Exposure of neural crest cells to elevated glucose leads to congenital heart defects, an effect that can be prevented by N-acetylcysteine

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 79, Issue 3, 2007, Pages 231-235

  Roest, Pauline A M ^a   Van Iperen, Liesbeth ^a   Vis, Shirley ^a   Wisse, Lambertus J ^a   Poelmann, Rob E ^a   Steegers Theunissen, Regine P M ^b   Molin, Daniel G M ^c   Eriksson, Ulf J ^d   Gittenberger De Groot, Adriana C ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Antioxidants; Congenital heart disease; Elevated glucose; N acetylcysteine; Neural crest cells; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; GLUCOSE;

ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR MALFORMATION; CHICK EMBRYO; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; EXPOSURE; HEART DEVELOPMENT; IN VITRO STUDY; IN VIVO STUDY; NEURAL CREST CELL; NONHUMAN; PHARYNX; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROGENY; RISK FACTOR; TERATOGENICITY;

ACETYLCYSTEINE; ANIMALS; CHICK EMBRYO; GLUCOSE; HEART; HEART DEFECTS, CONGENITAL; NEURAL CREST;

EID: 33947103000     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.20341     Document Type: Article

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