Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): A computational study

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Kong, Xiangqian ^a   Ouyang, Sisheng ^a   Liang, Zhongjie ^a   Lu, Junyan ^a   Chen, Liang ^a   Shen, Bairong ^b   Li, Donghai ^c   Zheng, Mingyue ^a   Li, Keqin Kathy ^d   Luo, Cheng ^a,b   Jiang, Hualiang ^a,e  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SOOCHOW UNIVERSITY   (China)

^c NANJING UNIVERSITY   (China)

^d SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COREPRESSOR PROTEIN; FLAVINE ADENINE NUCLEOTIDE; HISTONE; HISTONE DEMETHYLASE; HISTONE H3; LYSINE SPECIFIC DEMETHYLASE 1; QUERCETIN; TYROSINE; UNCLASSIFIED DRUG; WATER; KDM1A PROTEIN, HUMAN;

ARTICLE; CATALYSIS; DEMETHYLATION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBSTRATE; MATHEMATICAL COMPUTING; MOLECULAR CLONING; MOLECULAR MECHANICS; MOLECULAR MODEL; MOLECULAR PROBE; MUTAGENESIS; PROTEIN METHYLATION; PROTEIN MOTIF; QUANTUM MECHANICS; SIMULATION; SURFACE PROPERTY; BIOLOGY; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR DYNAMICS;

COMPUTATIONAL BIOLOGY; FLAVIN-ADENINE DINUCLEOTIDE; HISTONE DEMETHYLASES; HUMANS; MOLECULAR DYNAMICS SIMULATION;

EID: 80053578497     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025444     Document Type: Article

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