-
1
-
-
80255132188
-
Steroids, sterols and the nervous system
-
W.J. Griffiths, The Royal Society of Chemistry Cambridge
-
Y. Wang, and W.J. Griffiths Steroids, sterols and the nervous system W.J. Griffiths, Metabolomics, Metabonomics and Metabolite Profiling 2008 The Royal Society of Chemistry Cambridge 71 115
-
(2008)
Metabolomics, Metabonomics and Metabolite Profiling
, pp. 71-115
-
-
Wang, Y.1
Griffiths, W.J.2
-
2
-
-
3543104951
-
Thematic review series: Brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal
-
J.M. Dietschy, and S.D. Turley Thematic review series: brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal J. Lipid Res. 45 2004 1375
-
(2004)
J. Lipid Res.
, vol.45
, pp. 1375
-
-
Dietschy, J.M.1
Turley, S.D.2
-
3
-
-
0029835410
-
Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
-
D. Lütjohann, O. Breuer, G. Ahlborg, I. Nennesmo, A. Sidén, U. Diczfalusy, and I. Björkhem Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation Proc. Natl. Acad. Sci. U. S. A. 93 1996 9799
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 9799
-
-
Lütjohann, D.1
Breuer, O.2
Ahlborg, G.3
Nennesmo, I.4
Sidén, A.5
Diczfalusy, U.6
Björkhem, I.7
-
4
-
-
0030906963
-
High levels of (24S)-24-hydroxycholesterol 3-sulfate, 24-glucuronide in the serum and urine of children with severe cholestatic liver disease
-
L.J. Meng, W.J. Griffiths, H. Nazer, Y. Yang, and J. Sjövall High levels of (24S)-24-hydroxycholesterol 3-sulfate, 24-glucuronide in the serum and urine of children with severe cholestatic liver disease J. Lipid Res. 38 1997 926
-
(1997)
J. Lipid Res.
, vol.38
, pp. 926
-
-
Meng, L.J.1
Griffiths, W.J.2
Nazer, H.3
Yang, Y.4
Sjövall, J.5
-
5
-
-
0035813114
-
From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans
-
I. Björkhem, U. Andersson, E. Ellis, G. Alvelius, L. Ellegard, U. Diczfalusy, J. Sjövall, and C. Einarsson From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans J. Biol. Chem. 276 2001 37004
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37004
-
-
Björkhem, I.1
Andersson, U.2
Ellis, E.3
Alvelius, G.4
Ellegard, L.5
Diczfalusy, U.6
Sjövall, J.7
Einarsson, C.8
-
6
-
-
37649021073
-
Oxysterols: Novel biologic roles for the 21st century
-
N.B. Javitt Oxysterols: novel biologic roles for the 21st century Steroids 73 2008 149
-
(2008)
Steroids
, vol.73
, pp. 149
-
-
Javitt, N.B.1
-
7
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
D.W. Russell The enzymes, regulation, and genetics of bile acid synthesis Annu. Rev. Biochem. 72 2003 137
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 137
-
-
Russell, D.W.1
-
8
-
-
47049112744
-
Cholesterol, reactive oxygen species, and the formation of biologically active mediators
-
R.C. Murphy, and K.M. Johnson Cholesterol, reactive oxygen species, and the formation of biologically active mediators J. Biol. Chem. 283 2008 15521
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15521
-
-
Murphy, R.C.1
Johnson, K.M.2
-
10
-
-
0342316532
-
Oxysterols: Modulators of cholesterol metabolism and other processes
-
G.J. Schroepfer Jr. Oxysterols: modulators of cholesterol metabolism and other processes Physiol. Rev. 80 2000 361
-
(2000)
Physiol. Rev.
, vol.80
, pp. 361
-
-
Schroepfer, Jr.G.J.1
-
11
-
-
77952307027
-
Analytical strategies for characterization of bile acid and oxysterol metabolomes
-
W.J. Griffiths, and J. Sjövall Analytical strategies for characterization of bile acid and oxysterol metabolomes Biochem. Biophys. Res. Commun. 396 2010 80
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 80
-
-
Griffiths, W.J.1
Sjövall, J.2
-
12
-
-
0033524420
-
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
-
B.A. Janowski, M.J. Grogan, S.A. Jones, G.B. Wisely, S.A. Kliewer, E.J. Corey, and D.J. Mangelsdorf Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta Proc. Natl. Acad. Sci. U. S. A. 96 1999 266
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 266
-
-
Janowski, B.A.1
Grogan, M.J.2
Jones, S.A.3
Wisely, G.B.4
Kliewer, S.A.5
Corey, E.J.6
Mangelsdorf, D.J.7
-
13
-
-
34249848111
-
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
-
A. Radhakrishnan, Y. Ikeda, H.J. Kwon, M.S. Brown, and J.L. Goldstein Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig Proc. Natl. Acad. Sci. U. S. A. 104 2007 6511
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 6511
-
-
Radhakrishnan, A.1
Ikeda, Y.2
Kwon, H.J.3
Brown, M.S.4
Goldstein, J.L.5
-
14
-
-
66349134748
-
Cholesterol feedback: From Schoenheimer's bottle to Scap's MELADL
-
M.S. Brown, and J.L. Goldstein Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL J. Lipid Res. 50 2009 S15 S27 Suppl.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Brown, M.S.1
Goldstein, J.L.2
-
15
-
-
77952698279
-
Bile alcohols function as the ligands of membrane-type bile acid-activated G protein-coupled receptor
-
Y. Iguchi, M. Yamaguchi, H. Sato, K. Kihira, T. Nishimaki-Mogami, and M. Une Bile alcohols function as the ligands of membrane-type bile acid-activated G protein-coupled receptor J. Lipid Res. 51 2010 1432
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1432
-
-
Iguchi, Y.1
Yamaguchi, M.2
Sato, H.3
Kihira, K.4
Nishimaki-Mogami, T.5
Une, M.6
-
16
-
-
70349730033
-
25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production
-
D.R. Bauman, A.D. Bitmansour, J.G. McDonald, B.M. Thompson, G. Liang, and D.W. Russell 25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production Proc. Natl. Acad. Sci. U. S. A. 106 2009 16764
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 16764
-
-
Bauman, D.R.1
Bitmansour, A.D.2
McDonald, J.G.3
Thompson, B.M.4
Liang, G.5
Russell, D.W.6
-
17
-
-
59449086786
-
Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions
-
S.E. Gale, E.J. Westover, N. Dudley, K. Krishnan, S. Merlin, D.E. Scherrer, X. Han, X. Zhai, H.L. Brockman, R.E. Brown, D.F. Covey, J.E. Schaffer, P. Schlesinger, and D.S. Ory Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions J. Biol. Chem. 284 2009 1755
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 1755
-
-
Gale, S.E.1
Westover, E.J.2
Dudley, N.3
Krishnan, K.4
Merlin, S.5
Scherrer, D.E.6
Han, X.7
Zhai, X.8
Brockman, H.L.9
Brown, R.E.10
Covey, D.F.11
Schaffer, J.E.12
Schlesinger, P.13
Ory, D.S.14
-
18
-
-
66349136255
-
Are side-chain oxidized oxysterols regulators also in vivo?
-
I. Björkhem Are side-chain oxidized oxysterols regulators also in vivo? J. Lipid Res. 50 2009 S213 S218 Suppl.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Björkhem, I.1
-
19
-
-
0023933622
-
Occurrence of 3 beta-hydroxy-5-cholestenoic acid, 3 beta,7 alpha-dihydroxy-5-cholestenoic acid, and 7 alpha-hydroxy-3-oxo-4-cholestenoic acid as normal constituents in human blood
-
M. Axelson, B. Mörk, and J. Sjövall Occurrence of 3 beta-hydroxy-5-cholestenoic acid, 3 beta,7 alpha-dihydroxy-5-cholestenoic acid, and 7 alpha-hydroxy-3-oxo-4-cholestenoic acid as normal constituents in human blood J. Lipid Res. 29 1988 629
-
(1988)
J. Lipid Res.
, vol.29
, pp. 629
-
-
Axelson, M.1
Mörk, B.2
Sjövall, J.3
-
20
-
-
0025045782
-
Potential bile acid precursors in plasma-possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man
-
M. Axelson, and J. Sjövall Potential bile acid precursors in plasma-possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man J. Steroid Biochem. 36 1990 631
-
(1990)
J. Steroid Biochem.
, vol.36
, pp. 631
-
-
Axelson, M.1
Sjövall, J.2
-
21
-
-
0026007201
-
Bile acid synthesis in cultured human hepatoblastoma cells
-
M. Axelson, B. Mörk, and G.T. Everson Bile acid synthesis in cultured human hepatoblastoma cells J. Biol. Chem. 266 1991 17770
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 17770
-
-
Axelson, M.1
Mörk, B.2
Everson, G.T.3
-
22
-
-
0028816863
-
Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry
-
S. Dzeletovic, O. Breuer, E. Lund, and U. Diczfalusy Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry Anal. Biochem. 225 1995 73
-
(1995)
Anal. Biochem.
, vol.225
, pp. 73
-
-
Dzeletovic, S.1
Breuer, O.2
Lund, E.3
Diczfalusy, U.4
-
23
-
-
34147141285
-
Novel route for elimination of brain oxysterols across the blood-brain barrier: Conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid
-
S. Meaney, M. Heverin, U. Panzenboeck, L. Ekström, M. Axelsson, U. Andersson, U. Diczfalusy, I. Pikuleva, J. Wahren, W. Sattler, and I. Björkhem Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid J. Lipid Res. 48 2007 944
-
(2007)
J. Lipid Res.
, vol.48
, pp. 944
-
-
Meaney, S.1
Heverin, M.2
Panzenboeck, U.3
Ekström, L.4
Axelsson, M.5
Andersson, U.6
Diczfalusy, U.7
Pikuleva, I.8
Wahren, J.9
Sattler, W.10
Björkhem, I.11
-
24
-
-
70349757041
-
Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide
-
U. Diczfalusy, K.E. Olofsson, A.M. Carlsson, M. Gong, D.T. Golenbock, O. Rooyackers, U. Flaring, and H. Bjorkbacka Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide J. Lipid Res. 50 2009 2258
-
(2009)
J. Lipid Res.
, vol.50
, pp. 2258
-
-
Diczfalusy, U.1
Olofsson, K.E.2
Carlsson, A.M.3
Gong, M.4
Golenbock, D.T.5
Rooyackers, O.6
Flaring, U.7
Bjorkbacka, H.8
-
25
-
-
79952465940
-
Cholestenoic acid is an important elimination product of cholesterol in the retina: Comparison of retinal cholesterol metabolism with that in the brain
-
N. Mast, R. Reem, I. Bederman, S. Huang, P.L. Dipatre, I. Björkhem, and I.A. Pikuleva Cholestenoic acid is an important elimination product of cholesterol in the retina: comparison of retinal cholesterol metabolism with that in the brain Invest. Ophthalmol. Vis. Sci. 52 2011 594
-
(2011)
Invest. Ophthalmol. Vis. Sci.
, vol.52
, pp. 594
-
-
Mast, N.1
Reem, R.2
Bederman, I.3
Huang, S.4
Dipatre, P.L.5
Björkhem, I.6
Pikuleva, I.A.7
-
26
-
-
0344737604
-
Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: A link between demyelination and neuronal damage
-
A. Diestel, O. Aktas, D. Hackel, I. Hake, S. Meier, C.S. Raine, R. Nitsch, F. Zipp, and O. Ullrich Activation of microglial poly(ADP-ribose)- polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage J. Exp. Med. 198 2003 1729
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1729
-
-
Diestel, A.1
Aktas, O.2
Hackel, D.3
Hake, I.4
Meier, S.5
Raine, C.S.6
Nitsch, R.7
Zipp, F.8
Ullrich, O.9
-
27
-
-
13944273308
-
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis
-
V. Leoni, D. Lütjohann, and T. Masterman Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis J. Lipid Res. 46 2005 191
-
(2005)
J. Lipid Res.
, vol.46
, pp. 191
-
-
Leoni, V.1
Lütjohann, D.2
Masterman, T.3
-
28
-
-
77951156488
-
Cerebrospinal fluid steroidomics: Are bioactive bile acids present in brain?
-
M. Ogundare, S. Theofilopoulos, A. Lockhart, L.J. Hall, E. Arenas, J. Sjövall, A.G. Brenton, Y. Wang, and W.J. Griffiths Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J. Biol. Chem. 285 2010 4666
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4666
-
-
Ogundare, M.1
Theofilopoulos, S.2
Lockhart, A.3
Hall, L.J.4
Arenas, E.5
Sjövall, J.6
Brenton, A.G.7
Wang, Y.8
Griffiths, W.J.9
-
29
-
-
69049084375
-
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
-
M.F. Farez, F.J. Quintana, R. Gandhi, G. Izquierdo, M. Lucas, and H.L. Weiner Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE Nat. Immunol. 10 2009 958
-
(2009)
Nat. Immunol.
, vol.10
, pp. 958
-
-
Farez, M.F.1
Quintana, F.J.2
Gandhi, R.3
Izquierdo, G.4
Lucas, M.5
Weiner, H.L.6
-
30
-
-
0023706095
-
5 alpha-cholest-8(14)-en-3 beta-ol-15-one, a potent regulator of cholesterol metabolism: Occurrence in rat skin
-
G.T. Emmons, P.J. St, R. Dam, M. Martin, K. Kudo, and G.J. Schroepfer Jr. 5 alpha-cholest-8(14)-en-3 beta-ol-15-one, a potent regulator of cholesterol metabolism: occurrence in rat skin J. Lipid Res. 29 1988 1039
-
(1988)
J. Lipid Res.
, vol.29
, pp. 1039
-
-
Emmons, G.T.1
St, P.J.2
Dam, R.3
Martin, M.4
Kudo, K.5
Schroepfer, Jr.G.J.6
-
31
-
-
78650905233
-
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fiction?
-
I. Björkhem, A. Lövgren-Sandblom, F. Piehl, M. Khademi, H. Pettersson, V. Leoni, T. Olsson, and U. Diczfalusy High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: fact or fiction? J. Lipid Res. 52 2011 170
-
(2011)
J. Lipid Res.
, vol.52
, pp. 170
-
-
Björkhem, I.1
Lövgren-Sandblom, A.2
Piehl, F.3
Khademi, M.4
Pettersson, H.5
Leoni, V.6
Olsson, T.7
Diczfalusy, U.8
-
33
-
-
80255132187
-
Mass spectrometry for steroid analysis
-
M. Lee, John Wiley & Sons Hoboken, NJ
-
W.J. Griffiths, M. Ogundare, A. Meljon, and Y. Wang Mass spectrometry for steroid analysis M. Lee, Applied Mass Spectroscopy Handbook 2011 John Wiley & Sons Hoboken, NJ
-
(2011)
Applied Mass Spectroscopy Handbook
-
-
Griffiths, W.J.1
Ogundare, M.2
Meljon, A.3
Wang, Y.4
-
34
-
-
0032770376
-
Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: Evidence that most of this steroid in the circulation is of pulmonary origin
-
A. Babiker, O. Andersson, D. Lindblom, L.J. van der, B. Wiklund, D. Lütjohann, U. Diczfalusy, and I. Björkhem Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin J. Lipid Res. 40 1999 1417
-
(1999)
J. Lipid Res.
, vol.40
, pp. 1417
-
-
Babiker, A.1
Andersson, O.2
Lindblom, D.3
Van Der, L.J.4
Wiklund, B.5
Lütjohann, D.6
Diczfalusy, U.7
Björkhem, I.8
-
35
-
-
0031045545
-
Metabolism of 27-, 25- and 24-hydroxycholesterol in rat glial cells and neurons
-
J. Zhang, Y. Akwa, M. el-Etr, E.E. Baulieu, and J. Sjövall Metabolism of 27-, 25- and 24-hydroxycholesterol in rat glial cells and neurons Biochem. J. 322 (Pt 1) 1997 175
-
(1997)
Biochem. J.
, vol.322
, Issue.PART 1
, pp. 175
-
-
Zhang, J.1
Akwa, Y.2
El-Etr, M.3
Baulieu, E.E.4
Sjövall, J.5
-
36
-
-
0034759769
-
Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C
-
G. Alvelius, O. Hjalmarson, W.J. Griffiths, I. Björkhem, and J. Sjövall Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C J. Lipid Res. 42 2001 1571
-
(2001)
J. Lipid Res.
, vol.42
, pp. 1571
-
-
Alvelius, G.1
Hjalmarson, O.2
Griffiths, W.J.3
Björkhem, I.4
Sjövall, J.5
-
37
-
-
0033714093
-
Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha
-
C. Song, and S. Liao Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha Endocrinology 141 2000 4180
-
(2000)
Endocrinology
, vol.141
, pp. 4180
-
-
Song, C.1
Liao, S.2
-
38
-
-
23744498856
-
Crossing the barrier: Net flux of 27-hydroxycholesterol into the human brain
-
M. Heverin, S. Meaney, D. Lütjohann, U. Diczfalusy, J. Wahren, and I. Björkhem Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain J. Lipid Res. 46 2005 1047
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1047
-
-
Heverin, M.1
Meaney, S.2
Lütjohann, D.3
Diczfalusy, U.4
Wahren, J.5
Björkhem, I.6
-
39
-
-
0842303768
-
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
-
M. Heverin, N. Bogdanovic, D. Lütjohann, T. Bayer, I. Pikuleva, L. Bretillon, U. Diczfalusy, B. Winblad, and I. Björkhem Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease J. Lipid Res. 45 2004 186
-
(2004)
J. Lipid Res.
, vol.45
, pp. 186
-
-
Heverin, M.1
Bogdanovic, N.2
Lütjohann, D.3
Bayer, T.4
Pikuleva, I.5
Bretillon, L.6
Diczfalusy, U.7
Winblad, B.8
Björkhem, I.9
-
40
-
-
0034034044
-
Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice. Assay of enzyme activities by high-resolution gas chromatography;-mass spectrometry
-
A. Honda, G. Salen, S. Shefer, Y. Matsuzaki, G. Xu, A.K. Batta, G.S. Tint, and N. Tanaka Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice. Assay of enzyme activities by high-resolution gas chromatography;-mass spectrometry J. Lipid Res. 41 2000 442
-
(2000)
J. Lipid Res.
, vol.41
, pp. 442
-
-
Honda, A.1
Salen, G.2
Shefer, S.3
Matsuzaki, Y.4
Xu, G.5
Batta, A.K.6
Tint, G.S.7
Tanaka, N.8
-
41
-
-
0041666303
-
27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: A novel metabolic pathway
-
C.A. Wassif, J. Yu, J. Cui, F.D. Porter, and N.B. Javitt 27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: a novel metabolic pathway Steroids 68 2003 497
-
(2003)
Steroids
, vol.68
, pp. 497
-
-
Wassif, C.A.1
Yu, J.2
Cui, J.3
Porter, F.D.4
Javitt, N.B.5
-
42
-
-
0025359856
-
Bile acid profiles in peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency
-
P.T. Clayton, E. Patel, A.M. Lawson, R.A. Carruthers, and J. Collins Bile acid profiles in peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency J. Clin. Invest. 85 1990 1267
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 1267
-
-
Clayton, P.T.1
Patel, E.2
Lawson, A.M.3
Carruthers, R.A.4
Collins, J.5
-
43
-
-
1642547028
-
Determination of 24S- and 27-hydroxycholesterol in plasma by high-performance liquid chromatography-mass spectrometry
-
I. Burkard, K.M. Rentsch, and E.A. von Determination of 24S- and 27-hydroxycholesterol in plasma by high-performance liquid chromatography-mass spectrometry J. Lipid Res. 45 2004 776
-
(2004)
J. Lipid Res.
, vol.45
, pp. 776
-
-
Burkard, I.1
Rentsch, K.M.2
Von, E.A.3
-
44
-
-
34548134818
-
Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism
-
A. Lövgren-Sandblom, M. Heverin, H. Larsson, E. Lundström, J. Wahren, U. Diczfalusy, and I. Björkhem Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 856 2007 15
-
(2007)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.856
, pp. 15
-
-
Lövgren-Sandblom, A.1
Heverin, M.2
Larsson, H.3
Lundström, E.4
Wahren, J.5
Diczfalusy, U.6
Björkhem, I.7
-
45
-
-
49049121010
-
Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol
-
A.E. DeBarber, D. Lütjohann, L. Merkens, and R.D. Steiner Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol Anal. Biochem. 381 2008 151
-
(2008)
Anal. Biochem.
, vol.381
, pp. 151
-
-
Debarber, A.E.1
Lütjohann, D.2
Merkens, L.3
Steiner, R.D.4
-
46
-
-
77949702635
-
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs
-
R. Solberg, D. Enot, H.P. Deigner, T. Koal, S. Scholl-Burgi, O.D. Saugstad, and M. Keller Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs PLoS. One. 5 2010 e9606
-
(2010)
PLoS. One.
, vol.5
, pp. 9606
-
-
Solberg, R.1
Enot, D.2
Deigner, H.P.3
Koal, T.4
Scholl-Burgi, S.5
Saugstad, O.D.6
Keller, M.7
-
47
-
-
78149356687
-
Lipidomics reveals a remarkable diversity of lipids in human plasma
-
O. Quehenberger, A.M. Armando, A.H. Brown, S.B. Milne, D.S. Myers, A.H. Merrill, S. Bandyopadhyay, K.N. Jones, S. Kelly, R.L. Shaner, C.M. Sullards, E. Wang, R.C. Murphy, R.M. Barkley, T.J. Leiker, C.R. Raetz, Z. Guan, G.M. Laird, D.A. Six, D.W. Russell, J.G. McDonald, S. Subramaniam, E. Fahy, and E.A. Dennis Lipidomics reveals a remarkable diversity of lipids in human plasma J. Lipid Res. 51 2010 3299
-
(2010)
J. Lipid Res.
, vol.51
, pp. 3299
-
-
Quehenberger, O.1
Armando, A.M.2
Brown, A.H.3
Milne, S.B.4
Myers, D.S.5
Merrill, A.H.6
Bandyopadhyay, S.7
Jones, K.N.8
Kelly, S.9
Shaner, R.L.10
Sullards, C.M.11
Wang, E.12
Murphy, R.C.13
Barkley, R.M.14
Leiker, T.J.15
Raetz, C.R.16
Guan, Z.17
Laird, G.M.18
Six, D.A.19
Russell, D.W.20
McDonald, J.G.21
Subramaniam, S.22
Fahy, E.23
Dennis, E.A.24
more..
-
48
-
-
41249093188
-
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
-
J.G. McDonald, B.M. Thompson, E.C. McCrum, and D.W. Russell Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry Methods Enzymol. 432 2007 145
-
(2007)
Methods Enzymol.
, vol.432
, pp. 145
-
-
McDonald, J.G.1
Thompson, B.M.2
McCrum, E.C.3
Russell, D.W.4
-
49
-
-
0030853916
-
Analysis of bile acids and bile alcohols in urine by capillary column liquid chromatography-mass spectrometry using fast atom bombardment or electrospray ionization and collision-induced dissociation
-
Y. Yang, W.J. Griffiths, H. Nazer, and J. Sjövall Analysis of bile acids and bile alcohols in urine by capillary column liquid chromatography-mass spectrometry using fast atom bombardment or electrospray ionization and collision-induced dissociation Biomed. Chromatogr. 11 1997 240
-
(1997)
Biomed. Chromatogr.
, vol.11
, pp. 240
-
-
Yang, Y.1
Griffiths, W.J.2
Nazer, H.3
Sjövall, J.4
-
50
-
-
80255137652
-
Sterol analysis in humans: The Dallas heart study. Lipid Maps Annual Meeting 2011. Lipidomics impact on systems biology
-
Jolla CA
-
D.W. Russell Sterol analysis in humans: the Dallas heart study. Lipid Maps Annual Meeting 2011. Lipidomics impact on systems biology cancer and metabolic diseases La 2011 Jolla CA
-
(2011)
Cancer and Metabolic Diseases
, vol.LA
-
-
Russell, D.W.1
-
51
-
-
33846228374
-
Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine
-
X. Jiang, D.S. Ory, and X. Han Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine Rapid Commun. Mass Spectrom. 21 2007 141
-
(2007)
Rapid Commun. Mass Spectrom.
, vol.21
, pp. 141
-
-
Jiang, X.1
Ory, D.S.2
Han, X.3
-
52
-
-
0035060286
-
Analysis of alcohols, as dimethylglycine esters, by electrospray ionization tandem mass spectrometry
-
D.W. Johnson Analysis of alcohols, as dimethylglycine esters, by electrospray ionization tandem mass spectrometry J. Mass Spectrom. 36 2001 277
-
(2001)
J. Mass Spectrom.
, vol.36
, pp. 277
-
-
Johnson, D.W.1
-
53
-
-
64749098311
-
Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS
-
A. Honda, K. Yamashita, T. Hara, T. Ikegami, T. Miyazaki, M. Shirai, G. Xu, M. Numazawa, and Y. Matsuzaki Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS J. Lipid Res. 50 2009 350
-
(2009)
J. Lipid Res.
, vol.50
, pp. 350
-
-
Honda, A.1
Yamashita, K.2
Hara, T.3
Ikegami, T.4
Miyazaki, T.5
Shirai, M.6
Xu, G.7
Numazawa, M.8
Matsuzaki, Y.9
-
54
-
-
77955426065
-
Highly sensitive and specific analysis of sterol profiles in biological samples by HPLC-ESI-MS/MS
-
A. Honda, T. Miyazaki, T. Ikegami, J. Iwamoto, K. Yamashita, M. Numazawa, and Y. Matsuzaki Highly sensitive and specific analysis of sterol profiles in biological samples by HPLC-ESI-MS/MS J. Steroid Biochem. Mol. Biol. 121 2010 556
-
(2010)
J. Steroid Biochem. Mol. Biol.
, vol.121
, pp. 556
-
-
Honda, A.1
Miyazaki, T.2
Ikegami, T.3
Iwamoto, J.4
Yamashita, K.5
Numazawa, M.6
Matsuzaki, Y.7
-
56
-
-
0030746504
-
Electrospray mass spectrometry of testosterone esters: Potential for use in doping control
-
C.H. Shackleton, H. Chuang, J. Kim, l.T.de, X, and J. Segura Electrospray mass spectrometry of testosterone esters: potential for use in doping control Steroids 62 1997 523
-
(1997)
Steroids
, vol.62
, pp. 523
-
-
Shackleton, C.H.1
Chuang, H.2
Kim, J.3
LT de, X.4
Segura, J.5
-
57
-
-
0035166103
-
Rapid monitoring assay of congenital adrenal hyperplasia with microbore high-performance liquid chromatography/electrospray ionization tandem mass spectrometry from dried blood spots
-
C.C. Lai, C.H. Tsai, F.J. Tsai, C.C. Lee, and W.D. Lin Rapid monitoring assay of congenital adrenal hyperplasia with microbore high-performance liquid chromatography/electrospray ionization tandem mass spectrometry from dried blood spots Rapid Commun. Mass Spectrom. 15 2001 2145
-
(2001)
Rapid Commun. Mass Spectrom.
, vol.15
, pp. 2145
-
-
Lai, C.C.1
Tsai, C.H.2
Tsai, F.J.3
Lee, C.C.4
Lin, W.D.5
-
58
-
-
0038035661
-
Derivatisation for the characterisation of neutral oxosteroids by electrospray and matrix-assisted laser desorption/ionisation tandem mass spectrometry: The Girard P derivative
-
W.J. Griffiths, S. Liu, G. Alvelius, and J. Sjövall Derivatisation for the characterisation of neutral oxosteroids by electrospray and matrix-assisted laser desorption/ionisation tandem mass spectrometry: the Girard P derivative Rapid Commun. Mass Spectrom. 17 2003 924
-
(2003)
Rapid Commun. Mass Spectrom.
, vol.17
, pp. 924
-
-
Griffiths, W.J.1
Liu, S.2
Alvelius, G.3
Sjövall, J.4
-
59
-
-
33645849225
-
Analysis of androgenic steroid Girard P hydrazones using multistage tandem mass spectrometry
-
J.M. Kirk, J. Tarbin, and B.J. Keely Analysis of androgenic steroid Girard P hydrazones using multistage tandem mass spectrometry Rapid Commun. Mass Spectrom. 20 2006 1247
-
(2006)
Rapid Commun. Mass Spectrom.
, vol.20
, pp. 1247
-
-
Kirk, J.M.1
Tarbin, J.2
Keely, B.J.3
-
60
-
-
34147118488
-
Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols
-
K. Karu, M. Hornshaw, G. Woffendin, K. Bodin, M. Hamberg, G. Alvelius, J. Sjövall, J. Turton, Y. Wang, and W.J. Griffiths Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols J. Lipid Res. 48 2007 976
-
(2007)
J. Lipid Res.
, vol.48
, pp. 976
-
-
Karu, K.1
Hornshaw, M.2
Woffendin, G.3
Bodin, K.4
Hamberg, M.5
Alvelius, G.6
Sjövall, J.7
Turton, J.8
Wang, Y.9
Griffiths, W.J.10
-
61
-
-
53049101328
-
Discovering oxysterols in plasma: A window on the metabolome
-
W.J. Griffiths, M. Hornshaw, G. Woffendin, S.F. Baker, A. Lockhart, S. Heidelberger, M. Gustafsson, J. Sjövall, and Y. Wang Discovering oxysterols in plasma: a window on the metabolome J. Proteome. Res. 7 2008 3602
-
(2008)
J. Proteome. Res.
, vol.7
, pp. 3602
-
-
Griffiths, W.J.1
Hornshaw, M.2
Woffendin, G.3
Baker, S.F.4
Lockhart, A.5
Heidelberger, S.6
Gustafsson, M.7
Sjövall, J.8
Wang, Y.9
-
62
-
-
0020794824
-
Selective reactions in the analytical characterisation of steroids by gas chromatography-mass spectrometry
-
C.J. Brooks, W.J. Cole, T.D. Lawrie, J. MacLachlan, J.H. Borthwick, and G.M. Barrett Selective reactions in the analytical characterisation of steroids by gas chromatography-mass spectrometry J. Steroid Biochem. 19 1983 189
-
(1983)
J. Steroid Biochem.
, vol.19
, pp. 189
-
-
Brooks, C.J.1
Cole, W.J.2
Lawrie, T.D.3
MacLachlan, J.4
Borthwick, J.H.5
Barrett, G.M.6
-
63
-
-
0034175781
-
Cholesterol oxidase: Sources, physical properties and analytical applications
-
J. MacLachlan, A.T. Wotherspoon, R.O. Ansell, and C.J. Brooks Cholesterol oxidase: sources, physical properties and analytical applications J. Steroid Biochem. Mol. Biol. 72 2000 169
-
(2000)
J. Steroid Biochem. Mol. Biol.
, vol.72
, pp. 169
-
-
MacLachlan, J.1
Wotherspoon, A.T.2
Ansell, R.O.3
Brooks, C.J.4
-
64
-
-
33344455802
-
Analysis of oxysterols by electrospray tandem mass spectrometry
-
W.J. Griffiths, Y. Wang, G. Alvelius, S. Liu, K. Bodin, and J. Sjövall Analysis of oxysterols by electrospray tandem mass spectrometry J. Am. Soc. Mass Spectrom. 17 2006 341
-
(2006)
J. Am. Soc. Mass Spectrom.
, vol.17
, pp. 341
-
-
Griffiths, W.J.1
Wang, Y.2
Alvelius, G.3
Liu, S.4
Bodin, K.5
Sjövall, J.6
-
65
-
-
30044432560
-
Matrix-assisted laser desorption/ionization high-energy collision-induced dissociation of steroids: Analysis of oxysterols in rat brain
-
Y. Wang, M. Hornshaw, G. Alvelius, K. Bodin, S. Liu, J. Sjövall, and W.J. Griffiths Matrix-assisted laser desorption/ionization high-energy collision-induced dissociation of steroids: analysis of oxysterols in rat brain Anal. Chem. 78 2006 164
-
(2006)
Anal. Chem.
, vol.78
, pp. 164
-
-
Wang, Y.1
Hornshaw, M.2
Alvelius, G.3
Bodin, K.4
Liu, S.5
Sjövall, J.6
Griffiths, W.J.7
-
66
-
-
65349142492
-
Targeted lipidomic analysis of oxysterols in the embryonic central nervous system
-
Y. Wang, K.M. Sousa, K. Bodin, S. Theofilopoulos, P. Sacchetti, M. Hornshaw, G. Woffendin, K. Karu, J. Sjövall, E. Arenas, and W.J. Griffiths Targeted lipidomic analysis of oxysterols in the embryonic central nervous system Mol. Biosyst. 5 2009 529
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 529
-
-
Wang, Y.1
Sousa, K.M.2
Bodin, K.3
Theofilopoulos, S.4
Sacchetti, P.5
Hornshaw, M.6
Woffendin, G.7
Karu, K.8
Sjövall, J.9
Arenas, E.10
Griffiths, W.J.11
-
67
-
-
48949097892
-
Potential of sterol analysis by liquid chromatography-tandem mass spectrometry for the prenatal diagnosis of Smith-Lemli-Opitz syndrome
-
W.J. Griffiths, Y. Wang, K. Karu, E. Samuel, S. McDonnell, M. Hornshaw, and C. Shackleton Potential of sterol analysis by liquid chromatography-tandem mass spectrometry for the prenatal diagnosis of Smith-Lemli-Opitz syndrome Clin. Chem. 54 2008 1317
-
(2008)
Clin. Chem.
, vol.54
, pp. 1317
-
-
Griffiths, W.J.1
Wang, Y.2
Karu, K.3
Samuel, E.4
McDonnell, S.5
Hornshaw, M.6
Shackleton, C.7
-
69
-
-
67650523965
-
Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow
-
F. Ali, M. Zakkar, K. Karu, E.A. Lidington, S.S. Hamdulay, J.J. Boyle, M. Zloh, A. Bauer, D.O. Haskard, P.C. Evans, and J.C. Mason Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow J. Biol. Chem. 284 2009 18882
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 18882
-
-
Ali, F.1
Zakkar, M.2
Karu, K.3
Lidington, E.A.4
Hamdulay, S.S.5
Boyle, J.J.6
Zloh, M.7
Bauer, A.8
Haskard, D.O.9
Evans, P.C.10
Mason, J.C.11
-
70
-
-
79955617129
-
Profiling sterols in cerebrotendinous xanthomatosis: Utility of Girard derivatization and high resolution exact mass LC-ESI-MS(n) analysis
-
A.E. DeBarber, Y. Sandlers, A.S. Pappu, L.S. Merkens, P.B. Duell, S.R. Lear, S.K. Erickson, and R.D. Steiner Profiling sterols in cerebrotendinous xanthomatosis: utility of Girard derivatization and high resolution exact mass LC-ESI-MS(n) analysis J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879 2011 1384
-
(2011)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.879
, pp. 1384
-
-
Debarber, A.E.1
Sandlers, Y.2
Pappu, A.S.3
Merkens, L.S.4
Duell, P.B.5
Lear, S.R.6
Erickson, S.K.7
Steiner, R.D.8
-
71
-
-
84856520590
-
Development and application of novel analytical methods in lipidomics
-
F. Darvas, A. Guttman, G. Dormán, Taylor & Francis Group Boca Raton, Florida
-
Y. Wang, A. Meljon, M. Ogundare, and W.J. Griffiths Development and application of novel analytical methods in lipidomics F. Darvas, A. Guttman, G. Dormán, Chemical Genomics and Proteomics 2011 Taylor & Francis Group Boca Raton, Florida
-
(2011)
Chemical Genomics and Proteomics
-
-
Wang, Y.1
Meljon, A.2
Ogundare, M.3
Griffiths, W.J.4
-
72
-
-
80255123940
-
-
A. Meljon, Y. Wang, and W.J. Griffiths Oxysterols in Newborn Mouse, Brain. Lipid Maps Annual Meeting 2011. Lipidomics impact on system Biology, cancer and metabolic diseases, La Jolla, CA 2011
-
(2011)
Oxysterols in Newborn Mouse, Brain. Lipid Maps Annual Meeting 2011. Lipidomics Impact on System Biology, Cancer and Metabolic Diseases, la Jolla, CA
-
-
Meljon, A.1
Wang, Y.2
Griffiths, W.J.3
-
73
-
-
33746095457
-
The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols
-
G.S. Tint, H. Yu, Q. Shang, G. Xu, and S.B. Patel The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols J. Lipid Res. 47 2006 1535
-
(2006)
J. Lipid Res.
, vol.47
, pp. 1535
-
-
Tint, G.S.1
Yu, H.2
Shang, Q.3
Xu, G.4
Patel, S.B.5
-
74
-
-
0034955877
-
Cholesterol dynamics in the foetal and neonatal brain as reflected by circulatory levels of 24S-hydroxycholesterol
-
D. Lütjohann, I. Björkhem, S. Locatelli, C. Dame, J. Schmolling, B.K. von, and H. Fahnenstich Cholesterol dynamics in the foetal and neonatal brain as reflected by circulatory levels of 24S-hydroxycholesterol Acta Paediatr. 90 2001 652
-
(2001)
Acta Paediatr.
, vol.90
, pp. 652
-
-
Lütjohann, D.1
Björkhem, I.2
Locatelli, S.3
Dame, C.4
Schmolling, J.5
Von, B.K.6
Fahnenstich, H.7
-
75
-
-
70349309626
-
Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells
-
P. Sacchetti, K.M. Sousa, A.C. Hall, I. Liste, K.R. Steffensen, S. Theofilopoulos, C.L. Parish, C. Hazenberg, L.A. Richter, O. Hovatta, J.A. Gustafsson, and E. Arenas Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells Cell Stem Cell 5 2009 409
-
(2009)
Cell Stem Cell
, vol.5
, pp. 409
-
-
Sacchetti, P.1
Sousa, K.M.2
Hall, A.C.3
Liste, I.4
Steffensen, K.R.5
Theofilopoulos, S.6
Parish, C.L.7
Hazenberg, C.8
Richter, L.A.9
Hovatta, O.10
Gustafsson, J.A.11
Arenas, E.12
-
76
-
-
1242297067
-
Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain
-
N. Mano, T. Goto, M. Uchida, K. Nishimura, M. Ando, N. Kobayashi, and J. Goto Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain J. Lipid Res. 45 2004 295
-
(2004)
J. Lipid Res.
, vol.45
, pp. 295
-
-
Mano, N.1
Goto, T.2
Uchida, M.3
Nishimura, K.4
Ando, M.5
Kobayashi, N.6
Goto, J.7
-
77
-
-
33846483721
-
Analysis of neurosterols and neurosteroids by mass spectrometry
-
Y. Wang, K. Karu, and W.J. Griffiths Analysis of neurosterols and neurosteroids by mass spectrometry Biochimie 89 2007 182
-
(2007)
Biochimie
, vol.89
, pp. 182
-
-
Wang, Y.1
Karu, K.2
Griffiths, W.J.3
-
78
-
-
0018178473
-
Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile
-
S.D. Turley, and J.M. Dietschy Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile J. Lipid Res. 19 1978 924
-
(1978)
J. Lipid Res.
, vol.19
, pp. 924
-
-
Turley, S.D.1
Dietschy, J.M.2
|