; CATALYSIS; FEMALE; HCT116 CELLS; HELA CELLS; HUMANS; ISOMERISM; METALLOPORPHYRINS; MICE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIDES; REACTIVE OXYGEN SPECIES; REDUCING AGENTS;

MUS;

EID: 80555144320     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.616199     Document Type: Article

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