Synthesis and antitumor activity of β-carboline 3-(substituted- carbohydrazide) derivatives

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 21, 2011, Pages 6400-6408

  Barbosa, Valéria Aquilino ^a   Formagio, Anelise S Nazari ^a   Savariz, Franciele Cristina ^a   Foglio, Mary Ann ^b   Spindola, Humberto Moreira ^b   De Carvalho, João Ernesto ^b   Meyer, Emerson ^a   Sarragiotto, Maria Helena ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Antitumor activity; Carbohydrazides; Ehrlich tumor; Carboline derivatives

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CARBOLINE 3 N BENZYLIDENE CARBOHYDRAZIDE DERIVATIVE; BETA CARBOLINE DERIVATIVE; FLUOROURACIL; N' (4 DIMETHYLAMINOBENZYLIDENE) 9 METHYL 1 (3 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 (2 CHLOROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 (3 HYDROXY 4 METHOXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 (3 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 (4 HYDROXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 (4 METHOXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 (4 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 PHENYL BETA CARBOLINE 3 CARBOHYDRAZIDE; N' 2 PROPYLIDENE 1 [4 (DIMETHYLAMINO)PHENYL] BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 (2 CHLOROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 (3 HYDROXY 4 METHOXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 (3 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 (4 HYDROXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 (4 METHOXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 (4 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 PHENYL BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOHEXYLIDENE 1 [4 (DIMETHYLAMINO)PHENYL] BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 (2 CHLOROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 (3 HYDROXY 4 METHOXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 (3 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 (4 HYDROXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 (4 METHOXYPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 (4 NITROPHENYL) BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 PHENYL BETA CARBOLINE 3 CARBOHYDRAZIDE; N' CYCLOPENTYLIDENE 1 [4 (DIMETHYLAMINO)PHENYL] BETA CARBOLINE 3 CARBOHYDRAZIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CANCER; LEUKEMIA; LUNG CANCER; MELANOMA; MOUSE; NONHUMAN; OVARY CANCER; PROSTATE CANCER; TREATMENT RESPONSE; TUMOR GROWTH;

EID: 80054953952     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.08.059     Document Type: Article

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