Physicochemical and pharmacokinetic characterization of a spray-dried cefpodoxime proxetil nanosuspension

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 7, 2010, Pages 912-917

  Gao, Yuan ^a   Qian, Shuai ^b   Zhang, Jianjun ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Hong Kong Science Park   (Hong Kong)

Author keywords

Cefpodoxime proxetil; Nanosuspension; Pharmacokinetics; Rheological; Spray dried

Indexed keywords

CEFPODOXIME PROXETIL; HYDROXYPROPYLMETHYLCELLULOSE; LUTROL F68; METHYLCELLULOSE; POLOXAMER; PRODRUG; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; CEFTIZOXIME; NANOPARTICLE;

ADSORPTION; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DESORPTION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG SOLUBILITY; FLOW KINETICS; MALE; MEASUREMENT; MORPHOLOGY; NANOSUSPENSION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; POROSITY; RABBIT; SPRAY DRYING; SURFACE PROPERTY; SUSPENSION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; ORAL DRUG ADMINISTRATION; PHARMACEUTICS; PROCEDURES; ULTRASTRUCTURE;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; CEFTIZOXIME; MALE; NANOPARTICLES; PARTICLE SIZE; RABBITS; TECHNOLOGY, PHARMACEUTICAL;

EID: 77954268900     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.912     Document Type: Article

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