An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its β-carboline alkaloids

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue 1, 2002, Pages 19-23

  Sobhani, Armin Madadkar ^a   Ebrahimi, Sultan Ahmad ^a   Mahmoudian, Massoud ^a  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; BETA CARBOLINE DERIVATIVE; DNA TOPOISOMERASE; HARMALINE; HARMAN; HARMINE; PEGANUM HARMALA EXTRACT; PLASMID DNA; TENIPOSIDE;

AGAR GEL ELECTROPHORESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA PURIFICATION; DNA SUPERCOILING; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; ENZYME DEGRADATION; ENZYME INHIBITION; ETHNOPHARMACOLOGY; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IC 50; IN VITRO STUDY; PLACENTA; PLANT SEED;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DNA TOPOISOMERASES, TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HUMANS; PLACENTA; PLANT EXTRACTS; SEEDS; ZYGOPHYLLACEAE;

EID: 0036234519     PISSN: 14821826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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