Altered gene expression in rat cranial neural crest cells exposed to a teratogenic glucose concentration in vitro-paradoxical downregulation of antioxidative defense genes

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 92, Issue 5, 2011, Pages 487-497

  Wentzel, Parri ^a   Eriksson, Ulf J ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Antioxidative enzymes; Gene expression; Glucose; Neural crest cells; Rat

Indexed keywords

ANTIOXIDANT; APC PROTEIN; BETA CATENIN; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUCOSE; GLUTATHIONE PEROXIDASE 1; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL 2; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX6; WNT3A PROTEIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ISOLATION; EMBRYO; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NEURAL CREST CELL; NONHUMAN; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOGENESIS;

ANIMALS; CELLS, CULTURED; DIABETES COMPLICATIONS; EMBRYO, MAMMALIAN; EYE PROTEINS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSE; HOMEODOMAIN PROTEINS; NEURAL CREST; PAIRED BOX TRANSCRIPTION FACTORS; PREGNANCY; PREGNANCY IN DIABETICS; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; RNA, MESSENGER; TERATOGENS; WNT SIGNALING PATHWAY;

RATTUS;

EID: 80054713675     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.20321     Document Type: Article

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