Activation of Syk protein tyrosine kinase through interaction with integrin β cytoplasmic domains

Current Biology

Volumn 11, Issue 22, 2001, Pages 1799-1804

  Woodside, Darren G ^a   Obergfell, Achim ^a   Leng, Lijun ^a   Wilsbacher, Julie L ^b   Miranti, Cindy K ^a   Brugge, Joan S ^b   Shattil, Sanford J ^a   Ginsberg, Mark H ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CRICETINAE;

EID: 0035856483     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00565-6     Document Type: Article

References (21)

1. The Syk family of protein tyrosine kinases in T-cell activation and development
2. Syk tyrosine kinase required for mouse viability and B-cell development
3. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
4. Regulation of the protein tyrosine kinase pp72SYK by platelet agonists and the integrin αIIbβ3
5. Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3
6. Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1
7. Activation of integrin-beta3-associated syk in platelets
8. Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk
9. Integrin β cytoplasmic domains differentially bind to cytoskeletal proteins
10. NMR analysis of structure and dynamics of the cytosolic tails of integrin alphaIIbbeta3 in aqueous solution
11. 3 subunit
12. 3 (GPIIb-IIIa) to talin
13. Tandem SH2 domains confer high specificity in tyrosine kinase signaling
14. Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE
15. Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity
16. Syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction
17. Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase
18. Signaling by adhesion in human neutrophils: Activation of the p72syk tyrosine kinase and formation of protein complexes containing p72syk and Src family kinases in neutrophiis spreading over fibrinogen
19. ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration
20. Structure and function of syk protein-tyrosine kinase
21. Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI