메뉴 건너뛰기




Volumn 40, Issue 1, 1997, Pages 7-14

Teratogenic effect of diabetic serum is prevented by supplementation of superoxide dismutase and N-acetylcysteine in rat embryo culture

Author keywords

hydroxybutyrate; branched chain amino acids; congenital malformation; diabetic pregnancy; embryo culture; embryo development; glucose; N acetylcysteine; superoxide dismutase

Indexed keywords

3 HYDROXYBUTYRIC ACID; ACETYLCYSTEINE; GLUCOSE; SUPEROXIDE DISMUTASE;

EID: 0031023058     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050636     Document Type: Article
Times cited : (107)

References (42)
  • 2
    • 0020144915 scopus 로고
    • Malformations in infants of diabetic mothers
    • Mills JL (1982) Malformations in infants of diabetic mothers. Teratology 25: 385-394
    • (1982) Teratology , vol.25 , pp. 385-394
    • Mills, J.L.1
  • 4
    • 0028928950 scopus 로고
    • Correlations between maternal metabolism and deranged development in the offspring of normal and diabetic rats
    • Styrud J, Thunberg L, Nybacka O, Eriksson UJ (1995) Correlations between maternal metabolism and deranged development in the offspring of normal and diabetic rats. Pediatr Res 37: 343-353
    • (1995) Pediatr Res , vol.37 , pp. 343-353
    • Styrud, J.1    Thunberg, L.2    Nybacka, O.3    Eriksson, U.J.4
  • 5
    • 0017712779 scopus 로고
    • Teratogenic effects of excess glucose on head-fold rat embryos in culture
    • Cockroft DL, Coppola PT (1977) Teratogenic effects of excess glucose on head-fold rat embryos in culture. Teratology 16: 141-146
    • (1977) Teratology , vol.16 , pp. 141-146
    • Cockroft, D.L.1    Coppola, P.T.2
  • 6
    • 0020568967 scopus 로고
    • Effects of maternal diabetes on early embryogenesis. Alterations in morphogenesis produced by the ketone body β-hydroxybutyrate
    • Horton WE, Sadler TW (1983) Effects of maternal diabetes on early embryogenesis. Alterations in morphogenesis produced by the ketone body β-hydroxybutyrate. Diabetes 32: 610-616
    • (1983) Diabetes , vol.32 , pp. 610-616
    • Horton, W.E.1    Sadler, T.W.2
  • 7
    • 0029931302 scopus 로고    scopus 로고
    • Insulin treatment fails to abolish the teratogenic potential of serum from diabetic rats
    • Wentzel P, Eriksson UJ (1996) Insulin treatment fails to abolish the teratogenic potential of serum from diabetic rats. Eur J Endocrinol 134: 459-466
    • (1996) Eur J Endocrinol , vol.134 , pp. 459-466
    • Wentzel, P.1    Eriksson, U.J.2
  • 8
    • 0028216161 scopus 로고
    • Diabetic teratogenesis. In vitro evidence for a multifactorial aetiology with little contribution from glucose per se
    • Buchanan TA, Denno KM, Sipos GF, Sadler TW (1994) Diabetic teratogenesis. In vitro evidence for a multifactorial aetiology with little contribution from glucose per se. Diabetes 43: 656-660
    • (1994) Diabetes , vol.43 , pp. 656-660
    • Buchanan, T.A.1    Denno, K.M.2    Sipos, G.F.3    Sadler, T.W.4
  • 9
    • 0024592194 scopus 로고
    • Evidence for multifactorial origin of diabetes-induced embryopathies
    • Sadler TW, Hunter III ES, Wynn RE, Phillips LS (1989) Evidence for multifactorial origin of diabetes-induced embryopathies. Diabetes 38: 70-74
    • (1989) Diabetes , vol.38 , pp. 70-74
    • Sadler, T.W.1    Hunter III, E.S.2    Wynn, R.E.3    Phillips, L.S.4
  • 10
    • 0025868649 scopus 로고
    • Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitro
    • Eriksson UJ, Borg LAH (1991) Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitro. Diabetologia 34: 325-331
    • (1991) Diabetologia , vol.34 , pp. 325-331
    • Eriksson, U.J.1    Borg, L.A.H.2
  • 11
    • 0027394254 scopus 로고
    • Diabetes and embryonic malformations. Role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos
    • Eriksson UJ, Borg LAH (1993) Diabetes and embryonic malformations. Role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos. Diabetes 42: 411-419
    • (1993) Diabetes , vol.42 , pp. 411-419
    • Eriksson, U.J.1    Borg, L.A.H.2
  • 12
    • 0028899554 scopus 로고
    • Altered mitochondrial morphology of rat embryos in diabetic pregnancy
    • Yang X, Borg LAH, Eriksson UJ (1995) Altered mitochondrial morphology of rat embryos in diabetic pregnancy. Anat Rec 241: 255-267
    • (1995) Anat Rec , vol.241 , pp. 255-267
    • Yang, X.1    Borg, L.A.H.2    Eriksson, U.J.3
  • 13
    • 0023941164 scopus 로고
    • Importance of genetic predisposition and maternal environment for the occurrence of congenital malformations in offspring of diabetic rats
    • Eriksson UJ (1988) Importance of genetic predisposition and maternal environment for the occurrence of congenital malformations in offspring of diabetic rats. Teratology 37: 365-374
    • (1988) Teratology , vol.37 , pp. 365-374
    • Eriksson, U.J.1
  • 14
    • 0017928819 scopus 로고
    • Whole-embryo culture and the study of mammalian embryos during organogenesis
    • New DAT (1978) Whole-embryo culture and the study of mammalian embryos during organogenesis. Biol Rev 53: 81-122
    • (1978) Biol Rev , vol.53 , pp. 81-122
    • New, D.A.T.1
  • 16
    • 0000360265 scopus 로고
    • The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system
    • Kissane JM, Robins E (1958) The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system. J Biol Chem 233: 184-188
    • (1958) J Biol Chem , vol.233 , pp. 184-188
    • Kissane, J.M.1    Robins, E.2
  • 17
    • 0014978068 scopus 로고
    • An improved fluorometric assay for DNA
    • Hinegardner RT (1971) An improved fluorometric assay for DNA. Anal Biochem 39: 197-201
    • (1971) Anal Biochem , vol.39 , pp. 197-201
    • Hinegardner, R.T.1
  • 18
    • 0016227733 scopus 로고
    • Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum
    • Bondar RJL, Mead DC (1974) Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum. Clin Chem 20: 586-590
    • (1974) Clin Chem , vol.20 , pp. 586-590
    • Bondar, R.J.L.1    Mead, D.C.2
  • 19
    • 0022219133 scopus 로고
    • Use of protein-based standards in automated colorimetric determination of fructosamine in serum
    • Baker JR, Metcalf PA, Johnson RN, Newman D, Rietz P (1985) Use of protein-based standards in automated colorimetric determination of fructosamine in serum. Clin Chem 31: 1550-1554
    • (1985) Clin Chem , vol.31 , pp. 1550-1554
    • Baker, J.R.1    Metcalf, P.A.2    Johnson, R.N.3    Newman, D.4    Rietz, P.5
  • 22
    • 0018424273 scopus 로고
    • Manual and continuous-flow colorimetry of triacylglycerols by a fully enzymatic method
    • Megraw EM, Dunn DE, Biggs HG (1979) Manual and continuous-flow colorimetry of triacylglycerols by a fully enzymatic method. Clin Chem 25: 273-278
    • (1979) Clin Chem , vol.25 , pp. 273-278
    • Megraw, E.M.1    Dunn, D.E.2    Biggs, H.G.3
  • 23
    • 0020612736 scopus 로고
    • The storage stability of 3-hydroxybutyrate in serum, plasma and whole blood
    • Custer EM, Myers JL, Poffenbarger PL, Schoen I (1983) The storage stability of 3-hydroxybutyrate in serum, plasma and whole blood. Am J Clin Pathol 80: 375-380
    • (1983) Am J Clin Pathol , vol.80 , pp. 375-380
    • Custer, E.M.1    Myers, J.L.2    Poffenbarger, P.L.3    Schoen, I.4
  • 24
    • 0015109591 scopus 로고
    • Automated reaction-rate method for determination of serum creatinine with the CentrifiChem
    • Fabiny DL, Ertinghausen G (1971) Automated reaction-rate method for determination of serum creatinine with the CentrifiChem. Clin Chem 17: 696-700
    • (1971) Clin Chem , vol.17 , pp. 696-700
    • Fabiny, D.L.1    Ertinghausen, G.2
  • 25
    • 0016228243 scopus 로고
    • Editorial: Scandinavian standardizations of enzyme determination
    • Strömme J, Eldjarn L (1974) Editorial: Scandinavian standardizations of enzyme determination. Scand J Clin Lab Invest 33: 287-289
    • (1974) Scand J Clin Lab Invest , vol.33 , pp. 287-289
    • Strömme, J.1    Eldjarn, L.2
  • 26
    • 18344403490 scopus 로고
    • Temperature-conversion factors for four enzymes in commercial control sera
    • Hafkenscheid JC, Kohler BE (1986) Temperature-conversion factors for four enzymes in commercial control sera. Clin Chem 32: 1616
    • (1986) Clin Chem , vol.32 , pp. 1616
    • Hafkenscheid, J.C.1    Kohler, B.E.2
  • 27
    • 0015517956 scopus 로고
    • An improved method of plasma deproteination with sulphosalicylic acid for determining amino acids and related compounds
    • Mondino A, Bongiovanni G, Fumero S, Rossi L (1972) An improved method of plasma deproteination with sulphosalicylic acid for determining amino acids and related compounds. J Chromatogr 74: 255-263
    • (1972) J Chromatogr , vol.74 , pp. 255-263
    • Mondino, A.1    Bongiovanni, G.2    Fumero, S.3    Rossi, L.4
  • 30
    • 0018536679 scopus 로고
    • Nutrient requirements of rat embryos undergoing organogenesis in vitro
    • Cockroft DL (1979) Nutrient requirements of rat embryos undergoing organogenesis in vitro. J Reprod Fertil 57: 505-510
    • (1979) J Reprod Fertil , vol.57 , pp. 505-510
    • Cockroft, D.L.1
  • 31
    • 0024831481 scopus 로고
    • Effects of interrupted insulin treatment on fetal outcome of pregnant diabetic rats
    • Eriksson RSM, Thunberg L, Eriksson UJ (1989) Effects of interrupted insulin treatment on fetal outcome of pregnant diabetic rats. Diabetes 38: 764-772
    • (1989) Diabetes , vol.38 , pp. 764-772
    • Eriksson, R.S.M.1    Thunberg, L.2    Eriksson, U.J.3
  • 33
    • 2642615188 scopus 로고
    • Embryos transgenic for superoxide dismutase (SOD) show resistance to a teratogenic diabetic environment in vitro
    • Abstract
    • Eriksson UJ, Borg LAH, Sjöberg A, Wentzel P, Hagay Z, Groner Y (1993) Embryos transgenic for superoxide dismutase (SOD) show resistance to a teratogenic diabetic environment in vitro. Diabetologia 36[Suppl 1]:A41 (Abstract)
    • (1993) Diabetologia , vol.36 , Issue.1 SUPPL.
    • Eriksson, U.J.1    Borg, L.A.H.2    Sjöberg, A.3    Wentzel, P.4    Hagay, Z.5    Groner, Y.6
  • 34
    • 0028892376 scopus 로고
    • Prevention of hyperglycemia-associated embryopathy by embryonic overexpression of the free radical scavenger copper zinc superoxide dismutase gene
    • Hagay ZJ, Weiss Y, Zusman I, Peled-Kamar M, Eriksson UJ, Groner Y (1995) Prevention of hyperglycemia-associated embryopathy by embryonic overexpression of the free radical scavenger copper zinc superoxide dismutase gene. Am J Obstet Gynecol 173: 1036-1041
    • (1995) Am J Obstet Gynecol , vol.173 , pp. 1036-1041
    • Hagay, Z.J.1    Weiss, Y.2    Zusman, I.3    Peled-Kamar, M.4    Eriksson, U.J.5    Groner, Y.6
  • 35
    • 0029957231 scopus 로고    scopus 로고
    • Pregnant diabetic rats fed the antioxidant butylated hydroxytoluene show decreased occurrence of malformations in the offspring
    • Eriksson UJ, Simán CM (1996) Pregnant diabetic rats fed the antioxidant butylated hydroxytoluene show decreased occurrence of malformations in the offspring. Diabetes 45: 1497-1502
    • (1996) Diabetes , vol.45 , pp. 1497-1502
    • Eriksson, U.J.1    Simán, C.M.2
  • 36
    • 0343439058 scopus 로고
    • Vitamin e treatment blocks dysmorphogenesis in embryos of diabetic rats
    • Abstract
    • Simán CM, Borg LAH, Eriksson UJ (1995) Vitamin E treatment blocks dysmorphogenesis in embryos of diabetic rats. Diabetologia 38[Suppl 1]:A22 (Abstract)
    • (1995) Diabetologia , vol.38 , Issue.1 SUPPL.
    • Simán, C.M.1    Borg, L.A.H.2    Eriksson, U.J.3
  • 37
    • 0029817297 scopus 로고    scopus 로고
    • Teratogenic effects of diabetes mellitus in the rat. Protection by vitamin E
    • Viana M, Herrera E, Bonet B (1996) Teratogenic effects of diabetes mellitus in the rat. Protection by vitamin E. Diabetologia 39: 1041-1046
    • (1996) Diabetologia , vol.39 , pp. 1041-1046
    • Viana, M.1    Herrera, E.2    Bonet, B.3
  • 38
    • 0029896116 scopus 로고    scopus 로고
    • Altered levels of scavenging enzymes in embryos subjected to a diabetic environment
    • Forsberg H, Borg LAH, Cagliero E, Eriksson UJ (1996) Altered levels of scavenging enzymes in embryos subjected to a diabetic environment. Free Rad Res 24: 451-459
    • (1996) Free Rad Res , vol.24 , pp. 451-459
    • Forsberg, H.1    Borg, L.A.H.2    Cagliero, E.3    Eriksson, U.J.4
  • 39
    • 8044236732 scopus 로고    scopus 로고
    • Altered metabolism and superoxide generation in neural tissue of rat embryos exposed to high glucose
    • in press
    • Yang X, Borg LAH, Eriksson UJ (1996) Altered metabolism and superoxide generation in neural tissue of rat embryos exposed to high glucose. Am J Physiol, in press
    • (1996) Am J Physiol
    • Yang, X.1    Borg, L.A.H.2    Eriksson, U.J.3
  • 40
    • 8044230350 scopus 로고    scopus 로고
    • Glucose decreases the levels of free oxygen radicals in rat embryonic cells in vitro
    • Abstract
    • Forsberg H, Eriksson UJ, Welsh N (1996) Glucose decreases the levels of free oxygen radicals in rat embryonic cells in vitro. Diabetologia 39 [Suppl 1]: A209 (Abstract)
    • (1996) Diabetologia , vol.39 , Issue.1 SUPPL.
    • Forsberg, H.1    Eriksson, U.J.2    Welsh, N.3
  • 41
    • 0029150524 scopus 로고
    • Significance of glutathione depletion and oxidative stress in early embryogenesis in glucose-induced rat embryo culture
    • Trocino RA, Akazawa S, Ishibashi M et al. (1995) Significance of glutathione depletion and oxidative stress in early embryogenesis in glucose-induced rat embryo culture. Diabetes 44: 992-998
    • (1995) Diabetes , vol.44 , pp. 992-998
    • Trocino, R.A.1    Akazawa, S.2    Ishibashi, M.3
  • 42
    • 0029863939 scopus 로고    scopus 로고
    • High glucose concentration inhibits migration of rat cranial neural crest cells in vitro
    • Suzuki N, Svensson K, Eriksson UJ (1996) High glucose concentration inhibits migration of rat cranial neural crest cells in vitro. Diabetologia 39: 401-411
    • (1996) Diabetologia , vol.39 , pp. 401-411
    • Suzuki, N.1    Svensson, K.2    Eriksson, U.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.