-
1
-
-
23844445847
-
17beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade
-
Borrás C., Gambini J., Gómez-Cabrera M.C., Sastre J., Pallardó F.V., Mann G.E., Viña J. 17beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade. Aging Cell 2005, 4:113-118.
-
(2005)
Aging Cell
, vol.4
, pp. 113-118
-
-
Borrás, C.1
Gambini, J.2
Gómez-Cabrera, M.C.3
Sastre, J.4
Pallardó, F.V.5
Mann, G.E.6
Viña, J.7
-
2
-
-
0029417023
-
Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
-
Busciglio J., Yankner B.A. Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 1995, 378:776-779.
-
(1995)
Nature
, vol.378
, pp. 776-779
-
-
Busciglio, J.1
Yankner, B.A.2
-
3
-
-
0034762806
-
Down syndrome: advances in molecular biology and the neurosciences
-
Capone G.T. Down syndrome: advances in molecular biology and the neurosciences. J. Dev. Behav. Pediatr 2001, 22:40-59.
-
(2001)
J. Dev. Behav. Pediatr
, vol.22
, pp. 40-59
-
-
Capone, G.T.1
-
4
-
-
77952955690
-
Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome
-
Contestabile A., Benfenati F., Gasparini L. Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome. Prog. Neurobiol 2010, 91:1-22.
-
(2010)
Prog. Neurobiol
, vol.91
, pp. 1-22
-
-
Contestabile, A.1
Benfenati, F.2
Gasparini, L.3
-
5
-
-
34548496286
-
Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy
-
Conti A., Fabbrini F., D'Agostino P., Negri R., Greco D., Genesio R., D'Armiento M., Olla C., Paladini D., Zannini M., Nitsch L. Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy. BMC Genomics 2007, 8:268.
-
(2007)
BMC Genomics
, vol.8
, pp. 268
-
-
Conti, A.1
Fabbrini, F.2
D'Agostino, P.3
Negri, R.4
Greco, D.5
Genesio, R.6
D'Armiento, M.7
Olla, C.8
Paladini, D.9
Zannini, M.10
Nitsch, L.11
-
6
-
-
0026778904
-
Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria
-
Estornell E., Fato R., Castelluccio C., Cavazzoni M., Parenti Castelli G., Lenaz G. Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria. FEBS Lett 1992, 311:107-109.
-
(1992)
FEBS Lett
, vol.311
, pp. 107-109
-
-
Estornell, E.1
Fato, R.2
Castelluccio, C.3
Cavazzoni, M.4
Parenti Castelli, G.5
Lenaz, G.6
-
7
-
-
34248592696
-
Rapid measurement of total antioxidant capacity in plants
-
Gillespie K.M., Chae J.M., Ainsworth E.A. Rapid measurement of total antioxidant capacity in plants. Nat. Protoc 2007, 2:867-870.
-
(2007)
Nat. Protoc
, vol.2
, pp. 867-870
-
-
Gillespie, K.M.1
Chae, J.M.2
Ainsworth, E.A.3
-
8
-
-
15044348677
-
Coenzyme Q10 affects expression of genes involved in cell signalling, metabolism and transport in human CaCo-2 cells
-
Groneberg D.A., Kindermann B., Althammer M., Klapper M., Vormann J., Littarru G.P., Döring F. Coenzyme Q10 affects expression of genes involved in cell signalling, metabolism and transport in human CaCo-2 cells. Int. J. Biochem. Cell Biol. 2005, 37:1208-1218.
-
(2005)
Int. J. Biochem. Cell Biol.
, vol.37
, pp. 1208-1218
-
-
Groneberg, D.A.1
Kindermann, B.2
Althammer, M.3
Klapper, M.4
Vormann, J.5
Littarru, G.P.6
Döring, F.7
-
9
-
-
0032585818
-
Oxidative stress and neural dysfunction in Down syndrome
-
Iannello R.C., Crack P.J., de Haan J.B., Kola I. Oxidative stress and neural dysfunction in Down syndrome. J. Neural Transm. Suppl 1999, 57:257-267.
-
(1999)
J. Neural Transm. Suppl
, vol.57
, pp. 257-267
-
-
Iannello, R.C.1
Crack, P.J.2
de Haan, J.B.3
Kola, I.4
-
10
-
-
0032401643
-
Biomarkers of oxidative stress are significantly elevated in Down syndrome
-
Jovanovic S.V., Clements D., MacLeod K. Biomarkers of oxidative stress are significantly elevated in Down syndrome. Free Radic. Biol. Med 1998, 25:1044-1048.
-
(1998)
Free Radic. Biol. Med
, vol.25
, pp. 1044-1048
-
-
Jovanovic, S.V.1
Clements, D.2
MacLeod, K.3
-
11
-
-
10644277149
-
Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis
-
Lim P., Wuenschell G.E., Holland V., Lee D.H., Pfeifer G.P., Rodriguez H., Termini J. Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis. Biochemistry 2004, 43:15339-15348.
-
(2004)
Biochemistry
, vol.43
, pp. 15339-15348
-
-
Lim, P.1
Wuenschell, G.E.2
Holland, V.3
Lee, D.H.4
Pfeifer, G.P.5
Rodriguez, H.6
Termini, J.7
-
12
-
-
75749150806
-
Clinical aspects of coenzyme Q10: an update
-
Littarru G.P., Tiano L. Clinical aspects of coenzyme Q10: an update. Nutrition 2010, 26:250-254.
-
(2010)
Nutrition
, vol.26
, pp. 250-254
-
-
Littarru, G.P.1
Tiano, L.2
-
13
-
-
53849091350
-
Biomarkers of oxidative damage to DNA and repair
-
Loft S., Høgh Danielsen P., Mikkelsen L., Risom L., Forchhammer L., Møller P. Biomarkers of oxidative damage to DNA and repair. Biochem. Soc. Trans 2008, 36:1071-1076.
-
(2008)
Biochem. Soc. Trans
, vol.36
, pp. 1071-1076
-
-
Loft, S.1
Høgh Danielsen, P.2
Mikkelsen, L.3
Risom, L.4
Forchhammer, L.5
Møller, P.6
-
14
-
-
0035140477
-
Genomic instability in Down syndrome and Fanconi anemia assessed by micronucleus analysis and single-cell gel electrophoresis
-
Maluf S.W., Erdtmann B. Genomic instability in Down syndrome and Fanconi anemia assessed by micronucleus analysis and single-cell gel electrophoresis. Cancer Genet. Cytogenet 2001, 124:71-75.
-
(2001)
Cancer Genet. Cytogenet
, vol.124
, pp. 71-75
-
-
Maluf, S.W.1
Erdtmann, B.2
-
15
-
-
36049028290
-
Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy
-
37
-
Miles M.V., Patterson B.J., Chalfonte-Evans M.L., Horn P.S., Hickey F.J., Schapiro M.B., Steele P.E., Tang P.H., Hotze S.L. Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy. Pediatr. Neurol 2007, 21:398-403. 37.
-
(2007)
Pediatr. Neurol
, vol.21
, pp. 398-403
-
-
Miles, M.V.1
Patterson, B.J.2
Chalfonte-Evans, M.L.3
Horn, P.S.4
Hickey, F.J.5
Schapiro, M.B.6
Steele, P.E.7
Tang, P.H.8
Hotze, S.L.9
-
16
-
-
37148999073
-
DNA damage and repair in children with Down's syndrome
-
Morawiec Z., Janik K., Kowalski M., Stetkiewicz T., Szaflik J., Morawiec-Bajda A., Sobczuk A., Blasiak J. DNA damage and repair in children with Down's syndrome. Mutat. Res 2008, 637:118-123.
-
(2008)
Mutat. Res
, vol.637
, pp. 118-123
-
-
Morawiec, Z.1
Janik, K.2
Kowalski, M.3
Stetkiewicz, T.4
Szaflik, J.5
Morawiec-Bajda, A.6
Sobczuk, A.7
Blasiak, J.8
-
17
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A., Perry G., Aliev G., Hirai K., Takeda A., Balraj E.K., Jones P.K., Ghanbari H., Wataya T., Shimohama S., Chiba S., Atwood C.S., Petersen R.B., Smith M.A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol 2001, 60:759-767.
-
(2001)
J. Neuropathol. Exp. Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
18
-
-
33747256270
-
Multiple evidence for an early age pro-oxidant state in Down Syndrome patients
-
Pallardó F.V., Degan P., d'Ischia M., Kelly F.J., Zatterale A., Calzone R., Castello G., Fernandez-Delgado R., Dunster C., Lloret A., Manini P., Pisanti M.A., Vuttariello E., Pagano G. Multiple evidence for an early age pro-oxidant state in Down Syndrome patients. Biogerontology 2006, 7:211-220.
-
(2006)
Biogerontology
, vol.7
, pp. 211-220
-
-
Pallardó, F.V.1
Degan, P.2
d'Ischia, M.3
Kelly, F.J.4
Zatterale, A.5
Calzone, R.6
Castello, G.7
Fernandez-Delgado, R.8
Dunster, C.9
Lloret, A.10
Manini, P.11
Pisanti, M.A.12
Vuttariello, E.13
Pagano, G.14
-
19
-
-
0032945331
-
Effect of vitamin E on chromosomal aberrations in lymphocytes from patients with Down's syndrome
-
Pincheira J., Navarrete M.H., de la Torre C., Tapia G., Santos M.J. Effect of vitamin E on chromosomal aberrations in lymphocytes from patients with Down's syndrome. Clin. Genet 1999, 55:192-197.
-
(1999)
Clin. Genet
, vol.55
, pp. 192-197
-
-
Pincheira, J.1
Navarrete, M.H.2
de la Torre, C.3
Tapia, G.4
Santos, M.J.5
-
20
-
-
0032509749
-
Trisomy 21 and accelerated aging: DNA-repair parameters in peripheral lymphocytes of Down's syndrome patients
-
Raji N.S., Rao K.S. Trisomy 21 and accelerated aging: DNA-repair parameters in peripheral lymphocytes of Down's syndrome patients. Mech. Ageing Dev 1998, 100:85-101.
-
(1998)
Mech. Ageing Dev
, vol.100
, pp. 85-101
-
-
Raji, N.S.1
Rao, K.S.2
-
21
-
-
34648828494
-
Functional connections and pathways of coenzyme Q10-inducible genes: an in-silico study
-
Schmelzer C., Lindner I., Vock C., Fujii K., Döring F. Functional connections and pathways of coenzyme Q10-inducible genes: an in-silico study. IUBMB Life 2007, 59:628-633.
-
(2007)
IUBMB Life
, vol.59
, pp. 628-633
-
-
Schmelzer, C.1
Lindner, I.2
Vock, C.3
Fujii, K.4
Döring, F.5
-
22
-
-
0031576357
-
Evidence against increased oxidative DNA-damage in Down syndrome
-
Seidl R., Greber S., Schuller E., Bernert G., Cairns N., Lubec G. Evidence against increased oxidative DNA-damage in Down syndrome. Neurosci. Lett 1997, 17:137-140.
-
(1997)
Neurosci. Lett
, vol.17
, pp. 137-140
-
-
Seidl, R.1
Greber, S.2
Schuller, E.3
Bernert, G.4
Cairns, N.5
Lubec, G.6
-
23
-
-
33746069330
-
Estimation of plasma and saliva levels of coenzyme Q10 and influence of oral supplementation
-
Sekine K., Ota N., Nishii M., Uetake T., Shimadzu M. Estimation of plasma and saliva levels of coenzyme Q10 and influence of oral supplementation. Biofactors 2005, 25:205-211.
-
(2005)
Biofactors
, vol.25
, pp. 205-211
-
-
Sekine, K.1
Ota, N.2
Nishii, M.3
Uetake, T.4
Shimadzu, M.5
-
24
-
-
33947168891
-
Mechanisms of disease: DNA repair defects and neurological disease
-
Subba Rao K. Mechanisms of disease: DNA repair defects and neurological disease. Nat. Clin. Pract. Neurol 2007, 3:162-172.
-
(2007)
Nat. Clin. Pract. Neurol
, vol.3
, pp. 162-172
-
-
Subba Rao, K.1
-
25
-
-
51249120293
-
The mitochondrial cocktail: rationale for combined nutraceutical therapy in mitochondrial cytopathies
-
Tarnopolsky M.A. The mitochondrial cocktail: rationale for combined nutraceutical therapy in mitochondrial cytopathies. Adv. Drug Deliv. Rev 2008, 60:1561-1567.
-
(2008)
Adv. Drug Deliv. Rev
, vol.60
, pp. 1561-1567
-
-
Tarnopolsky, M.A.1
-
26
-
-
80052630069
-
Effect of Coenzyme Q(10) in mitigating oxidative DNA damage in Down syndrome patients, a double blind randomized controlled trial
-
Tiano L., Carnevali P., Padella L., Santoro L., Principi F., Brugè F., Carle F., Gesuita R., Gabrielli O., Littarru G.P. Effect of Coenzyme Q(10) in mitigating oxidative DNA damage in Down syndrome patients, a double blind randomized controlled trial. Neurobiol. Aging 2009, 10.1016/j.neurobiolaging.2009.11.016.
-
(2009)
Neurobiol. Aging
-
-
Tiano, L.1
Carnevali, P.2
Padella, L.3
Santoro, L.4
Principi, F.5
Brugè, F.6
Carle, F.7
Gesuita, R.8
Gabrielli, O.9
Littarru, G.P.10
-
27
-
-
0035378494
-
In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage
-
Tomasetti M., Alleva R., Borghi B., Collins A.R. In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage. FASEB J 2001, 15:1425-1427.
-
(2001)
FASEB J
, vol.15
, pp. 1425-1427
-
-
Tomasetti, M.1
Alleva, R.2
Borghi, B.3
Collins, A.R.4
-
28
-
-
33847349325
-
Oxidative stress: a bridge between Down's syndrome and Alzheimer's disease
-
Zana M., Janka Z., Kálmán J. Oxidative stress: a bridge between Down's syndrome and Alzheimer's disease. Neurobiol. Aging 2007, 28:648-676.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 648-676
-
-
Zana, M.1
Janka, Z.2
Kálmán, J.3
-
29
-
-
33646905061
-
Age-dependent oxidative stress-induced DNA damage in Down's lymphocytes
-
Zana M., Szécsényi A., Czibula A., Bjelik A., Juhász A., Rimanóczy A., Szabó K., Vetró A., Szucs P., Várkonyi A., Pákáski M., Boda K., Raskó I., Janka Z., Kálmán J. Age-dependent oxidative stress-induced DNA damage in Down's lymphocytes. Biochem. Biophys. Res. Commun 2006, 345:726-733.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.345
, pp. 726-733
-
-
Zana, M.1
Szécsényi, A.2
Czibula, A.3
Bjelik, A.4
Juhász, A.5
Rimanóczy, A.6
Szabó, K.7
Vetró, A.8
Szucs, P.9
Várkonyi, A.10
Pákáski, M.11
Boda, K.12
Raskó, I.13
Janka, Z.14
Kálmán, J.15
|