Insights into the mechanism of flavoprotein-catalyzed amine oxidation from nitrogen isotope effects on the reaction of N-methyltryptophan oxidase

Biochemistry

Volumn 46, Issue 25, 2007, Pages 7655-7664

  Ralph, Erik C ^a   Hirschi, Jennifer S ^a   Anderson, Mark A ^b   Cleland, W Wallace ^b   Singleton, Daniel A ^a   Fitzpatrick, Paul F ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISCRETE ELECTRON TRANSFER MECHANISMS; ENERGETICS; N-METHYLTRYPTOPHAN OXIDASE; SARCOSINE OXIDATION;

CATALYSIS; DENSITY FUNCTIONAL THEORY; ELECTRON TRANSITIONS; NITROGEN; OXIDATION; PH EFFECTS; PROTEINS; REACTION KINETICS;

AMINES;

AMINE; AMINE OXIDASE (FLAVIN CONTAINING); BACTERIAL ENZYME; FLAVOPROTEIN; HYDROGEN; ISOTOPE; N METHYLTRYPTOPHAN; N METHYLTRYPTOPHAN OXIDASE; NITROGEN; NITROGEN 15; OXIDOREDUCTASE; SARCOSINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DENSITY FUNCTIONAL THEORY; ELECTRON TRANSPORT; ENERGY TRANSFER; ENZYME MECHANISM; ESCHERICHIA COLI; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTON TRANSPORT;

AMINES; CATALYSIS; ESCHERICHIA COLI; FLAVIN-ADENINE DINUCLEOTIDE; KINETICS; NITROGEN ISOTOPES; OXIDATION-REDUCTION; OXIDOREDUCTASES, N-DEMETHYLATING;

ESCHERICHIA COLI;

EID: 34250852848     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700482h     Document Type: Article

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