-
3
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Bueler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, et al. (1993) Mice devoid of PrP are resistant to scrapie. Cell 73: 1339-1347.
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Bueler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.A.4
Autenried, P.5
-
4
-
-
0028349264
-
PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie
-
Goldmann W, Hunter N, Smith G, Foster J, Hope J, (1994) PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie. J Gen Virol 75 (Pt 5): 989-995.
-
(1994)
J Gen Virol
, vol.75
, Issue.Pt 5
, pp. 989-995
-
-
Goldmann, W.1
Hunter, N.2
Smith, G.3
Foster, J.4
Hope, J.5
-
5
-
-
0030856447
-
PrP genetics in sheep and the applications for scrapie and BSE
-
Hunter N, (1997) PrP genetics in sheep and the applications for scrapie and BSE. Trends Microbiol 5: 331-334.
-
(1997)
Trends Microbiol
, vol.5
, pp. 331-334
-
-
Hunter, N.1
-
6
-
-
0027478355
-
PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis
-
Laplanche JL, Chatelain J, Westaway D, Thomas S, Dussaucy M, et al. (1993) PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis. Genomics 15: 30-37.
-
(1993)
Genomics
, vol.15
, pp. 30-37
-
-
Laplanche, J.L.1
Chatelain, J.2
Westaway, D.3
Thomas, S.4
Dussaucy, M.5
-
7
-
-
50049104145
-
Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology
-
Benestad SL, Arsac JN, Goldmann W, Noremark M, (2008) Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology. Vet Res 39: 19.
-
(2008)
Vet Res
, vol.39
, pp. 19
-
-
Benestad, S.L.1
Arsac, J.N.2
Goldmann, W.3
Noremark, M.4
-
8
-
-
0042921669
-
Cases of scrapie with unusual features in Norway and designation of a new type, Nor98
-
Benestad SL, Sarradin P, Thu B, Schonheit J, Tranulis MA, et al. (2003) Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec 153: 202-208.
-
(2003)
Vet Rec
, vol.153
, pp. 202-208
-
-
Benestad, S.L.1
Sarradin, P.2
Thu, B.3
Schonheit, J.4
Tranulis, M.A.5
-
9
-
-
0022530549
-
Linkage of prion protein and scrapie incubation time genes
-
Carlson GA, Kingsbury DT, Goodman PA, Coleman S, Marshall ST, et al. (1986) Linkage of prion protein and scrapie incubation time genes. Cell 46: 503-511.
-
(1986)
Cell
, vol.46
, pp. 503-511
-
-
Carlson, G.A.1
Kingsbury, D.T.2
Goodman, P.A.3
Coleman, S.4
Marshall, S.T.5
-
10
-
-
0023467393
-
Distinct prion proteins in short and long scrapie incubation period mice
-
Westaway D, Goodman PA, Mirenda CA, McKinley MP, Carlson GA, et al. (1987) Distinct prion proteins in short and long scrapie incubation period mice. Cell 51: 651-662.
-
(1987)
Cell
, vol.51
, pp. 651-662
-
-
Westaway, D.1
Goodman, P.A.2
Mirenda, C.A.3
McKinley, M.P.4
Carlson, G.A.5
-
11
-
-
0031942579
-
Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent
-
Moore RC, Hope J, McBride PA, McConnell I, Selfridge J, et al. (1998) Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent. Nat Genet 18: 118-125.
-
(1998)
Nat Genet
, vol.18
, pp. 118-125
-
-
Moore, R.C.1
Hope, J.2
McBride, P.A.3
McConnell, I.4
Selfridge, J.5
-
12
-
-
0026099887
-
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis
-
Bruce ME, McConnell I, Fraser H, Dickinson AG, (1991) The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J Gen Virol 72 (Pt 3): 595-603.
-
(1991)
J Gen Virol
, vol.72
, Issue.Pt 3
, pp. 595-603
-
-
Bruce, M.E.1
McConnell, I.2
Fraser, H.3
Dickinson, A.G.4
-
13
-
-
0014500760
-
A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
-
Dickinson AG, Meikle VM, (1969) A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7. Genet Res 13: 213-225.
-
(1969)
Genet Res
, vol.13
, pp. 213-225
-
-
Dickinson, A.G.1
Meikle, V.M.2
-
14
-
-
0026496257
-
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism
-
Goldfarb LG, Petersen RB, Tabaton M, Brown P, LeBlanc AC, et al. (1992) Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism. Science 258: 806-808.
-
(1992)
Science
, vol.258
, pp. 806-808
-
-
Goldfarb, L.G.1
Petersen, R.B.2
Tabaton, M.3
Brown, P.4
LeBlanc, A.C.5
-
15
-
-
33645147707
-
Prion disease genetics
-
Mead S, (2006) Prion disease genetics. Eur J Hum Genet 14: 273-281.
-
(2006)
Eur J Hum Genet
, vol.14
, pp. 273-281
-
-
Mead, S.1
-
16
-
-
77955344991
-
Defining sporadic Creutzfeldt-Jakob disease strains and their transmission properties
-
Bishop MT, Will RG, Manson JC, (2010) Defining sporadic Creutzfeldt-Jakob disease strains and their transmission properties. Proc Natl Acad Sci U S A 107: 12005-12010.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12005-12010
-
-
Bishop, M.T.1
Will, R.G.2
Manson, J.C.3
-
17
-
-
2542618458
-
Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002
-
Head MW, Bunn TJ, Bishop MT, McLoughlin V, Lowrie S, et al. (2004) Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002. Ann Neurol 55: 851-859.
-
(2004)
Ann Neurol
, vol.55
, pp. 851-859
-
-
Head, M.W.1
Bunn, T.J.2
Bishop, M.T.3
McLoughlin, V.4
Lowrie, S.5
-
18
-
-
0035863452
-
Increased susceptibility to Kuru of carriers of the PRNP 129 methionine/methionine genotype
-
Lee HS, Brown P, Cervenakova L, Garruto RM, Alpers MP, et al. (2001) Increased susceptibility to Kuru of carriers of the PRNP 129 methionine/methionine genotype. J Infect Dis 183: 192-196.
-
(2001)
J Infect Dis
, vol.183
, pp. 192-196
-
-
Lee, H.S.1
Brown, P.2
Cervenakova, L.3
Garruto, R.M.4
Alpers, M.P.5
-
19
-
-
10044224475
-
Human prion protein with valine 129 prevents expression of variant CJD phenotype
-
Wadsworth JD, Asante EA, Desbruslais M, Linehan JM, Joiner S, et al. (2004) Human prion protein with valine 129 prevents expression of variant CJD phenotype. Science 306: 1793-1796.
-
(2004)
Science
, vol.306
, pp. 1793-1796
-
-
Wadsworth, J.D.1
Asante, E.A.2
Desbruslais, M.3
Linehan, J.M.4
Joiner, S.5
-
20
-
-
0025820942
-
Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease
-
Palmer MS, Dryden AJ, Hughes JT, Collinge J, (1991) Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease. Nature 352: 340-342.
-
(1991)
Nature
, vol.352
, pp. 340-342
-
-
Palmer, M.S.1
Dryden, A.J.2
Hughes, J.T.3
Collinge, J.4
-
21
-
-
0031842845
-
Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease
-
Shibuya S, Higuchi J, Shin RW, Tateishi J, Kitamoto T, (1998) Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease. Ann Neurol 43: 826-828.
-
(1998)
Ann Neurol
, vol.43
, pp. 826-828
-
-
Shibuya, S.1
Higuchi, J.2
Shin, R.W.3
Tateishi, J.4
Kitamoto, T.5
-
22
-
-
63649142297
-
Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection
-
Hizume M, Kobayashi A, Teruya K, Ohashi H, Ironside JW, et al. (2009) Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection. J Biol Chem 284: 3603-3609.
-
(2009)
J Biol Chem
, vol.284
, pp. 3603-3609
-
-
Hizume, M.1
Kobayashi, A.2
Teruya, K.3
Ohashi, H.4
Ironside, J.W.5
-
23
-
-
77955435336
-
Heterozygosity at polymorphic codon 219 in variant creutzfeldt-jakob disease
-
Lukic A, Beck J, Joiner S, Fearnley J, Sturman S, et al. (2010) Heterozygosity at polymorphic codon 219 in variant creutzfeldt-jakob disease. Arch Neurol 67: 1021-1023.
-
(2010)
Arch Neurol
, vol.67
, pp. 1021-1023
-
-
Lukic, A.1
Beck, J.2
Joiner, S.3
Fearnley, J.4
Sturman, S.5
-
24
-
-
70949091205
-
A novel protective prion protein variant that colocalizes with kuru exposure
-
Mead S, Whitfield J, Poulter M, Shah P, Uphill J, et al. (2009) A novel protective prion protein variant that colocalizes with kuru exposure. N Engl J Med 361: 2056-2065.
-
(2009)
N Engl J Med
, vol.361
, pp. 2056-2065
-
-
Mead, S.1
Whitfield, J.2
Poulter, M.3
Shah, P.4
Uphill, J.5
-
25
-
-
0242684410
-
Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics
-
Mead S, Stumpf MP, Whitfield J, Beck JA, Poulter M, et al. (2003) Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics. Science 300: 640-643.
-
(2003)
Science
, vol.300
, pp. 640-643
-
-
Mead, S.1
Stumpf, M.P.2
Whitfield, J.3
Beck, J.A.4
Poulter, M.5
-
26
-
-
77954102231
-
PRNP allelic series from 19 years of prion protein gene sequencing at the MRC Prion Unit
-
Beck JA, Poulter M, Campbell TA, Adamson G, Uphill JB, et al. (2010) PRNP allelic series from 19 years of prion protein gene sequencing at the MRC Prion Unit. Hum Mutat 31: E1551-1563.
-
(2010)
Hum Mutat
, vol.31
-
-
Beck, J.A.1
Poulter, M.2
Campbell, T.A.3
Adamson, G.4
Uphill, J.B.5
-
27
-
-
68849129618
-
A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP
-
Yang W, Cook J, Rassbach B, Lemus A, DeArmond SJ, et al. (2009) A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP. J Neurosci 29: 10072-10080.
-
(2009)
J Neurosci
, vol.29
, pp. 10072-10080
-
-
Yang, W.1
Cook, J.2
Rassbach, B.3
Lemus, A.4
DeArmond, S.J.5
-
28
-
-
0025681138
-
Spontaneous neurodegeneration in transgenic mice with mutant prion protein
-
Hsiao KK, Scott M, Foster D, Groth DF, DeArmond SJ, et al. (1990) Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science 250: 1587-1590.
-
(1990)
Science
, vol.250
, pp. 1587-1590
-
-
Hsiao, K.K.1
Scott, M.2
Foster, D.3
Groth, D.F.4
DeArmond, S.J.5
-
29
-
-
22744448690
-
Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice
-
Nazor KE, Kuhn F, Seward T, Green M, Zwald D, et al. (2005) Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice. Embo J 24: 2472-2480.
-
(2005)
Embo J
, vol.24
, pp. 2472-2480
-
-
Nazor, K.E.1
Kuhn, F.2
Seward, T.3
Green, M.4
Zwald, D.5
-
30
-
-
0242351736
-
Transmission of murine scrapie to P101L transgenic mice
-
Barron RM, Thomson V, King D, Shaw J, Melton DW, et al. (2003) Transmission of murine scrapie to P101L transgenic mice. J Gen Virol 84: 3165-3172.
-
(2003)
J Gen Virol
, vol.84
, pp. 3165-3172
-
-
Barron, R.M.1
Thomson, V.2
King, D.3
Shaw, J.4
Melton, D.W.5
-
31
-
-
0035903461
-
Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers
-
Barron RM, Thomson V, Jamieson E, Melton DW, Ironside J, et al. (2001) Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers. Embo J 20: 5070-5078.
-
(2001)
Embo J
, vol.20
, pp. 5070-5078
-
-
Barron, R.M.1
Thomson, V.2
Jamieson, E.3
Melton, D.W.4
Ironside, J.5
-
32
-
-
0033485260
-
A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy
-
Manson JC, Jamieson E, Baybutt H, Tuzi NL, Barron R, et al. (1999) A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy. Embo J 18: 6855-6864.
-
(1999)
Embo J
, vol.18
, pp. 6855-6864
-
-
Manson, J.C.1
Jamieson, E.2
Baybutt, H.3
Tuzi, N.L.4
Barron, R.5
-
33
-
-
68949163542
-
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
-
Jackson WS, Borkowski AW, Faas H, Steele AD, King OD, et al. (2009) Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice. Neuron 63: 438-450.
-
(2009)
Neuron
, vol.63
, pp. 438-450
-
-
Jackson, W.S.1
Borkowski, A.W.2
Faas, H.3
Steele, A.D.4
King, O.D.5
-
34
-
-
0035956518
-
Inherited prion disease caused by the V210I mutation: transmission to transgenic mice
-
Mastrianni JA, Capellari S, Telling GC, Han D, Bosque P, et al. (2001) Inherited prion disease caused by the V210I mutation: transmission to transgenic mice. Neurology 57: 2198-2205.
-
(2001)
Neurology
, vol.57
, pp. 2198-2205
-
-
Mastrianni, J.A.1
Capellari, S.2
Telling, G.C.3
Han, D.4
Bosque, P.5
-
35
-
-
56349096340
-
Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model
-
Dossena S, Imeri L, Mangieri M, Garofoli A, Ferrari L, et al. (2008) Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model. Neuron 60: 598-609.
-
(2008)
Neuron
, vol.60
, pp. 598-609
-
-
Dossena, S.1
Imeri, L.2
Mangieri, M.3
Garofoli, A.4
Ferrari, L.5
-
36
-
-
0032427904
-
Neurological illness in transgenic mice expressing a prion protein with an insertional mutation
-
Chiesa R, Piccardo P, Ghetti B, Harris DA, (1998) Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. Neuron 21: 1339-1351.
-
(1998)
Neuron
, vol.21
, pp. 1339-1351
-
-
Chiesa, R.1
Piccardo, P.2
Ghetti, B.3
Harris, D.A.4
-
37
-
-
58549102983
-
De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis
-
Sigurdson CJ, Nilsson KP, Hornemann S, Heikenwalder M, Manco G, et al. (2009) De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis. Proc Natl Acad Sci U S A 106: 304-309.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 304-309
-
-
Sigurdson, C.J.1
Nilsson, K.P.2
Hornemann, S.3
Heikenwalder, M.4
Manco, G.5
-
38
-
-
77954972690
-
A molecular switch controls interspecies prion disease transmission in mice
-
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Fernandez-Borges N, et al. (2010) A molecular switch controls interspecies prion disease transmission in mice. J Clin Invest 120: 2590-2599.
-
(2010)
J Clin Invest
, vol.120
, pp. 2590-2599
-
-
Sigurdson, C.J.1
Nilsson, K.P.2
Hornemann, S.3
Manco, G.4
Fernandez-Borges, N.5
-
39
-
-
20344394154
-
Anchorless prion protein results in infectious amyloid disease without clinical scrapie
-
Chesebro B, Trifilo M, Race R, Meade-White K, Teng C, et al. (2005) Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science 308: 1435-1439.
-
(2005)
Science
, vol.308
, pp. 1435-1439
-
-
Chesebro, B.1
Trifilo, M.2
Race, R.3
Meade-White, K.4
Teng, C.5
-
40
-
-
34247589069
-
Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion protein
-
Meade-White K, Race B, Trifilo M, Bossers A, Favara C, et al. (2007) Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion protein. J Virol 81: 4533-4539.
-
(2007)
J Virol
, vol.81
, pp. 4533-4539
-
-
Meade-White, K.1
Race, B.2
Trifilo, M.3
Bossers, A.4
Favara, C.5
-
41
-
-
0029863648
-
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
Fischer M, Rulicke T, Raeber A, Sailer A, Moser M, et al. (1996) Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. Embo J 15: 1255-1264.
-
(1996)
Embo J
, vol.15
, pp. 1255-1264
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
Sailer, A.4
Moser, M.5
-
42
-
-
0028420937
-
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
-
Manson JC, Clarke AR, Hooper ML, Aitchison L, McConnell I, et al. (1994) 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol 8: 121-127.
-
(1994)
Mol Neurobiol
, vol.8
, pp. 121-127
-
-
Manson, J.C.1
Clarke, A.R.2
Hooper, M.L.3
Aitchison, L.4
McConnell, I.5
-
43
-
-
0001552281
-
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
-
Shmerling D, Hegyi I, Fischer M, Blattler T, Brandner S, et al. (1998) Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 93: 203-214.
-
(1998)
Cell
, vol.93
, pp. 203-214
-
-
Shmerling, D.1
Hegyi, I.2
Fischer, M.3
Blattler, T.4
Brandner, S.5
-
44
-
-
0035427232
-
Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH
-
Matsunaga Y, Peretz D, Williamson A, Burton D, Mehlhorn I, et al. (2001) Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH. Proteins 44: 110-118.
-
(2001)
Proteins
, vol.44
, pp. 110-118
-
-
Matsunaga, Y.1
Peretz, D.2
Williamson, A.3
Burton, D.4
Mehlhorn, I.5
-
45
-
-
56349149507
-
In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification
-
Meyerett C, Michel B, Pulford B, Spraker TR, Nichols TA, et al. (2008) In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification. Virology 382: 267-276.
-
(2008)
Virology
, vol.382
, pp. 267-276
-
-
Meyerett, C.1
Michel, B.2
Pulford, B.3
Spraker, T.R.4
Nichols, T.A.5
-
46
-
-
0028052363
-
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
-
Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, et al. (1994) Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell 76: 117-129.
-
(1994)
Cell
, vol.76
, pp. 117-129
-
-
Westaway, D.1
DeArmond, S.J.2
Cayetano-Canlas, J.3
Groth, D.4
Foster, D.5
-
47
-
-
22844434827
-
Cyclic amplification of protein misfolding and aggregation
-
Saa P, Castilla J, Soto C, (2005) Cyclic amplification of protein misfolding and aggregation. Methods Mol Biol 299: 53-65.
-
(2005)
Methods Mol Biol
, vol.299
, pp. 53-65
-
-
Saa, P.1
Castilla, J.2
Soto, C.3
-
48
-
-
0036791019
-
Dominant-negative inhibition of prion replication in transgenic mice
-
Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, et al. (2002) Dominant-negative inhibition of prion replication in transgenic mice. Proc Natl Acad Sci U S A 99: 13079-13084.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13079-13084
-
-
Perrier, V.1
Kaneko, K.2
Safar, J.3
Vergara, J.4
Tremblay, P.5
-
49
-
-
0028364192
-
Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells
-
Priola SA, Caughey B, Race RE, Chesebro B, (1994) Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells. J Virol 68: 4873-4878.
-
(1994)
J Virol
, vol.68
, pp. 4873-4878
-
-
Priola, S.A.1
Caughey, B.2
Race, R.E.3
Chesebro, B.4
-
50
-
-
0011869065
-
Further observations on the experimental transmission of scrapie from sheep and goats to laboratory mice
-
Zlotnik I, Rennie JC, (1963) Further observations on the experimental transmission of scrapie from sheep and goats to laboratory mice. J Comp Pathol 73: 150-162.
-
(1963)
J Comp Pathol
, vol.73
, pp. 150-162
-
-
Zlotnik, I.1
Rennie, J.C.2
-
51
-
-
0024325787
-
The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice
-
Kimberlin RH, Walker CA, Fraser H, (1989) The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice. J Gen Virol 70 (Pt 8): 2017-2025.
-
(1989)
J Gen Virol
, vol.70
, Issue.Pt 8
, pp. 2017-2025
-
-
Kimberlin, R.H.1
Walker, C.A.2
Fraser, H.3
-
52
-
-
0017866857
-
Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture
-
Kimberlin RH, Walker CA, (1978) Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture. J Gen Virol 39: 487-496.
-
(1978)
J Gen Virol
, vol.39
, pp. 487-496
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
53
-
-
67650747654
-
Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions
-
Caughey B, Baron GS, Chesebro B, Jeffrey M, (2009) Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions. Annu Rev Biochem 78: 177-204.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 177-204
-
-
Caughey, B.1
Baron, G.S.2
Chesebro, B.3
Jeffrey, M.4
-
54
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge J, Clarke AR, (2007) A general model of prion strains and their pathogenicity. Science 318: 930-936.
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
55
-
-
78349273618
-
Review: contribution of transgenic models to understanding human prion disease
-
Wadsworth JD, Asante EA, Collinge J, (2010) Review: contribution of transgenic models to understanding human prion disease. Neuropathol Appl Neurobiol 36: 576-597.
-
(2010)
Neuropathol Appl Neurobiol
, vol.36
, pp. 576-597
-
-
Wadsworth, J.D.1
Asante, E.A.2
Collinge, J.3
-
56
-
-
1642633056
-
Conformational variations in an infectious protein determine prion strain differences
-
Tanaka M, Chien P, Naber N, Cooke R, Weissman JS, (2004) Conformational variations in an infectious protein determine prion strain differences. Nature 428: 323-328.
-
(2004)
Nature
, vol.428
, pp. 323-328
-
-
Tanaka, M.1
Chien, P.2
Naber, N.3
Cooke, R.4
Weissman, J.S.5
-
57
-
-
17044435107
-
Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins
-
Tanaka M, Chien P, Yonekura K, Weissman JS, (2005) Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. Cell 121: 49-62.
-
(2005)
Cell
, vol.121
, pp. 49-62
-
-
Tanaka, M.1
Chien, P.2
Yonekura, K.3
Weissman, J.S.4
-
58
-
-
33746698975
-
The physical basis of how prion conformations determine strain phenotypes
-
Tanaka M, Collins SR, Toyama BH, Weissman JS, (2006) The physical basis of how prion conformations determine strain phenotypes. Nature 442: 585-589.
-
(2006)
Nature
, vol.442
, pp. 585-589
-
-
Tanaka, M.1
Collins, S.R.2
Toyama, B.H.3
Weissman, J.S.4
-
59
-
-
0032560124
-
Scrapie infectivity found in resistant species
-
Race R, Chesebro B, (1998) Scrapie infectivity found in resistant species. Nature 392: 770.
-
(1998)
Nature
, vol.392
, pp. 770
-
-
Race, R.1
Chesebro, B.2
-
60
-
-
0036891092
-
Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages
-
Race R, Meade-White K, Raines A, Raymond GJ, Caughey B, et al. (2002) Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages. J Infect Dis 186 (Suppl 2): S166-170.
-
(2002)
J Infect Dis
, vol.186
, Issue.SUPPL. 2
-
-
Race, R.1
Meade-White, K.2
Raines, A.3
Raymond, G.J.4
Caughey, B.5
-
61
-
-
0034790796
-
Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans
-
Race R, Raines A, Raymond GJ, Caughey B, Chesebro B, (2001) Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans. J Virol 75: 10106-10112.
-
(2001)
J Virol
, vol.75
, pp. 10106-10112
-
-
Race, R.1
Raines, A.2
Raymond, G.J.3
Caughey, B.4
Chesebro, B.5
-
62
-
-
0036246734
-
New Zealand sheep with scrapie-susceptible PrP genotypes succumb to experimental challenge with a sheep-passaged scrapie isolate (SSBP/1)
-
Houston EF, Halliday SI, Jeffrey M, Goldmann W, Hunter N, (2002) New Zealand sheep with scrapie-susceptible PrP genotypes succumb to experimental challenge with a sheep-passaged scrapie isolate (SSBP/1). J Gen Virol 83: 1247-1250.
-
(2002)
J Gen Virol
, vol.83
, pp. 1247-1250
-
-
Houston, E.F.1
Halliday, S.I.2
Jeffrey, M.3
Goldmann, W.4
Hunter, N.5
-
63
-
-
30844454873
-
Ovine infection with the agents of scrapie (CH1641 isolate) and bovine spongiform encephalopathy: immunochemical similarities can be resolved by immunohistochemistry
-
Jeffrey M, Gonzalez L, Chong A, Foster J, Goldmann W, et al. (2006) Ovine infection with the agents of scrapie (CH1641 isolate) and bovine spongiform encephalopathy: immunochemical similarities can be resolved by immunohistochemistry. J Comp Pathol 134: 17-29.
-
(2006)
J Comp Pathol
, vol.134
, pp. 17-29
-
-
Jeffrey, M.1
Gonzalez, L.2
Chong, A.3
Foster, J.4
Goldmann, W.5
-
64
-
-
58149380989
-
In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie
-
Thorne L, Terry LA, (2008) In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie. J Gen Virol 89: 3177-3184.
-
(2008)
J Gen Virol
, vol.89
, pp. 3177-3184
-
-
Thorne, L.1
Terry, L.A.2
-
65
-
-
50249157526
-
Crossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions
-
Castilla J, Gonzalez-Romero D, Saa P, Morales R, De Castro J, et al. (2008) Crossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions. Cell 134: 757-768.
-
(2008)
Cell
, vol.134
, pp. 757-768
-
-
Castilla, J.1
Gonzalez-Romero, D.2
Saa, P.3
Morales, R.4
De Castro, J.5
-
66
-
-
70149110670
-
The unfolding of the prion protein sheds light on the mechanisms of prion susceptibility and species barrier
-
Robinson PJ, Pinheiro TJ, (2009) The unfolding of the prion protein sheds light on the mechanisms of prion susceptibility and species barrier. Biochemistry 48: 8551-8558.
-
(2009)
Biochemistry
, vol.48
, pp. 8551-8558
-
-
Robinson, P.J.1
Pinheiro, T.J.2
-
67
-
-
35248848952
-
Ser170 controls the conformational multiplicity of the loop 166-175 in prion proteins: implication for conversion and species barrier
-
Gorfe AA, Caflisch A, (2007) Ser170 controls the conformational multiplicity of the loop 166-175 in prion proteins: implication for conversion and species barrier. Faseb J 21: 3279-3287.
-
(2007)
Faseb J
, vol.21
, pp. 3279-3287
-
-
Gorfe, A.A.1
Caflisch, A.2
-
68
-
-
52949137870
-
NMR structure of the bank vole prion protein at 20 degrees C contains a structured loop of residues 165-171
-
Christen B, Perez DR, Hornemann S, Wuthrich K, (2008) NMR structure of the bank vole prion protein at 20 degrees C contains a structured loop of residues 165-171. J Mol Biol 383: 306-312.
-
(2008)
J Mol Biol
, vol.383
, pp. 306-312
-
-
Christen, B.1
Perez, D.R.2
Hornemann, S.3
Wuthrich, K.4
-
69
-
-
0028822204
-
A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells
-
Priola SA, Chesebro B, (1995) A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. J Virol 69: 7754-7758.
-
(1995)
J Virol
, vol.69
, pp. 7754-7758
-
-
Priola, S.A.1
Chesebro, B.2
-
70
-
-
0030931519
-
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
-
Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, et al. (1997) Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proc Natl Acad Sci U S A 94: 10069-10074.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10069-10074
-
-
Kaneko, K.1
Zulianello, L.2
Scott, M.3
Cooper, C.M.4
Wallace, A.C.5
-
71
-
-
0035041973
-
Efficient conversion of normal prion protein (PrP) by abnormal hamster PrP is determined by homology at amino acid residue 155
-
Priola SA, Chabry J, Chan K, (2001) Efficient conversion of normal prion protein (PrP) by abnormal hamster PrP is determined by homology at amino acid residue 155. J Virol 75: 4673-4680.
-
(2001)
J Virol
, vol.75
, pp. 4673-4680
-
-
Priola, S.A.1
Chabry, J.2
Chan, K.3
-
72
-
-
0037301367
-
Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform
-
Vorberg I, Groschup MH, Pfaff E, Priola SA, (2003) Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform. J Virol 77: 2003-2009.
-
(2003)
J Virol
, vol.77
, pp. 2003-2009
-
-
Vorberg, I.1
Groschup, M.H.2
Pfaff, E.3
Priola, S.A.4
-
73
-
-
0025273876
-
Two alleles of a neural protein gene linked to scrapie in sheep
-
Goldmann W, Hunter N, Foster JD, Salbaum JM, Beyreuther K, et al. (1990) Two alleles of a neural protein gene linked to scrapie in sheep. Proc Natl Acad Sci U S A 87: 2476-2480.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 2476-2480
-
-
Goldmann, W.1
Hunter, N.2
Foster, J.D.3
Salbaum, J.M.4
Beyreuther, K.5
-
74
-
-
0030990920
-
PrP genotypes and experimental scrapie in orally inoculated Suffolk sheep in the United States
-
O'Rourke KI, Holyoak GR, Clark WW, Mickelson JR, Wang S, et al. (1997) PrP genotypes and experimental scrapie in orally inoculated Suffolk sheep in the United States. J Gen Virol 78 (Pt 4): 975-978.
-
(1997)
J Gen Virol
, vol.78
, Issue.Pt 4
, pp. 975-978
-
-
O'Rourke, K.I.1
Holyoak, G.R.2
Clark, W.W.3
Mickelson, J.R.4
Wang, S.5
-
75
-
-
0034534680
-
High frequency of mutations in four different disease genes in early-onset dementia
-
Finckh U, Muller-Thomsen T, Mann U, Eggers C, Marksteiner J, et al. (2000) High frequency of mutations in four different disease genes in early-onset dementia. Ann N Y Acad Sci 920: 100-106.
-
(2000)
Ann N Y Acad Sci
, vol.920
, pp. 100-106
-
-
Finckh, U.1
Muller-Thomsen, T.2
Mann, U.3
Eggers, C.4
Marksteiner, J.5
-
76
-
-
67349216125
-
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
-
Revesz T, Holton JL, Lashley T, Plant G, Frangione B, et al. (2009) Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies. Acta Neuropathol 118: 115-130.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 115-130
-
-
Revesz, T.1
Holton, J.L.2
Lashley, T.3
Plant, G.4
Frangione, B.5
-
77
-
-
0026552106
-
Creutzfeldt-Jakob disease cosegregates with the codon 178Asn PRNP mutation in families of European origin
-
Goldfarb LG, Brown P, Haltia M, Cathala F, McCombie WR, et al. (1992) Creutzfeldt-Jakob disease cosegregates with the codon 178Asn PRNP mutation in families of European origin. Ann Neurol 31: 274-281.
-
(1992)
Ann Neurol
, vol.31
, pp. 274-281
-
-
Goldfarb, L.G.1
Brown, P.2
Haltia, M.3
Cathala, F.4
McCombie, W.R.5
-
78
-
-
77957680268
-
Prospective 10-year surveillance of human prion diseases in Japan
-
Nozaki I, Hamaguchi T, Sanjo N, Noguchi-Shinohara M, Sakai K, et al. (2010) Prospective 10-year surveillance of human prion diseases in Japan. Brain 133: 3043-3057.
-
(2010)
Brain
, vol.133
, pp. 3043-3057
-
-
Nozaki, I.1
Hamaguchi, T.2
Sanjo, N.3
Noguchi-Shinohara, M.4
Sakai, K.5
-
79
-
-
0030773705
-
A prion-linked psychiatric disorder
-
Samaia HB, Mari JJ, Vallada HP, Moura RP, Simpson AJ, et al. (1997) A prion-linked psychiatric disorder. Nature 390: 241.
-
(1997)
Nature
, vol.390
, pp. 241
-
-
Samaia, H.B.1
Mari, J.J.2
Vallada, H.P.3
Moura, R.P.4
Simpson, A.J.5
-
80
-
-
78149300185
-
D178N, 129Val and N171S, 129Val genotype in a family with Creutzfeldt-Jakob disease
-
Appleby BS, Appleby KK, Hall RC, Wallin MT, (2010) D178N, 129Val and N171S, 129Val genotype in a family with Creutzfeldt-Jakob disease. Dement Geriatr Cogn Disord 30: 424-431.
-
(2010)
Dement Geriatr Cogn Disord
, vol.30
, pp. 424-431
-
-
Appleby, B.S.1
Appleby, K.K.2
Hall, R.C.3
Wallin, M.T.4
-
81
-
-
0028962532
-
Prion protein gene variation among primates
-
Schatzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB, (1995) Prion protein gene variation among primates. J Mol Biol 245: 362-374.
-
(1995)
J Mol Biol
, vol.245
, pp. 362-374
-
-
Schatzl, H.M.1
Da Costa, M.2
Taylor, L.3
Cohen, F.E.4
Prusiner, S.B.5
-
82
-
-
49749206702
-
Encephalopathy in mice produced by inoculation with scrapie brain material
-
Chandler RL, (1961) Encephalopathy in mice produced by inoculation with scrapie brain material. Lancet 1: 1378-1379.
-
(1961)
Lancet
, vol.1
, pp. 1378-1379
-
-
Chandler, R.L.1
|