-
1
-
-
0033393822
-
Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart
-
doi:10.1172/JCI7605
-
Abel ED, Kaulbach HC, Tian R, Hopkins JC, Duffy J, Doetschman T, Minnemann T, Boers ME, Hadro E, Oberste-Berghaus C et al. 1999 Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. Journal of Clinical Investigation 104 1703-1714. (doi:10.1172/JCI7605)
-
(1999)
Journal of Clinical Investigation
, vol.104
, pp. 1703-1714
-
-
Abel, E.D.1
Kaulbach, H.C.2
Tian, R.3
Hopkins, J.C.4
Duffy, J.5
Doetschman, T.6
Minnemann, T.7
Boers, M.E.8
Hadro, E.9
Oberste-Berghaus, C.10
-
2
-
-
27844460627
-
Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess
-
doi:10.1074/jbc.M506967200
-
Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S et al. 2005 Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess. Journal of Biological Chemistry 280 37489-37494. (doi:10.1074/jbc.M506967200)
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 37489-37494
-
-
Barbour, L.A.1
Mizanoor Rahman, S.2
Gurevich, I.3
Leitner, J.W.4
Fischer, S.J.5
Roper, M.D.6
Knotts, T.A.7
Vo, Y.8
McCurdy, C.E.9
Yakar, S.10
-
3
-
-
0242490056
-
Can growth hormone (GH) accelerate aging? Evidence from GH-transgenic mice
-
doi:10.1159/000073704
-
Bartke A 2003 Can growth hormone (GH) accelerate aging? Evidence from GH-transgenic mice Neuroendocrinology 78 210-216. (doi:10.1159/000073704)
-
(2003)
Neuroendocrinology
, vol.78
, pp. 210-216
-
-
Bartke, A.1
-
4
-
-
23844551318
-
Minireview: Role of the growth hormone/insulinlike growth factor system in mammalian aging
-
doi:10.1210/en.2005-0411
-
Bartke A 2005 Minireview: role of the growth hormone/insulinlike growth factor system in mammalian aging. Endocrinology 146 3718-3723. (doi:10.1210/en.2005-0411)
-
(2005)
Endocrinology
, vol.146
, pp. 3718-3723
-
-
Bartke, A.1
-
5
-
-
0036192939
-
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression
-
doi:10.1172/JCI13946
-
Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE et al. 2002 Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. Journal of Clinical Investigation 109 629-639. (doi:10.1172/JCI13946)
-
(2002)
Journal of Clinical Investigation
, vol.109
, pp. 629-639
-
-
Belke, D.D.1
Betuing, S.2
Tuttle, M.J.3
Graveleau, C.4
Young, M.E.5
Pham, M.6
Zhang, D.7
Cooksey, R.C.8
McClain, D.A.9
Litwin, S.E.10
-
7
-
-
17744363431
-
Impairment of cardiac function and bioenergetics in adult transgenic mice overexpressing the bovine growth hormone gene
-
doi:10.1210/en.141.6.2229
-
Bollano E, Omerovic E, Bohlooly-y M, Kujacic V, Madhu B, Törnell J, Isaksson O, Soussi B, Schulze W, Fu ML et al. 2000 Impairment of cardiac function and bioenergetics in adult transgenic mice overexpressing the bovine growth hormone gene. Endocrinology 141 2229-2235. (doi:10.1210/en.141.6.2229)
-
(2000)
Endocrinology
, vol.141
, pp. 2229-2235
-
-
Bollano, E.1
Omerovic, E.2
Bohlooly-Y, M.3
Kujacic, V.4
Madhu, B.5
Törnell, J.6
Isaksson, O.7
Soussi, B.8
Schulze, W.9
Fu, M.L.10
-
8
-
-
78049387191
-
Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: A cross-sectional analysis
-
doi:10.1515/BC.2010.124
-
Boparai RK, Arum O, Khardori R & Bartke A 2010 Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis. Biological Chemistry 391 1149-1155. (doi:10.1515/BC.2010.124)
-
(2010)
Biological Chemistry
, vol.391
, pp. 1149-1155
-
-
Boparai, R.K.1
Arum, O.2
Khardori, R.3
Bartke, A.4
-
9
-
-
65649098029
-
Phosphorylation of IRS proteins, insulin action, and insulin resistance
-
doi:10.1152/ajpendo. 90437.2008
-
Boura-Halfon S & Zick Y 2009 Phosphorylation of IRS proteins, insulin action, and insulin resistance. American Journal of Physiology. Endocrinology and Metabolism 296 E581-E591. (doi:10.1152/ajpendo. 90437.2008)
-
(2009)
American Journal of Physiology. Endocrinology and Metabolism
, vol.296
-
-
Boura-Halfon, S.1
Zick, Y.2
-
10
-
-
0027436767
-
Regulation of glucose transporter and hexokinase II expression in tissues of diabetic rats
-
Burcelin R, Printz RL, Kande J, Assan R, Granner DK & Girard J 1993 Regulation of glucose transporter and hexokinase II expression in tissues of diabetic rats. American Journal of Physiology 265 E392-E401.
-
(1993)
American Journal of Physiology
, vol.265
-
-
Burcelin, R.1
Printz, R.L.2
Kande, J.3
Assan, R.4
Granner, D.K.5
Girard, J.6
-
11
-
-
20644434143
-
Cross-talk between the insulin and leptin signaling systems in rat hypothalamus
-
doi:10.1038/oby.2005.7
-
Carvalheira JB, Torsoni MA, Ueno M, Amaral ME, Araújo EP, Velloso LA, Gontijo JA & Saad MJ 2005 Cross-talk between the insulin and leptin signaling systems in rat hypothalamus. Obesity Research 13 48-57. (doi:10.1038/oby.2005.7)
-
(2005)
Obesity Research
, vol.13
, pp. 48-57
-
-
Carvalheira, J.B.1
Torsoni, M.A.2
Ueno, M.3
Amaral, M.E.4
Araújo, E.P.5
Velloso, L.A.6
Gontijo, J.A.7
Saad, M.J.8
-
12
-
-
0033499415
-
Blood pressure-independent cardiac hypertrophy in acromegalic patients
-
doi:10.1097/00004872- 199917121-00028
-
Ciulla M, Arosio M, Barelli MV, Paliotti R, Porretti S, Valentini P, Tortora G, Buonamici V, Moraschi A, Capiello V et al. 1999 Blood pressure-independent cardiac hypertrophy in acromegalic patients. Journal of Hypertension 17 1965-1969. (doi:10.1097/00004872- 199917121-00028)
-
(1999)
Journal of Hypertension
, vol.17
, pp. 1965-1969
-
-
Ciulla, M.1
Arosio, M.2
Barelli, M.V.3
Paliotti, R.4
Porretti, S.5
Valentini, P.6
Tortora, G.7
Buonamici, V.8
Moraschi, A.9
Capiello, V.10
-
13
-
-
34250155671
-
Pharmacologic therapy in growth hormone disorders and the heart
-
doi:10.2174/092986707780831195
-
Climent V, Marín F & Picó A 2007 Pharmacologic therapy in growth hormone disorders and the heart. Current Medicinal Chemistry 14 1399-1407. (doi:10.2174/092986707780831195)
-
(2007)
Current Medicinal Chemistry
, vol.14
, pp. 1399-1407
-
-
Climent, V.1
Marín, F.2
Picó, A.3
-
14
-
-
49649106996
-
The GH-IGF-I axis and the cardiovascular system: Clinical implications
-
doi:10. 1111/j.1365-2265.2008.03292.x
-
Colao A 2008 The GH-IGF-I axis and the cardiovascular system: clinical implications. Clinical Endocrinology 69 347-358. (doi:10. 1111/j.1365-2265.2008.03292.x)
-
(2008)
Clinical Endocrinology
, vol.69
, pp. 347-358
-
-
Colao, A.1
-
15
-
-
0036098869
-
Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice
-
doi:10.1677/joe.0.1730257
-
Colligan PB, Brown-Borg HM, Duan J, Ren BH & Ren J 2002 Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice. Journal of Endocrinology 173 257-264. (doi:10.1677/joe.0.1730257)
-
(2002)
Journal of Endocrinology
, vol.173
, pp. 257-264
-
-
Colligan, P.B.1
Brown-Borg, H.M.2
Duan, J.3
Ren, B.H.4
Ren, J.5
-
16
-
-
34248664707
-
Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters
-
doi:10.1007/s11010-005-9030-5
-
Coort SL, Bonen A, van der Vusse GJ, Glatz JF & Luiken JJ 2007 Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: role of sarcolemmal substrate transporters. Molecular and Cellular Biochemistry 299 5-18. (doi:10.1007/s11010-005-9030-5)
-
(2007)
Molecular and Cellular Biochemistry
, vol.299
, pp. 5-18
-
-
Coort, S.L.1
Bonen, A.2
van der Vusse, G.J.3
Glatz, J.F.4
Luiken, J.J.5
-
17
-
-
0034455827
-
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
-
doi:10.1210/ en.141.7.2608
-
Coschigano KT, Clemmons D, Bellush LL & Kopchick JJ 2000 Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 141 2608-2613. (doi:10.1210/ en.141.7.2608)
-
(2000)
Endocrinology
, vol.141
, pp. 2608-2613
-
-
Coschigano, K.T.1
Clemmons, D.2
Bellush, L.L.3
Kopchick, J.J.4
-
18
-
-
34249679614
-
MTOR complex1-S6K1 signaling: At the crossroads of obesity, diabetes and cancer
-
doi:10.1016/j.molmed.2007.04. 002
-
Dann SG, Selvaraj A & Thomas G 2007 mTOR complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer. Trends in Molecular Medicine 13 252-259. (doi:10.1016/j.molmed.2007.04. 002)
-
(2007)
Trends in Molecular Medicine
, vol.13
, pp. 252-259
-
-
Dann, S.G.1
Selvaraj, A.2
Thomas, G.3
-
19
-
-
42749094854
-
Insulin signaling pathways and cardiac growth
-
doi:10.1016/j.yjmcc.2008.03.008
-
DeBosch BJ & Muslin AJ 2008 Insulin signaling pathways and cardiac growth. Journal of Molecular and Cellular Cardiology 44 855-864. (doi:10.1016/j.yjmcc.2008.03.008)
-
(2008)
Journal of Molecular and Cellular Cardiology
, vol.44
, pp. 855-864
-
-
Debosch, B.J.1
Muslin, A.J.2
-
20
-
-
0031722221
-
Role of hyperinsulinemia on hepatic insulin receptor concentration and autophosphorylation in the presence of high growth hormone levels in transgenic mice overexpressing growth hormone gene
-
doi:10.1677/joe.0.1590015
-
Dominici FP, Balbis A, Bartke A & Turyn D 1998 Role of hyperinsulinemia on hepatic insulin receptor concentration and autophosphorylation in the presence of high growth hormone levels in transgenic mice overexpressing growth hormone gene. Journal of Endocrinology 159 15-25. (doi:10.1677/joe.0.1590015)
-
(1998)
Journal of Endocrinology
, vol.159
, pp. 15-25
-
-
Dominici, F.P.1
Balbis, A.2
Bartke, A.3
Turyn, D.4
-
21
-
-
0033037104
-
Loss of sensitivity to insulin at early events of the insulin signaling pathway in the liver of growth hormone-transgenic mice
-
doi:10.1677/joe.0.1610383
-
Dominici FP, Cifone D, Bartke A & Turyn D 1999a Loss of sensitivity to insulin at early events of the insulin signaling pathway in the liver of growth hormone-transgenic mice. Journal of Endocrinology 161 383-392. (doi:10.1677/joe.0.1610383)
-
(1999)
Journal of Endocrinology
, vol.161
, pp. 383-392
-
-
Dominici, F.P.1
Cifone, D.2
Bartke, A.3
Turyn, D.4
-
22
-
-
0032883443
-
Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice
-
Dominici FP, Cifone D, Bartke A & Turyn D 1999b Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice. American Journal of Physiology 277 E447-E454.
-
(1999)
American Journal of Physiology
, vol.277
-
-
Dominici, F.P.1
Cifone, D.2
Bartke, A.3
Turyn, D.4
-
23
-
-
0033835911
-
Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice
-
doi:10.1677/joe.0.1660579
-
Dominici FP, Arostegui Diaz G, Bartke A, Kopchick JJ & Turyn D 2000 Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice. Journal of Endocrinology 166 579-590. (doi:10.1677/joe.0.1660579)
-
(2000)
Journal of Endocrinology
, vol.166
, pp. 579-590
-
-
Dominici, F.P.1
Arostegui Diaz, G.2
Bartke, A.3
Kopchick, J.J.4
Turyn, D.5
-
24
-
-
26044464801
-
Influence of the crosstalk between growth hormone and insulin signalling on the modulation of insulin sensitivity
-
doi:10.1016/j.ghir. 2005.07.001
-
Dominici FP, Argentino DP, Muñoz MC, Miquet JG, Sotelo AI & Turyn D 2005 Influence of the crosstalk between growth hormone and insulin signalling on the modulation of insulin sensitivity. Growth Hormone & IGF Research 15 324-336. (doi:10.1016/j.ghir. 2005.07.001)
-
(2005)
Growth Hormone & IGF Research
, vol.15
, pp. 324-336
-
-
Dominici, F.P.1
Argentino, D.P.2
Muñoz, M.C.3
Miquet, J.G.4
Sotelo, A.I.5
Turyn, D.6
-
25
-
-
33749342069
-
Molecular mechanisms of insulin resistance: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: The two sides of a coin
-
doi:10.2337/db06-0391
-
Draznin B 2006 Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin. Diabetes 55 2392-2397. (doi:10.2337/db06-0391)
-
(2006)
Diabetes
, vol.55
, pp. 2392-2397
-
-
Draznin, B.1
-
26
-
-
0027412571
-
Effects of diabetes on myocardial glucose transport system in rats: Implications for diabetic cardiomyopathy
-
Garvey WT, Hardin D, Juhaszova M & Dominguez JH 1993 Effects of diabetes on myocardial glucose transport system in rats: implications for diabetic cardiomyopathy. American Journal of Physiology 264 H837-H844.
-
(1993)
American Journal of Physiology
, vol.264
-
-
Garvey, W.T.1
Hardin, D.2
Juhaszova, M.3
Dominguez, J.H.4
-
27
-
-
53349089561
-
Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: Effects of calorie restriction
-
Giani JF, Bonkowski MS, Muñoz MC, Masternak MM, Turyn D, Bartke A & Dominici FP 2008 Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of calorie restriction. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 63 788-797.
-
(2008)
Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
, vol.63
, pp. 788-797
-
-
Giani, J.F.1
Bonkowski, M.S.2
Muñoz, M.C.3
Masternak, M.M.4
Turyn, D.5
Bartke, A.6
Dominici, F.P.7
-
28
-
-
0344686538
-
MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632
-
doi:10.1007/s00125-003- 1223-4
-
Gual P, Grémeaux T, Gonzalez T, Le Marchand-Brustel Y & Tanti JF 2003 MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632. Diabetologia 46 1532-1542. (doi:10.1007/s00125-003- 1223-4)
-
(2003)
Diabetologia
, vol.46
, pp. 1532-1542
-
-
Gual, P.1
Grémeaux, T.2
Gonzalez, T.3
Le Marchand-Brustel, Y.4
Tanti, J.F.5
-
29
-
-
70349348922
-
The cardiovascular phenotype of a mouse model of acromegaly
-
doi:10.1016/j.ghir.2008.12.006
-
Izzard AS, Emerson M, Prehar S, Neyses L, Trainer P, List EO, Kopchick JJ & Heagerty AM 2009 The cardiovascular phenotype of a mouse model of acromegaly. Growth Hormone & IGF Research 19 413-419. (doi:10.1016/j.ghir.2008.12.006)
-
(2009)
Growth Hormone & IGF Research
, vol.19
, pp. 413-419
-
-
Izzard, A.S.1
Emerson, M.2
Prehar, S.3
Neyses, L.4
Trainer, P.5
List, E.O.6
Kopchick, J.J.7
Heagerty, A.M.8
-
30
-
-
0029148426
-
Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4
-
doi:10.1038/377151a0
-
Katz EB, Stenbit AE, Hatton K, DePinho R & Charron MJ 1995 Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4. Nature 377 151-155. (doi:10.1038/377151a0)
-
(1995)
Nature
, vol.377
, pp. 151-155
-
-
Katz, E.B.1
Stenbit, A.E.2
Hatton, K.3
Depinho, R.4
Charron, M.J.5
-
32
-
-
4143085927
-
Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice
-
doi:10.1152/ajpendo.00423.2003
-
Liu JL, Coschigano KT, Robertson K, Lipsett M, Guo Y, Kopchick JJ, Kumar U & Liu YL 2004 Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. American Journal of Physiology. Endocrinology and Metabolism 287 E405-E413. (doi:10.1152/ajpendo.00423.2003)
-
(2004)
American Journal of Physiology. Endocrinology and Metabolism
, vol.287
-
-
Liu, J.L.1
Coschigano, K.T.2
Robertson, K.3
Lipsett, M.4
Guo, Y.5
Kopchick, J.J.6
Kumar, U.7
Liu, Y.L.8
-
33
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man
-
doi:10.1007/ BF00280883
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC 1985 Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 412-419. (doi:10.1007/ BF00280883)
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
34
-
-
0025609617
-
Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice
-
McGrane MM, Yun JS, Moorman AF, Lamers WH, Hendrick GK, Arafah BM, Park EA, Wagner TE & Hanson RW 1990 Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice. Journal of Biological Chemistry 265 22371-22379.
-
(1990)
Journal of Biological Chemistry
, vol.265
, pp. 22371-22379
-
-
McGrane, M.M.1
Yun, J.S.2
Moorman, A.F.3
Lamers, W.H.4
Hendrick, G.K.5
Arafah, B.M.6
Park, E.A.7
Wagner, T.E.8
Hanson, R.W.9
-
35
-
-
65249171425
-
Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects
-
doi:10.1210/er.2008-0027
-
Møller N & Jørgensen JO 2009 Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocrine Reviews 30 152-177. (doi:10.1210/er.2008-0027)
-
(2009)
Endocrine Reviews
, vol.30
, pp. 152-177
-
-
Møller, N.1
Jørgensen, J.O.2
-
37
-
-
53449097061
-
MAPK signalling in cardiovascular health and disease: Molecular mechanisms and therapeutic targets
-
doi:10.1042/CS20070430
-
Muslin AJ 2008 MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets. Clinical Science 115 203-218. (doi:10.1042/CS20070430)
-
(2008)
Clinical Science
, vol.115
, pp. 203-218
-
-
Muslin, A.J.1
-
39
-
-
3242793344
-
Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy
-
doi:10.1016/ j.cardiores.2004.02.003
-
Proud CG 2004 Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy. Cardiovascular Research 63 403-413. (doi:10.1016/ j.cardiores.2004.02.003)
-
(2004)
Cardiovascular Research
, vol.63
, pp. 403-413
-
-
Proud, C.G.1
-
40
-
-
0021906772
-
Production of insulin resistance by hyperinsulinemia in man
-
Rizza RA, Mandarino LJ, Genest J, Baker BA & Gerich JE 1985 Production of insulin resistance by hyperinsulinemia in man. Diabetologia 28 70-75.
-
(1985)
Diabetologia
, vol.28
, pp. 70-75
-
-
Rizza, R.A.1
Mandarino, L.J.2
Genest, J.3
Baker, B.A.4
Gerich, J.E.5
-
41
-
-
0345171012
-
Growth hormone, acromegaly, and heart failure: An intricate triangulation
-
doi:10.1046/j.1365-2265.2003.01780.x
-
Saccà L, Napoli R & Cittadini A 2003 Growth hormone, acromegaly, and heart failure: an intricate triangulation. Clinical Endocrinology 59 660-671. (doi:10.1046/j.1365-2265.2003.01780.x)
-
(2003)
Clinical Endocrinology
, vol.59
, pp. 660-671
-
-
Saccà, L.1
Napoli, R.2
Cittadini, A.3
-
42
-
-
0026543026
-
Glucose transporter levels in tissues of spontaneously diabetic Zucker fa/fa rat (ZDF/drt) and viable yellow mouse (Avy/a)
-
doi:10.2337/diabetes. 41.2.187
-
Slieker LJ, Sundell KL, Heath WF, Osborne HE, Bue J, Manetta J & Sportsman JR 1992 Glucose transporter levels in tissues of spontaneously diabetic Zucker fa/fa rat (ZDF/drt) and viable yellow mouse (Avy/a). Diabetes 41 187-193. (doi:10.2337/diabetes. 41.2.187)
-
(1992)
Diabetes
, vol.41
, pp. 187-193
-
-
Slieker, L.J.1
Sundell, K.L.2
Heath, W.F.3
Osborne, H.E.4
Bue, J.5
Manetta, J.6
Sportsman, J.R.7
-
43
-
-
16844370268
-
Regulation of insulin signalling by hyperinsulinaemia: Role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
-
doi:10.1007/s00125-004-1662-6
-
Ueno M, Carvalheira JB, Tambascia RC, Bezerra RM, Amaral ME, Carneiro EM, Folli F, Franchini KG & Saad MJ 2005 Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 48 506-518. (doi:10.1007/s00125-004-1662-6)
-
(2005)
Diabetologia
, vol.48
, pp. 506-518
-
-
Ueno, M.1
Carvalheira, J.B.2
Tambascia, R.C.3
Bezerra, R.M.4
Amaral, M.E.5
Carneiro, E.M.6
Folli, F.7
Franchini, K.G.8
Saad, M.J.9
-
44
-
-
0027231548
-
Glucose metabolism in transgenic mice containing a chimeric P-enolpyruvate carboxykinase/bovine growth hormone gene
-
Valera A, Rodriguez-Gil JE, Yun JS, McGrane MM, Hanson RW & Bosch F 1993 Glucose metabolism in transgenic mice containing a chimeric P-enolpyruvate carboxykinase/bovine growth hormone gene. FASEB Journal 7 791-800.
-
(1993)
FASEB Journal
, vol.7
, pp. 791-800
-
-
Valera, A.1
Rodriguez-Gil, J.E.2
Yun, J.S.3
McGrane, M.M.4
Hanson, R.W.5
Bosch, F.6
-
45
-
-
66149118127
-
Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice
-
doi:10.1152/ajpendo.00054.2009
-
Vieira VJ, Valentine RJ, Wilund KR, Antao N, Baynard T & Woods JA 2009 Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice. American Journal of Physiology. Endocrinology and Metabolism 296 E1164-E1171. (doi:10.1152/ajpendo.00054.2009)
-
(2009)
American Journal of Physiology. Endocrinology and Metabolism
, vol.296
-
-
Vieira, V.J.1
Valentine, R.J.2
Wilund, K.R.3
Antao, N.4
Baynard, T.5
Woods, J.A.6
-
46
-
-
0033756825
-
Role of growth hormone in chronic heart failure. Therapeutic implications
-
doi:10.2165/00003495-200060040-00002
-
Volterrani M, Manelli F, Cicoira M, Lorusso R & Giustina A 2000 Role of growth hormone in chronic heart failure. Therapeutic implications. Drugs 60 711-719. (doi:10.2165/00003495-200060040-00002)
-
(2000)
Drugs
, vol.60
, pp. 711-719
-
-
Volterrani, M.1
Manelli, F.2
Cicoira, M.3
Lorusso, R.4
Giustina, A.5
-
47
-
-
34548695952
-
Mitogen-activated protein kinases in heart development and diseases
-
doi:10.1161/CIRCULATIONAHA. C106.679589
-
Wang Y 2007 Mitogen-activated protein kinases in heart development and diseases. Circulation 116 1413-1423. (doi:10.1161/CIRCULATIONAHA. C106.679589)
-
(2007)
Circulation
, vol.116
, pp. 1413-1423
-
-
Wang, Y.1
-
48
-
-
61349161849
-
Crosstalk between growth hormone and insulin signaling
-
doi:10.1016/ S0083-6729(08)00606-7
-
Xu J & Messina JL 2009 Crosstalk between growth hormone and insulin signaling. Vitamins and Hormones 80 125-153. (doi:10.1016/ S0083-6729(08)00606-7)
-
(2009)
Vitamins and Hormones
, vol.80
, pp. 125-153
-
-
Xu, J.1
Messina, J.L.2
-
49
-
-
77749286358
-
Insulin signaling: A possible pathogenesis of cardiac hypertrophy
-
doi:10.1111/j.1755-5922.2009.00120.x
-
Yu W, Chen C, Fu Y, Wang X & Wang W 2010 Insulin signaling: a possible pathogenesis of cardiac hypertrophy. Cardiovascular Therapeutics 28 101-105. (doi:10.1111/j.1755-5922.2009.00120.x)
-
(2010)
Cardiovascular Therapeutics
, vol.28
, pp. 101-105
-
-
Yu, W.1
Chen, C.2
Fu, Y.3
Wang, X.4
Wang, W.5
-
50
-
-
12744268367
-
Rosiglitazone treatment in Zucker diabetic fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion-induced myocardial injury
-
doi:10.2337/diabetes.54.2.554
-
Yue TL, Bao W, Gu JL, Cui J, Tao L, Ma XL, Ohlstein EH & Jucker BM 2005 Rosiglitazone treatment in Zucker diabetic fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion-induced myocardial injury. Diabetes 54 554-562. (doi:10.2337/diabetes.54.2.554)
-
(2005)
Diabetes
, vol.54
, pp. 554-562
-
-
Yue, T.L.1
Bao, W.2
Gu, J.L.3
Cui, J.4
Tao, L.5
Ma, X.L.6
Ohlstein, E.H.7
Jucker, B.M.8
-
51
-
-
12644257576
-
Amammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
-
doi:10.1073/pnas.94.24.13215
-
Zhou Y, Xu BC, Maheshwari HG, He L, Reed M, Lozykowski M, Okada S, Cataldo L, Coschigamo K, Wagner TE et al. 1997 Amammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). PNAS 94 13215-13220. (doi:10.1073/pnas.94.24.13215)
-
(1997)
PNAS
, vol.94
, pp. 13215-13220
-
-
Zhou, Y.1
Xu, B.C.2
Maheshwari, H.G.3
He, L.4
Reed, M.5
Lozykowski, M.6
Okada, S.7
Cataldo, L.8
Coschigamo, K.9
Wagner, T.E.10
-
52
-
-
0033834248
-
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance
-
doi:10.1038/78693
-
Zisman A, Peroni OD, Abel ED, Michael MD, Mauvais-Jarvis F, Lowell BB, Wojtaszewski JF, Hirshman MF, Virkamaki A, Goodyear LJ et al. 2000 Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. Nature Medicine 6 924-928. (doi:10.1038/78693)
-
(2000)
Nature Medicine
, vol.6
, pp. 924-928
-
-
Zisman, A.1
Peroni, O.D.2
Abel, E.D.3
Michael, M.D.4
Mauvais-Jarvis, F.5
Lowell, B.B.6
Wojtaszewski, J.F.7
Hirshman, M.F.8
Virkamaki, A.9
Goodyear, L.J.10
|