Gamma-irradiated influenza virus uniquely induces IFN-I mediated lymphocyte activation independent of the TLR7/MyD88 pathway

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Furuya, Yoichi ^a,e   Chan, Jennifer ^b   Wan, En Chi ^b   Koskinen, Aulikki ^a   Diener, Kerrilyn R ^c,d   Hayball, John D ^b,c,d   Regner, Matthias ^a   Müllbacher, Arno ^a   Alsharifi, Mohammed ^a,b  

^a Biology and Environment   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c HANSON INSTITUTE   (Australia)

^d UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^e ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CD69 ANTIGEN; CD86 ANTIGEN; FORMALDEHYDE; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; INTERFERON; INTERFERON RECEPTOR; INTERFERON RECEPTOR 1; INTERFERON RECEPTOR 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; SIALIDASE; TLR7 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GAMMA IRRADIATION; IMMUNE RESPONSE; IN VIVO STUDY; INFLUENZA A; INFLUENZA VIRUS A; IONIZING RADIATION; LYMPHOCYTE ACTIVATION; LYSIS; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; SEMLIKI FOREST ALPHAVIRUS; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DOG; FEMALE; GAMMA RADIATION; HAMSTER; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; LYMPHOCYTE; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; VIROLOGY; VIRUS ACTIVATION;

INFLUENZA A VIRUS; MUS; ORTHOMYXOVIRIDAE; RABBIT FIBROMA VIRUS; SEMLIKI FOREST VIRUS;

ANIMALS; CELL LINE; CRICETINAE; DOGS; FEMALE; GAMMA RAYS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INTERFERON TYPE I; LYMPHOCYTES; MEMBRANE GLYCOPROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; NEURAMINIDASE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; TOLL-LIKE RECEPTOR 7; VIRUS ACTIVATION;

EID: 80053596774     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025765     Document Type: Article

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