Prediction of onset of crystallization in amorphous pharmaceutical systems: Phenobarbital, nifedipine/PVP, and phenobarbital/PVP

Journal of Pharmaceutical Sciences

Volumn 99, Issue 9, 2010, Pages 3887-3900

  Caron, Vincent ^a   Bhugra, Chandan ^b   Pikal, Michael J ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Amorphous; Crystallization; Glass transition; Mobility; Physical stability; Relaxation time; Solid dispersion; Solid state stability; Spectroscopy; Thermal analysis

Indexed keywords

NIFEDIPINE; PHENOBARBITAL; POVIDONE;

ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; GLASS TRANSITION TEMPERATURE; HIGH TEMPERATURE; ISOTHERMAL TITRATION CALORIMETRY; POLARIZATION MICROSCOPY; PREDICTION; SPECTROSCOPY; THERMOSTABILITY;

EID: 77956361367     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22232     Document Type: Article

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