Polymorphism in HIV-1 dependency factor PDE8A affects mRNA level and HIV-1 replication in primary macrophages

Virology

Volumn 420, Issue 1, 2011, Pages 32-42

  Bol, Sebastiaan M ^a   Booiman, Thijs ^a   Bunnik, Evelien M ^a   Moerland, Perry D ^b,c   van Dort, Karel ^a   Strauss, Jerome F ^d   Sieberer, Margit ^a   Schuitemaker, Hanneke ^a   Kootstra, Neeltje A ^a   van't Wout, Angélique B ^a  

^a SANQUIN RESEARCH   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c NETHERLANDS BIOINFORMATICS CENTRE   (Netherlands)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

HIV 1; HIV 1 dependency factor; Macrophage; PDE8A; RNAi; SNP

Indexed keywords

MESSENGER RNA; PHOSPHODIESTERASE; PHOSPHODIESTERASE 8A; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CONTROLLED STUDY; ENZYME POLYMORPHISM; GENE SEQUENCE; GENE SILENCING; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS GENOME; VIRUS IDENTIFICATION; VIRUS REPLICATION;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; CELL LINE; CELLS, CULTURED; GENETIC VARIATION; HIV INFECTIONS; HIV-1; HUMANS; MACROPHAGES; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 80053383322     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.08.013     Document Type: Article

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