A new transgenic mouse model of Gerstmann-Sträussler-Scheinker syndrome caused by the A117V mutation of PRNP

Journal of Neuroscience

Volumn 29, Issue 32, 2009, Pages 10072-10080

  Yang, Wenbin ^a   Cook, Julie ^a   Rassbach, Benjamin ^a   Lemus, Azucena ^b   DeArmond, Stephen J ^b   Mastrianni, James A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; PROTEINASE; THIOFLAVINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CAUDATE NUCLEUS; CELL VACUOLE; CEREBELLUM CORTEX; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DISEASE COURSE; GENE EXPRESSION; GENE MUTATION; GERSTMANN STRAUSSLER SCHEINKER SYNDROME; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MOUSE; MUTATIONAL ANALYSIS; NEOCORTEX; NEUROPATHOLOGY; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

ANIMALS; ATAXIA; BLOTTING, WESTERN; BRAIN; CREUTZFELDT-JAKOB SYNDROME; DISEASE MODELS, ANIMAL; GERSTMANN-STRAUSSLER-SCHEINKER DISEASE; HUMANS; KAPLAN-MEIERS ESTIMATE; MICE; MICE, TRANSGENIC; MUTATION, MISSENSE; PHENOTYPE; PRIONS; PRPC PROTEINS; PRPSC PROTEINS; THIAZOLES; TIME FACTORS;

EID: 68849129618     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2542-09.2009     Document Type: Article

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