Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans

Diabetologia

Volumn 54, Issue 9, 2011, Pages 2358-2367

  Aronis, K N ^a   Diakopoulos, K N ^a   Fiorenza, C G ^a   Chamberland, J P ^a   Mantzoros, C S ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Angiogenesis; Angiogenin; Angiopoietin 1; Humans; Leptin; MMP9

Indexed keywords

ANGIOGENIC FACTOR; ANGIOGENIN; ANGIOPOIETIN 1; CALCIUM; ENDOTHELIAL CELL GROWTH FACTOR; GELATINASE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; LEPTIN; METRELEPTIN; NEU DIFFERENTIATION FACTOR; NEUTROPHIL COLLAGENASE; PLACEBO; PLATELET DERIVED GROWTH FACTOR AA; SERINE PROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 4; UROKINASE; VASCULOTROPIN; VITAMIN D;

ADULT; ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; EFFECT SIZE; FEMALE; HOSPITAL PATIENT; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; LEAN BODY WEIGHT; MALE; NORMAL HUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEOMICS; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE;

ADOLESCENT; ADULT; ANGIOGENESIS INDUCING AGENTS; ANGIOPOIETIN-1; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL GROWTH FACTORS; FEMALE; HUMANS; INJECTIONS, SUBCUTANEOUS; LEPTIN; MALE; MATRIX METALLOPROTEINASE 8; MATRIX METALLOPROTEINASE 9; NEOVASCULARIZATION, PHYSIOLOGIC; PLATELET-DERIVED GROWTH FACTOR; RIBONUCLEASE, PANCREATIC; THINNESS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 80054701106     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2201-x     Document Type: Article

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