Synthesis and cytotoxic evaluation of 1-carboxamide and 1-amino side chain substituted β-carbolines

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 5513-5519

  Ma, Chunming ^a   Cao, Rihui ^a   Shi, Buxi ^a   Zhou, Xiantai ^a   Ma, Qin ^b   Sun, Jie ^b   Guo, Liang ^b   Yi, Wei ^a   Chen, Zhiyong ^a   Song, Huacan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Xinjiang Huashidan Pharmaceutical Co Ltd   (China)

Author keywords

Carboline; Cytotoxic; SARs; Synthesis

Indexed keywords

1 (2 AMINOETHYLAMINO) 9 (3 PHENYLPROPYL) B CARBOLINE HYDROCHLORIDE SALT; 1 (2 AMINOETHYLAMINO) 9 (4 FLUOROBENZYL) BETA CARBOLINE; 1 (2 AMINOETHYLAMINO) 9 BUTYL BETA CARBOLINE HYDROCHLORIDE SALT; 1 (2 AMINOETHYLAMINO) 9 PERFLUOROBENZYL BETA CARBOLINE; 1 (2 AMINOETHYLAMINO) BETA CARBOLINE; 1 (2 HYDROXYLETHYLAMINO) BETA CARBOLINE; 1 (4 AMINOBUTYLAMINO) 9 (3 PHENYLPROPYL) BETA CARBOLINE; 1 (6 AMINOHEXYLAMINO) 9 (3 PHENYLPROPYL) BETA CARBOLINE HYDROCHLORIDE SALT; 1 BROMO 9 (3 PHENYLPROPYL) B CARBOLINE; 1 BROMO 9 (4 FLUOROBENZYL) BETA CARBOLINE; 1 BROMO 9 BUTYL BETA CARBOLINE; 1 BROMO 9 PERFLUOROBENZYL BETA CARBOLINE; 3 (BETA CARBOLINE 1 CARBONYL)AMINOPROPYL DIETHYL BENZYL AMMONIUM BROMIDE; 3 (BETA CARBOLINE 1 CARBONYL)AMINOPROPYL DIETHYL METHYL AMMONIUM IODIDE; BETA CARBOLINE DERIVATIVE; N (2 AMINOETHYL) 9 (3 PHENYLPROPYL) BETA CARBOLINE 1 CARBOXAMIDE HYDROCHLORIDE SALT; N (2 AMINOETHYL) BETA CARBOLINE 1 CARBOXAMIDE; N (6 AMINOHEXYL) BETA CARBOLINE 1 CARBOXAMIDE HYDROCHLORIDE SALT; N [(3 DIETHYLAMINO)PROPYL] 9 (3 PHENYLPROPYL) B CARBOLINE 1 CARBOXAMIDE HYDROCHLORIDE SALT; N [(3 DIETHYLAMINO)PROPYL] BETA CARBOLINE 1 CARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HEPG2; CELL STRAIN HT29; CELL STRAIN MCF 7; CLINICAL EVALUATION; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HETERONUCLEAR NUCLEAR MAGNETIC RESONANCE; HUMAN; IC 50; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

AMIDES; CARBOLINES; DRUG SCREENING ASSAYS, ANTITUMOR; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77957835162     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.08.065     Document Type: Article

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