Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin αvβ5: Implications for angiogenesis in human obesity

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 2, 2010, Pages 200-206

  Heida, Nana Maria ^a   Leifheit Nestler, Maren ^a   Schroeter, Marco R ^a   Müller, Jan Peter ^a   Cheng, I Fen ^a   Henkel, Sarah ^a   Limbourg, Anne ^b   Limbourg, Florian P ^b   Alves, Frauke ^a   Quigley, James P ^c   Ruggeri, Zaverio M ^c   Hasenfuss, Gerd ^a   Konstantinides, Stavros ^a,d   Schäfer, Katrin ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

Angiogenesis; Circulating angiogenic cells; Leptin; Obesity; PTP1B; Src kinase

Indexed keywords

ALPHAVBETA5 INTEGRIN; CYTOKINE RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; PHOSPHOLIPASE C GAMMA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE 1B;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL MIGRATION; CHICK EMBRYO; CHORIOALLANTOIS; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVATION; EX VIVO STUDY; HINDLIMB; HUMAN; HUMAN CELL; HYPERLEPTINEMIA; IN VITRO STUDY; IN VIVO STUDY; LIMB ISCHEMIA; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ANIMALS; ANTIGENS, CD31; ANTIGENS, CD34; ANTIGENS, CD45; CASE-CONTROL STUDIES; CELL ADHESION; CELL MOVEMENT; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HINDLIMB; HUMANS; ISCHEMIA; JANUS KINASE 2; LEPTIN; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, NUDE; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; OBESITY; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RECEPTORS, LEPTIN; RECEPTORS, VITRONECTIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; SRC-FAMILY KINASES; TRANSFECTION; UP-REGULATION; WEIGHT LOSS;

EID: 75149193488     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.192807     Document Type: Article

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