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Volumn 111, Issue 9, 2003, Pages 1409-1421

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; LEPTIN; PLACEBO; RECOMBINANT METHIONYL HUMAN LEPTIN; RECOMBINANT PROTEIN; SOMATOMEDIN C; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 0037651108     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200317490     Document Type: Article
Times cited : (564)

References (56)
  • 1
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang, Y., et al. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature. 372:425-432.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1
  • 2
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague, C.T., et al. 1997. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature. 387:903-908.
    • (1997) Nature , vol.387 , pp. 903-908
    • Montague, C.T.1
  • 3
    • 0032014836 scopus 로고    scopus 로고
    • A leptin missense mutation associated with hypogonadism and morbid obesity
    • Scrobel, A., Issad, T., Camoin, L., Ozata, M., and Strosberg, A.D. 1998. A leptin missense mutation associated with hypogonadism and morbid obesity. Nat. Genet. 18:213-215.
    • (1998) Nat. Genet. , vol.18 , pp. 213-215
    • Scrobel, A.1    Issad, T.2    Camoin, L.3    Ozata, M.4    Strosberg, A.D.5
  • 4
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
    • Ozata, M., Ozdemir, I.C., and Licinio, J. 1999. Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J. Clin. Endocrinol. Metab. 84:3686-3695.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 3686-3695
    • Ozata, M.1    Ozdemir, I.C.2    Licinio, J.3
  • 5
    • 0029066265 scopus 로고
    • Effects of the obese gene product on body weight regulation in ob/ob mice
    • Pelleymounter, M.A., et al. 1995. Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 269:540-543.
    • (1995) Science , vol.269 , pp. 540-543
    • Pelleymounter, M.A.1
  • 6
    • 0033575993 scopus 로고    scopus 로고
    • Effects of recombinant leptin therapy in a child with congenital leptin deficiency
    • Farooqi, I.S., et al. 1999. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N. Engl. J. Med. 341:879-884.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 879-884
    • Farooqi, I.S.1
  • 7
    • 0042221558 scopus 로고    scopus 로고
    • Ultradian oscillations of leptin secretion in humans
    • Sinha, M.K., et al. 1996. Ultradian oscillations of leptin secretion in humans. Biochem. Biophys. Res. Commun. 228:733-738.
    • (1996) Biochem. Biophys. Res. Commun. , vol.228 , pp. 733-738
    • Sinha, M.K.1
  • 8
    • 0029896530 scopus 로고    scopus 로고
    • Role of leptin in the neuroendocrine response to fasting
    • Ahima, R.S., et al. 1996. Role of leptin in the neuroendocrine response to fasting. Nature. 382:250-252.
    • (1996) Nature , vol.382 , pp. 250-252
    • Ahima, R.S.1
  • 9
    • 0032065645 scopus 로고    scopus 로고
    • Clinical review 94: What's in a name? In search of leptin's physiologic role
    • Flier, J.S. 1998. Clinical review 94: what's in a name? In search of leptin's physiologic role. J. Clin. Endocrinol. Metab. 83:1407-1413.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 1407-1413
    • Flier, J.S.1
  • 10
    • 0033586747 scopus 로고    scopus 로고
    • The role of leptin in human obesity and disease: A review of current evidence
    • Mantzoros, C.S. 1999. The role of leptin in human obesity and disease: a review of current evidence. Ann. Intern. Med. 130:871-881.
    • (1999) Ann. Intern. Med. , vol.130 , pp. 871-881
    • Mantzoros, C.S.1
  • 11
    • 0029844267 scopus 로고    scopus 로고
    • Effect of fasting on serum leptin in normal human subjects
    • Boden, G., Chen, X., Mozzoli, M., and Ryan, I. 1996. Effect of fasting on serum leptin in normal human subjects. J. Clin. Endocrinol. Metab. 81:3419-3423.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3419-3423
    • Boden, G.1    Chen, X.2    Mozzoli, M.3    Ryan, I.4
  • 12
    • 0031014348 scopus 로고    scopus 로고
    • Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels
    • Weigle, D.S., et al. 1997. Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels. J. Clin. Endocrinol. Metab. 82:561-565.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 561-565
    • Weigle, D.S.1
  • 13
    • 16944364768 scopus 로고    scopus 로고
    • Human leptin levels are pulsatile and inversely related to pituitary-adrenal function
    • Licinio, J., et al. 1997. Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nat. Med. 3:575-579.
    • (1997) Nat. Med. , vol.3 , pp. 575-579
    • Licinio, J.1
  • 15
    • 0027468352 scopus 로고
    • Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men
    • Veldhuis, J.D., et al. 1993. Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men. J. Clin. Endocrinol. Metab. 76:587-592.
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , pp. 587-592
    • Veldhuis, J.D.1
  • 16
    • 0018415335 scopus 로고
    • Effect of tri-iodothyronine replacement on the metabolic and pituitary responses to starvation
    • Gardner, D.F., Kaplan, M.M., Stanley C.A., and Utiger, R.D. 1979. Effect of tri-iodothyronine replacement on the metabolic and pituitary responses to starvation. N. Engl. J. Med. 300:579-584.
    • (1979) N. Engl. J. Med. , vol.300 , pp. 579-584
    • Gardner, D.F.1    Kaplan, M.M.2    Stanley, C.A.3    Utiger, R.D.4
  • 17
    • 0038426829 scopus 로고    scopus 로고
    • Starvation
    • K.L. Becker, editor. Lippincott, Williams, and Wilkins. Philadelphia, Pennsylvania, USA
    • MacDonald, R.S., and Smith, R.J. 2001. Starvation. In Principles and practice of endocrinology and metabolism. K.L. Becker, editor. Lippincott, Williams, and Wilkins. Philadelphia, Pennsylvania, USA. 1247-1251.
    • (2001) Principles and Practice of Endocrinology and Metabolism , pp. 1247-1251
    • MacDonald, R.S.1    Smith, R.J.2
  • 18
    • 0028127946 scopus 로고
    • Nutritional regulation of the insulin-like growth factors
    • Thissen, J.P., Ketelslegers, J.M., and Underwood, L.E. 1994. Nutritional regulation of the insulin-like growth factors. Endocr. Rev. 15:80-101.
    • (1994) Endocr. Rev. , vol.15 , pp. 80-101
    • Thissen, J.P.1    Ketelslegers, J.M.2    Underwood, L.E.3
  • 19
    • 0017185968 scopus 로고
    • Plasma and urinary dopamine: Studies during fasting and exercise and in tetraplegic man
    • Christensen, N.J., Mathias, C.J., and Frankel, H.L. 1976. Plasma and urinary dopamine: studies during fasting and exercise and in tetraplegic man. Eur. J. Clin. Invest. 6:403-409.
    • (1976) Eur. J. Clin. Invest. , vol.6 , pp. 403-409
    • Christensen, N.J.1    Mathias, C.J.2    Frankel, H.L.3
  • 20
    • 0023914112 scopus 로고
    • Acute effects of short-term fasting on blood pressure, circulating noradrenaline and efferent sympathetic nerve activity
    • Andersson, B., Wallin, G., Hedner, T., Ahlberg, A., and Andersson, O.K. 1988. Acute effects of short-term fasting on blood pressure, circulating noradrenaline and efferent sympathetic nerve activity. Acta Med. Scand. 223:485-490.
    • (1988) Acta Med. Scand. , vol.223 , pp. 485-490
    • Andersson, B.1    Wallin, G.2    Hedner, T.3    Ahlberg, A.4    Andersson, O.K.5
  • 22
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement, K., et al. 1998. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature. 392:398-401.
    • (1998) Nature , vol.392 , pp. 398-401
    • Clement, K.1
  • 23
    • 17844366295 scopus 로고    scopus 로고
    • Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: Evidence for possible partial TSH regulation by leptin in humans
    • Mantzoros, C.S., et al. 2001. Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans. J. Clin. Endocrinol. Metab. 86:3284-3291.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 3284-3291
    • Mantzoros, C.S.1
  • 24
    • 13144293061 scopus 로고    scopus 로고
    • Synchronicity, of frequency sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women
    • Licinio, J., et al. 1998. Synchronicity, of frequency sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women. Proc. Natl. Acad. Sci. U. S. A. 95:2541-2546.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 2541-2546
    • Licinio, J.1
  • 25
    • 0030943482 scopus 로고    scopus 로고
    • Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal-weight men
    • Aloi, J.A., Bergendahl, M., Iranmanesh, A., and Veldhuis, J.D. 1997. Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal-weight men. J. Clin. Endocrinol. Metab. 82:1543-1548.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 1543-1548
    • Aloi, J.A.1    Bergendahl, M.2    Iranmanesh, A.3    Veldhuis, J.D.4
  • 26
    • 0033008979 scopus 로고    scopus 로고
    • Serum leptin and gonadotropin levels in patients with anorexia nervosa during weight gain
    • Ballauff, A., et al. 1999. Serum leptin and gonadotropin levels in patients with anorexia nervosa during weight gain. Mol. Psychiatry. 4:71-75.
    • (1999) Mol. Psychiatry , vol.4 , pp. 71-75
    • Ballauff, A.1
  • 27
    • 0035695541 scopus 로고    scopus 로고
    • Leptin and the hypothalamic-pituitary regulation of the gonadotropin-gonadal axis
    • Chan, J.L., and Mantzoros, C.S. 2001. Leptin and the hypothalamic-pituitary regulation of the gonadotropin-gonadal axis. Pituitary 4:87-92.
    • (2001) Pituitary , vol.4 , pp. 87-92
    • Chan, J.L.1    Mantzoros, C.S.2
  • 29
    • 0030010388 scopus 로고    scopus 로고
    • Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
    • Chehab, F.F., Lim, M.E., and Lu, R. 1996. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat. Genet. 12:318-320.
    • (1996) Nat. Genet. , vol.12 , pp. 318-320
    • Chehab, F.F.1    Lim, M.E.2    Lu, R.3
  • 30
    • 0031051499 scopus 로고    scopus 로고
    • Leptin treatment rescues the sterility of genetically obese ob/ob males
    • Mounzih, K., Lu, R., and Chehab, F.F. 1997. Leptin treatment rescues the sterility of genetically obese ob/ob males. Endocrinology. 138:1190-1193.
    • (1997) Endocrinology , vol.138 , pp. 1190-1193
    • Mounzih, K.1    Lu, R.2    Chehab, F.F.3
  • 31
    • 0030980198 scopus 로고    scopus 로고
    • A longitudinal assessment of hormonal and physical alterations during normal puberty in boys: Rising leptin levels may signal the onset of puberty
    • Mantzoros, C.S., Flier, J.S., and Rogol, A.D. 1997. A longitudinal assessment of hormonal and physical alterations during normal puberty in boys: rising leptin levels may signal the onset of puberty. J. Clin. Endocrinol. Metab. 82:1066-1070.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 1066-1070
    • Mantzoros, C.S.1    Flier, J.S.2    Rogol, A.D.3
  • 32
    • 0032919990 scopus 로고    scopus 로고
    • Leptin's actions on the reproductive axis: Perspectives and mechanisms
    • Cunningham, M.J., Clifton, D.K., and Steiner, R.A. 1999. Leptin's actions on the reproductive axis: perspectives and mechanisms. Biol. Reprod 60:216-222.
    • (1999) Biol. Reprod. , vol.60 , pp. 216-222
    • Cunningham, M.J.1    Clifton, D.K.2    Steiner, R.A.3
  • 33
    • 0032917804 scopus 로고    scopus 로고
    • Physiological perspectives on leptin as a regulator of reproduction: Role in timing puberty
    • Foster, D.L., and Nagatani, S. 1999. Physiological perspectives on leptin as a regulator of reproduction: role in timing puberty. Biol. Reprod. 60:205-215.
    • (1999) Biol. Reprod. , vol.60 , pp. 205-215
    • Foster, D.L.1    Nagatani, S.2
  • 34
    • 0036800760 scopus 로고    scopus 로고
    • Beneficial effects of leptin on obesity, T cell hvporesponsiveness and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
    • doi:10.1172/JC1200215693
    • Farooqi, I.S., et al. 2002. Beneficial effects of leptin on obesity, T cell hvporesponsiveness and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J. Clin. Invest. 110:1093-1103. doi:10.1172/JC1200215693.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1093-1103
    • Farooqi, I.S.1
  • 35
    • 0033031803 scopus 로고    scopus 로고
    • Constitutional delay in growth and puberty (CDGP) is associated with hypoleptinaemia
    • Gill, M.S., Hall, C.M., Tillmann, V. and Clayton, P.E. 1999. Constitutional delay in growth and puberty (CDGP) is associated with hypoleptinaemia. Clin. Endocrinol. 60:721-726.
    • (1999) Clin. Endocrinol. , vol.60 , pp. 721-726
    • Gill, M.S.1    Hall, C.M.2    Tillmann, V.3    Clayton, P.E.4
  • 36
    • 0030921181 scopus 로고    scopus 로고
    • Leptin is inversely related to age at menarche in human females
    • Matkovic, V., et al. 1997. Leptin is inversely related to age at menarche in human females. J. Clin. Endocrinol. Metab. 82:3239-3245.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 3239-3245
    • Matkovic, V.1
  • 38
    • 0026029398 scopus 로고
    • Influence of fasting and refeeding on 3,3′,5′-triiodothyronine metabolism in man
    • Lopresti, J.S., Gray, D., and Nicoloff, J.T. 1991. Influence of fasting and refeeding on 3,3′,5′-triiodothyronine metabolism in man. J. Clin. Endcrinol. Metab. 72:130-136.
    • (1991) J. Clin. Endocrinol. Metab. , vol.72 , pp. 130-136
    • Lopresti, J.S.1    Gray, D.2    Nicoloff, J.T.3
  • 39
    • 0025314444 scopus 로고
    • Pulsatile secretion of thyrotropin during fasting: A decrease of thyrotropin pulse amplitude
    • Romjin, J.A., et al. 1990. Pulsatile secretion of thyrotropin during fasting: a decrease of thyrotropin pulse amplitude. J. Clin. Endocrinol. Metab. 70:1631-1636.
    • (1990) J. Clin. Endocrinol. Metab. , vol.70 , pp. 1631-1636
    • Romjin, J.A.1
  • 41
    • 0000659858 scopus 로고    scopus 로고
    • Leptin prevents fasting-induced suppression ofprothyrorropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
    • Legradi, G., Emerson, C.H., Ahima, R.S., Flier,J.S., and Lechan, R.M. 1997. Leptin prevents fasting-induced suppression ofprothyrorropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology 138:2569-2576.
    • (1997) Endocrinology , vol.138 , pp. 2569-2576
    • Legradi, G.1    Emerson, C.H.2    Ahima, R.S.3    Flier, J.S.4    Lechan, R.M.5
  • 42
    • 0036093071 scopus 로고    scopus 로고
    • Low dose leptin administration reverses effects of sustained weight reduction on energy expenditure and circulating concentrations of thyroid hormones
    • Rosenbaum, M., Murphy, E.M., Heymsfield, S.B., Matthews, D.E., and Leibel, R.L. 2002. Low dose leptin administration reverses effects of sustained weight reduction on energy expenditure and circulating concentrations of thyroid hormones. J. Clin. Endocrinol. Metab. 85:2391-2394.
    • (2002) J. Clin. Endocrinol. Metab. , vol.85 , pp. 2391-2394
    • Rosenbaum, M.1    Murphy, E.M.2    Heymsfield, S.B.3    Matthews, D.E.4    Leibel, R.L.5
  • 43
    • 0023949155 scopus 로고
    • Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man
    • Ho, K.Y., et al. 1988. Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. J. Clin. Invest. 81:968-975.
    • (1988) J. Clin. Invest. , vol.81 , pp. 968-975
    • Ho, K.Y.1
  • 44
    • 0026529796 scopus 로고
    • Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men
    • Hartman, M.L., et al. 1992. Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men. J. Clin. Endocrinol. Metab. 74:757-765.
    • (1992) J. Clin. Endocrinol. Metab. , vol.74 , pp. 757-765
    • Hartman, M.L.1
  • 45
    • 0020307531 scopus 로고
    • Insulin-like growth factors in the fed and fasted states
    • Merimee, T.J., Zapf, J., and Froesch, E.R. 1982. Insulin-like growth factors in the fed and fasted states. J. Clin. Endocrinol. Metab. 55:999-1002.
    • (1982) J. Clin. Endocrinol. Metab. , vol.55 , pp. 999-1002
    • Merimee, T.J.1    Zapf, J.2    Froesch, E.R.3
  • 46
    • 0031751425 scopus 로고    scopus 로고
    • Leptin alters the response of the growth hormone releasing factor-growth hormone-insulin-like growth factor-I axis to fasting
    • LaPaglia, N., Steiner, J., Kirsteins, L., Emanuele, M., and Emanuele, N. 1998. Leptin alters the response of the growth hormone releasing factor-growth hormone-insulin-like growth factor-I axis to fasting. J. Endocrinol. 159:79-83.
    • (1998) J. Endocrinol. , vol.159 , pp. 79-83
    • LaPaglia, N.1    Steiner, J.2    Kirsteins, L.3    Emanuele, M.4    Emanuele, N.5
  • 47
    • 0024335356 scopus 로고
    • Fasting alters pulsatile and rhythmic cortisol release in normal man
    • Vance, M.L., and Thorner, M.O. 1989. Fasting alters pulsatile and rhythmic cortisol release in normal man. J. Clin. Endocrinol. Metab. 68:1013-1018.
    • (1989) J. Clin. Endocrinol. Metab. , vol.68 , pp. 1013-1018
    • Vance, M.L.1    Thorner, M.O.2
  • 49
    • 0032440815 scopus 로고    scopus 로고
    • Renal effects of leptin in normotensive, hypertensive, and obese rats
    • Villarreal, D., Reams, G., Freeman, R.H., and Taraben, A. 1998. Renal effects of leptin in normotensive, hypertensive, and obese rats. Am. J. Physiol. 275:R2056-R2060.
    • (1998) Am. J. Physiol. , vol.275
    • Villarreal, D.1    Reams, G.2    Freeman, R.H.3    Taraben, A.4
  • 50
    • 0030771886 scopus 로고    scopus 로고
    • Human leptin has natriuretic activity in the rat
    • Jackson, E.K., and Li, P. 1997. Human leptin has natriuretic activity in the rat. Am. J. Physiol. 272:F333-F338.
    • (1997) Am. J. Physiol. , vol.272
    • Jackson, E.K.1    Li, P.2
  • 52
    • 0035431169 scopus 로고    scopus 로고
    • The effects of leptin administration in non-obese human subjects
    • Mackintosh, R.M., and Hirsch, J. 2001. The effects of leptin administration in non-obese human subjects. Obes. Res. 9:462-469.
    • (2001) Obes. Res. , vol.9 , pp. 462-469
    • Mackintosh, R.M.1    Hirsch, J.2
  • 53
    • 0013964986 scopus 로고
    • Hormone-fuel interrelationships during fasting
    • Cahill, G.F., et al. 1966. Hormone-fuel interrelationships during fasting. J. Clin. Invest. 45:1751-1769.
    • (1966) J. Clin. Invest. , vol.45 , pp. 1751-1769
    • Cahill, G.F.1
  • 54
    • 0034522997 scopus 로고    scopus 로고
    • Weekly subcutaneous pegylated recombinant native human leptin (PEG-OB) administration in obese men
    • Hukshorn, C.J., et al. 2000. Weekly subcutaneous pegylated recombinant native human leptin (PEG-OB) administration in obese men. J. Clin. Endocrinol. Metab. 85:4003-4009.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 4003-4009
    • Hukshorn, C.J.1
  • 55
    • 0037456304 scopus 로고    scopus 로고
    • STAT3 signalling is required for leptin regulation of energy balance but not reproduction
    • Bates, S.H., et al. 2003. STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature. 421:856-859.
    • (2003) Nature , vol.421 , pp. 856-859
    • Bates, S.H.1
  • 56
    • 0036893007 scopus 로고    scopus 로고
    • Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis
    • Fekete, C., et al. 2002. Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis. Endocrinology. 143:4513-4519.
    • (2002) Endocrinology , vol.143 , pp. 4513-4519
    • Fekete, C.1


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