Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked Inhibitor of Apoptosis Protein (XIAP) to promote survival of Epstein-Barr Virus+(EBV+) B cell lymphomas

Journal of Biological Chemistry

Volumn 286, Issue 43, 2011, Pages 37368-37378

  Hatton, Olivia ^a   Phillips, Lori K ^a   Vaysberg, Maria ^a   Hurwich, Jordan ^a   Krams, Sheri M ^a   Martinez, Olivia M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL RECEPTOR; B CELLS; B-CELL LYMPHOMA; CASPASE INHIBITORS; CELL LINES; EPSTEIN-BARR VIRUS; INFECTED CELLS; LYMPHOMAGENESIS; PHOSPHATIDYLINOSITOL; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS; SMALL MOLECULES; THERAPEUTIC STRATEGY; THERAPEUTIC TARGETS; TUMOR PROGRESSIONS; X-LINKED INHIBITOR OF APOPTOSIS;

CELL CULTURE; CELL MEMBRANES; CELL PROLIFERATION; ENZYME INHIBITION; ONCOLOGY; SIGNALING; VIRUSES;

CELL DEATH;

INTERLEUKIN 10; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE SYK; SERINE PROTEINASE OMI; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LYMPHOPROLIFERATIVE DISEASE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; EPSTEIN-BARR VIRUS INFECTIONS; HERPESVIRUS 4, HUMAN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOMA, B-CELL; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIAL PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

HUMAN HERPESVIRUS 4;

EID: 80054805087     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.255125     Document Type: Article

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