pH dependence of a mammalian polyamine oxidase: Insights into substrate specificity and the role of lysine 315

Biochemistry

Volumn 48, Issue 7, 2009, Pages 1508-1516

  Pozzi, Michelle Henderson ^a   Gawandi, Vijay ^a   Fitzpatrick, Paul F ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE RESIDUES; ACTIVE SITES; AMINE OXIDATIONS; MONOAMINE OXIDASE; MUTANT PROTEINS; PH DEPENDENCES; PH DEPENDENTS; POLYAMINE; POLYAMINE OXIDASE; POSITIVELY CHARGED; PROTONATION STATE; SPERMIDINE; SUBSTRATE OXIDATIONS; SUBSTRATE SPECIFICITIES;

AMINES; AMINO ACIDS; MAMMALS; NITROGEN; ORGANIC COMPOUNDS; OXIDATION; RATE CONSTANTS; SUBSTRATES;

PH EFFECTS;

AMINE; AMINE OXIDASE (FLAVIN CONTAINING); LYSINE; METHIONINE; N1 ACETYLSPERMIDINE; NITROGEN; POLYAMINE OXIDASE; PUTRESCINE; QUERCETIN; SPERMIDINE; SPERMINE; OXIDOREDUCTASE;

ARTICLE; CATALYSIS; ENZYME METABOLISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; KINETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION REACTION;

ANIMALS; HYDROGEN-ION CONCENTRATION; KINETICS; LYSINE; MICE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 61749094173     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802227m     Document Type: Article

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