-
1
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 2007 117 : 514 521.
-
(2007)
J Clin Invest
, vol.117
, pp. 514-521
-
-
Strober, W.1
Fuss, I.2
Mannon, P.3
-
2
-
-
33745775434
-
Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis
-
Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol 2006 3 : 390 407.
-
(2006)
Nat Clin Pract Gastroenterol Hepatol
, vol.3
, pp. 390-407
-
-
Sartor, R.B.1
-
3
-
-
0031057872
-
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
-
Parronchi P, Romagnani P, Annunziato F, et al. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol 1997 150 : 823 832.
-
(1997)
Am J Pathol
, vol.150
, pp. 823-832
-
-
Parronchi, P.1
Romagnani, P.2
Annunziato, F.3
-
4
-
-
0030995575
-
Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
-
Monteleone G, Biancone L, Marasco R, et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997 112 : 1169 1178.
-
(1997)
Gastroenterology
, vol.112
, pp. 1169-1178
-
-
Monteleone, G.1
Biancone, L.2
Marasco, R.3
-
5
-
-
0030209985
-
Disparate CD4 + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
Fuss IJ, Neurath M, Boirivant M, et al. Disparate CD4 + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996 157 : 1261 1270.
-
(1996)
J Immunol
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
-
6
-
-
0031573593
-
A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease
-
Plevy SE, Landers CJ, Prehn J, et al. A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease. J Immunol 1997 159 : 6276 6282.
-
(1997)
J Immunol
, vol.159
, pp. 6276-6282
-
-
Plevy, S.E.1
Landers, C.J.2
Prehn, J.3
-
7
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
Mannon PJ, Fuss IJ, Mayer L, et al. Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med 2004 351 : 2069 2079.
-
(2004)
N Engl J Med
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
-
8
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000 13 : 715 725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
-
9
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005 201 : 233 240.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
-
10
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003 278 : 1910 1914.
-
(2003)
J Biol Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
11
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006 116 : 1310 1316.
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
-
12
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
Hue S, Ahern P, Buonocore S, et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med 2006 203 : 2473 2483.
-
(2006)
J Exp Med
, vol.203
, pp. 2473-2483
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
-
13
-
-
33750530394
-
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
-
Kullberg MC, Jankovic D, Feng CG, et al. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J Exp Med 2006 203 : 2485 2494.
-
(2006)
J Exp Med
, vol.203
, pp. 2485-2494
-
-
Kullberg, M.C.1
Jankovic, D.2
Feng, C.G.3
-
14
-
-
33747089041
-
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
-
Uhlig HH, McKenzie BS, Hue S, et al. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 2006 25 : 309 318.
-
(2006)
Immunity
, vol.25
, pp. 309-318
-
-
Uhlig, H.H.1
McKenzie, B.S.2
Hue, S.3
-
15
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
DOI 10.1136/gut.52.1.65
-
Fujino S, Andoh A, Bamba S, et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 2003 52 : 65 70. (Pubitemid 36020767)
-
(2003)
Gut
, vol.52
, Issue.1
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
Ogawa, A.4
Hata, K.5
Araki, Y.6
Bamba, T.7
Fujiyama, Y.8
-
16
-
-
13944281011
-
Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
-
Schmidt C, Giese T, Ludwig B, et al. Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm Bowel Dis 2005 11 : 16 23.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 16-23
-
-
Schmidt, C.1
Giese, T.2
Ludwig, B.3
-
17
-
-
56549104968
-
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
-
Kobayashi T, Okamoto S, Hisamatsu T, et al. IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease. Gut 2008 57 : 1682 1689.
-
(2008)
Gut
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
Okamoto, S.2
Hisamatsu, T.3
-
18
-
-
72549107316
-
Differential regulation of interleukin-17 and interferon-[gamma] production in inflammatory bowel disease
-
Rovedatti L, Kudo T, Biancheri P, et al. Differential regulation of interleukin-17 and interferon-[gamma] production in inflammatory bowel disease. Gut 2009 58 : 1629 1636.
-
(2009)
Gut
, vol.58
, pp. 1629-1636
-
-
Rovedatti, L.1
Kudo, T.2
Biancheri, P.3
-
19
-
-
36749038197
-
Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease
-
Kugathasan S, Saubermann LJ, Smith L, et al. Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease. Gut 2007 56 : 1696 1705.
-
(2007)
Gut
, vol.56
, pp. 1696-1705
-
-
Kugathasan, S.1
Saubermann, L.J.2
Smith, L.3
-
20
-
-
33144459948
-
European evidence based consensus on the diagnosis and management of Crohn's disease: Current management
-
Travis SP, Stange EF, Lemann M, et al. European evidence based consensus on the diagnosis and management of Crohn's disease: current management. Gut 2006 55 (Suppl 1 i16 35.
-
(2006)
Gut
, vol.55
, Issue.SUPPL. 1
, pp. 16-35
-
-
Travis, S.P.1
Stange, E.F.2
Lemann, M.3
-
21
-
-
0030872223
-
Migration of human intestinal lamina propria lymphocytes, macrophages and eosinophils following the loss of surface epithelial cells
-
Mahida YR, Galvin AM, Gray T, et al. Migration of human intestinal lamina propria lymphocytes, macrophages and eosinophils following the loss of surface epithelial cells. Clin Exp Immunol 1997 109 : 377 386.
-
(1997)
Clin Exp Immunol
, vol.109
, pp. 377-386
-
-
Mahida, Y.R.1
Galvin, A.M.2
Gray, T.3
-
22
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato F, Cosmi L, Santarlasci V, et al. Phenotypic and functional features of human Th17 cells. J Exp Med 2007 204 : 1849 1861.
-
(2007)
J Exp Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
-
23
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
Liang SC, Tan XY, Luxenberg DP, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006 203 : 2271 2279.
-
(2006)
J Exp Med
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
Tan, X.Y.2
Luxenberg, D.P.3
-
24
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T, Bettelli E, Gao W, et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007 448 : 484 487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
-
25
-
-
15744390341
-
Interleukin-21 enhances T-helper cell type i signaling and interferon-gamma production in Crohn's disease
-
Monteleone G, Monteleone I, Fina D, et al. Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease. Gastroenterology 2005 128 : 687 694.
-
(2005)
Gastroenterology
, vol.128
, pp. 687-694
-
-
Monteleone, G.1
Monteleone, I.2
Fina, D.3
-
26
-
-
44049102724
-
A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses
-
Volpe E, Servant N, Zollinger R, et al. A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat Immunol 2008 9 : 650 657.
-
(2008)
Nat Immunol
, vol.9
, pp. 650-657
-
-
Volpe, E.1
Servant, N.2
Zollinger, R.3
-
27
-
-
33644964894
-
Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells
-
Hoeve MA, Savage ND, de Boer T, et al. Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells. Eur J Immunol 2006 36 : 661 670.
-
(2006)
Eur J Immunol
, vol.36
, pp. 661-670
-
-
Hoeve, M.A.1
Savage, N.D.2
De Boer, T.3
-
28
-
-
67650215944
-
Persistent retention of colitogenic CD4(+) memory T cells causes inflammatory bowel diseases to become intractable
-
Kanai T, Nemoto Y, Tomita T, Totsuka T, Watanabe M, Hibi T. Persistent retention of colitogenic CD4(+) memory T cells causes inflammatory bowel diseases to become intractable. Inflamm Bowel Dis 2008 15 : 926 934.
-
(2008)
Inflamm Bowel Dis
, vol.15
, pp. 926-934
-
-
Kanai, T.1
Nemoto, Y.2
Tomita, T.3
Totsuka, T.4
Watanabe, M.5
Hibi, T.6
-
29
-
-
47049123789
-
Continuous generation of colitogenic CD4(+) T cells in persistent colitis
-
Tomita T, Kanai T, Fujii T, et al. Continuous generation of colitogenic CD4(+) T cells in persistent colitis. Eur J Immunol 2008 38 : 1264 1274.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1264-1274
-
-
Tomita, T.1
Kanai, T.2
Fujii, T.3
-
30
-
-
0038783387
-
Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: Control by CD4 + regulatory T cells and IL-10
-
Asseman C, Read S, Powrie F. Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4 + regulatory T cells and IL-10. J Immunol 2003 171 : 971 978.
-
(2003)
J Immunol
, vol.171
, pp. 971-978
-
-
Asseman, C.1
Read, S.2
Powrie, F.3
|