Synthesis and antiviral activity of β-carboline derivatives bearing a substituted carbohydrazide at C-3 against poliovirus and herpes simplex virus (HSV-1)

European Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2009, Pages 4695-4701

  Nazari Formagio, Anelise S ^a   Santos, Patricia R ^a   Zanoli, Karine ^a   Ueda Nakamura, Tania ^a   Düsman Tonin, Lilian T ^a   Nakamura, Celso V ^a   Sarragiotto, Maria Helena ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

1,3 Disubstituted carboline derivatives; Antiviral activity; Carbohydrazide derivatives

Indexed keywords

1 (3 NITROPHENYL) N' (4 METHOXYBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (3 NITROPHENYL) N' (4 N,N DIMETHYLAMINOBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 HYDROXYPHENYL) N' (2 CHLOROBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 HYDROXYPHENYL) N' (4 METHOXYBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 HYDROXYPHENYL) N' (4 N,N DIMETHYLAMINOBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 HYDROXYPHENYL) N' (4 NITROBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 HYDROXYPHENYL) N' (BENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 METHOXYPHENYL) N' (4 METHOXYBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 METHOXYPHENYL) N' (4 N,N DIMETHYLAMINOBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 METHOXYPHENYL) N' (4 NITROBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 METHOXYPHENYL) N' (BENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 NITROPHENYL) N' (4 METHOXYBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 NITROPHENYL) N' (4 N,N DIMETHYLAMINOBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (4 NITROPHENYL) N' (BENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (PHENYL) N' (2 CHLOROBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (PHENYL) N' (4 METHOXYBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (PHENYL) N' (4 N,N DIMETHYLAMINOBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (PHENYL) N' (BENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; 1 (PHENYL) N' [1 (4 NITROBENZYLIDENE) 9H PYRIDO[3,4 B]INDOLE 3 CARBOHYDRAZIDE; BETA CARBOLINE DERIVATIVE; CARBOHYDRAZIDE DERIVATIVE; HYDRAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CYTOTOXICITY; DRUG ABSORPTION; DRUG STRUCTURE; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; LIPOPHILICITY; POLIOMYELITIS VIRUS; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CARBOLINES; CERCOPITHECUS AETHIOPS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; MICROBIAL SENSITIVITY TESTS; POLIOMYELITIS; POLIOVIRUS; VERO CELLS;

EID: 70349774236     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.07.005     Document Type: Article

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