Donor variation in in vitro HIV-1 susceptibility of monocyte-derived macrophages

Virology

Volumn 390, Issue 2, 2009, Pages 205-211

  Bol, Sebastiaan M ^a   van Remmerden, Yvonne ^a   Sietzema, Jantine G ^a   Kootstra, Neeltje A ^a   Schuitemaker, Hanneke ^a   van 't Wout, Angélique B ^a  

^a SANQUIN RESEARCH   (Netherlands)

Author keywords

CCR5; HIV 1; Host genetic variation; Macrophage; Monocyte

Indexed keywords

CHEMOKINE RECEPTOR CCR5;

ADULT; ARTICLE; BASE PAIRING; CONTROLLED STUDY; FEMALE; GENE DELETION; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; INFECTION RESISTANCE; INFECTION SENSITIVITY; MACROPHAGE; MALE; MONOCYTE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; VESICULAR STOMATITIS VIRUS; VIRUS ENTRY; VIRUS REPLICATION;

ADULT; CELLS, CULTURED; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HIV-1; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; RECEPTORS, CCR5; SEQUENCE DELETION; YOUNG ADULT;

HUMAN IMMUNODEFICIENCY VIRUS 1; VESICULAR STOMATITIS VIRUS;

EID: 67650045749     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.05.027     Document Type: Article

References (41)

1. Al-Jabri A.A., Lambkin R., and Oxford J.S. Lack of evidence for complete resistance of peripheral blood mononuclear cells to HIV-1 and HIV-2 infection. Viral. Immunol. 21 1 (2008) 83-90
2. Blaak H., Ran L.J., Rientsma R., and Schuitemaker H. Susceptibility of in vitro stimulated PBMC to infection with NSI HIV-1 is associated with levels of CCR5 expression and beta-chemokine production. Virology 267 2 (2000) 237-246
3. Bleiber G., May M., Martinez R., Meylan P., Ott J., Beckmann J.S., and Telenti A. Use of a combined ex vivo/in vivo population approach for screening of human genes involved in the human immunodeficiency virus type 1 life cycle for variants influencing disease progression. J. Virol. 79 20 (2005) 12674-12680
4. Carter C.A., and Ehrlich L.S. Cell biology of HIV-1 infection of macrophages. Annu. Rev. Microbiol. 62 (2008) 425-443
5. Chang J., Naif H.M., Li S., Sullivan J.S., Randle C.M., and Cunningham A.L. Twin studies demonstrate a host cell genetic effect on productive human immunodeficiency virus infection of human monocytes and macrophages in vitro. J. Virol. 70 11 (1996) 7792-7803
6. Chun T.W., Stuyver L., Mizell S.B., Ehler L.A., Mican J.A., Baseler M., Lloyd A.L., Nowak M.A., and Fauci A.S. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc. Natl. Acad. Sci. U. S. A. 94 24 (1997) 13193-13197
7. Ciuffi A., Bleiber G., Munoz M., Martinez R., Loeuillet C., Rehr M., Fischer M., Gunthard H.F., Oxenius A., Meylan P., Bonhoeffer S., Trono D., and Telenti A. Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection. J. Virol. 78 19 (2004) 10747-10754
8. Crowe S.M., and Sonza S. HIV-1 can be recovered from a variety of cells including peripheral blood monocytes of patients receiving highly active antiretroviral therapy: a further obstacle to eradication. J. Leukoc. Biol. 68 3 (2000) 345-350
9. Dean M., Carrington M., Winkler C., Huttley G.A., Smith M.W., Allikmets R., Goedert J.J., Buchbinder S.P., Vittinghoff E., Gomperts E., Donfield S., Vlahov D., Kaslow R., Saah A., Rinaldo C., Detels R., and O'Brien S.J. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 273 5283 (1996) 1856-1862
10. de Roda Husman A.M., Koot M., Cornelissen M., Keet I.P., Brouwer M., Broersen S.M., Bakker M., Roos M.T., Prins M., de Wolf F., Coutinho R.A., Miedema F., Goudsmit J., and Schuitemaker H. Association between CCR5 genotype and the clinical course of HIV-1 infection. Ann. Intern. Med. 127 10 (1997) 882-890
11. Eisert V., Kreutz M., Becker K., Konigs C., Alex U., Rubsamen-Waigmann H., Andreesen R., and von Briesen H. Analysis of cellular factors influencing the replication of human immunodeficiency virus type I in human macrophages derived from blood of different healthy donors. Virology 286 1 (2001) 31-44
12. Ellery P.J., Tippett E., Chiu Y.L., Paukovics G., Cameron P.U., Solomon A., Lewin S.R., Gorry P.R., Jaworowski A., Greene W.C., Sonza S., and Crowe S.M. The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J. Immunol. 178 10 (2007) 6581-6589
13. Finzi D., Hermankova M., Pierson T., Carruth L.M., Buck C., Chaisson R.E., Quinn T.C., Chadwick K., Margolick J., Brookmeyer R., Gallant J., Markowitz M., Ho D.D., Richman D.D., and Siliciano R.F. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278 5341 (1997) 1295-1300
14. Fouchier R.A., Brouwer M., Kootstra N.A., Huisman H.G., and Schuitemaker H. HIV-1 macrophage tropism is determined at multiple levels of the viral replication cycle. J. Clin. Invest. 94 5 (1994) 1806-1814
15. Igarashi T., Brown C.R., Endo Y., Buckler-White A., Plishka R., Bischofberger N., Hirsch V., and Martin M.A. Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): implications for HIV-1 infections of humans. Proc. Natl. Acad. Sci. U. S. A. 98 2 (2001) 658-663
16. Kootstra N.A., Zwart B.M., and Schuitemaker H. Diminished human immunodeficiency virus type 1 reverse transcription and nuclear transport in primary macrophages arrested in early G(1) phase of the cell cycle. J. Virol. 74 4 (2000) 1712-1717
17. Lama J., and Planelles V. Host factors influencing susceptibility to HIV infection and AIDS progression. Retrovirology 4 (2007) 52
18. Loeuillet C., Deutsch S., Ciuffi A., Robyr D., Taffe P., Munoz M., Beckmann J.S., Antonarakis S.E., and Telenti A. In vitro whole-genome analysis identifies a susceptibility locus for HIV-1. PLoS. Biol. 6 2 (2008) e32
19. Naif H.M., Li S., Alali M., Chang J., Mayne C., Sullivan J., and Cunningham A.L. Definition of the stage of host cell genetic restriction of replication of human immunodeficiency virus type 1 in monocytes and monocyte-derived macrophages by using twins. J. Virol. 73 6 (1999) 4866-4881
20. Nathans R., Cao H., Sharova N., Ali A., Sharkey M., Stranska R., Stevenson M., and Rana T.M. Small-molecule inhibition of HIV-1 Vif. Nat. Biotechnol. 26 10 (2008) 1187-1192
21. Nelson G.W., and O'Brien S.J. Using mutual information to measure the impact of multiple genetic factors on AIDS. J. Acquir. Immune. Defic. Syndr. 42 3 (2006) 347-354
22. O'Brien S.J., and Nelson G.W. Human genes that limit AIDS. Nat. Genet. 36 6 (2004) 565-574
23. Ometto L., Zanchetta M., Cabrelle A., Esposito G., Mainardi M., Chieco-Bianchi L., and De Rossi A. Restriction of HIV type 1 infection in macrophages heterozygous for a deletion in the CC-chemokine receptor 5 gene. AIDS Res. Hum. Retroviruses 15 16 (1999) 1441-1452
24. Paxton W.A., Kang S., Liu R., Landau N.R., Gingeras T.R., Wu L., Mackay C.R., and Koup R.A. HIV-1 infectability of CD4+ lymphocytes with relation to beta-chemokines and the CCR5 coreceptor. Immunol. Lett. 66 1-3 (1999) 71-75
25. Pesenti E., Pastore C., Lillo F., Siccardi A.G., Vercelli D., and Lopalco L. Role of CD4 and CCR5 levels in the susceptibility of primary macrophages to infection by CCR5-dependent HIV type 1 isolates. AIDS Res. Hum. Retroviruses 15 11 (1999) 983-987
26. Quillent C., Oberlin E., Braun J., Rousset D., Gonzalez-Canali G., Metais P., Montagnier L., Virelizier J.L., Arenzana-Seisdedos F., and Beretta A. HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene. Lancet 351 9095 (1998) 14-18
27. Rana S., Besson G., Cook D.G., Rucker J., Smyth R.J., Yi Y., Turner J.D., Guo H.H., Du J.G., Peiper S.C., Lavi E., Samson M., Libert F., Liesnard C., Vassart G., Doms R.W., Parmentier M., and Collman R.G. Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation. J. Virol. 71 4 (1997) 3219-3227
28. Samson M., Libert F., Doranz B.J., Rucker J., Liesnard C., Farber C.M., Saragosti S., Lapoumeroulie C., Cognaux J., Forceille C., Muyldermans G., Verhofstede C., Burtonboy G., Georges M., Imai T., Rana S., Yi Y., Smyth R.J., Collman R.G., Doms R.W., Vassart G., and Parmentier M. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382 6593 (1996) 722-725
29. Sayah D.M., Sokolskaja E., Berthoux L., and Luban J. Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature 430 6999 (2004) 569-573
30. Schmidtmayerova H., Nuovo G.J., and Bukrinsky M. Cell proliferation is not required for productive HIV-1 infection of macrophages. Virology 232 2 (1997) 379-384
31. Schuitemaker H., Kootstra N.A., Koppelman M.H., Bruisten S.M., Huisman H.G., Tersmette M., and Miedema F. Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages. J. Clin. Invest. 89 4 (1992) 1154-1160
32. Schuitemaker H., Kootstra N.A., Fouchier R.A., Hooibrink B., and Miedema F. Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity. EMBO J. 13 24 (1994) 5929-5936
33. Stremlau M., Owens C.M., Perron M.J., Kiessling M., Autissier P., and Sodroski J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 427 6977 (2004) 848-853
34. Telenti A., and Goldstein D.B. Genomics meets HIV-1. Nat. Rev. Microbiol. 4 11 (2006) 865-873
35. Tersmette M., Winkel I.N., Groenink M., Gruters R.A., Spence R.P., Saman E., Van Der Groen G., Miedema F., and Huisman J.G. Detection and subtyping of HIV-1 isolates with a panel of characterized monoclonal antibodies to HIV p24gag. Virology 171 1 (1989) 149-155
36. Thomas S.M., Tse D.B., Ketner D.S., Rochford G., Meyer D.A., Zade D.D., Halkitis P.N., Nadas A., Borkowsky W., and Marmor M. CCR5 expression and duration of high risk sexual activity among HIV-seronegative men who have sex with men. Aids 20 14 (2006) 1879-1883
37. van Griensven G.J., Tielman R.A., Goudsmit J., van der Noordaa J., de Wolf F., de Vroome E.M., and Coutinho R.A. Risk factors and prevalence of HIV antibodies in homosexual men in the Netherlands. Am. J. Epidemiol. 125 6 (1987) 1048-1057
38. van 't Wout A.B., Schuitemaker H., and Kootstra N.A. Isolation and propagation of HIV-1 on peripheral blood mononuclear cells. Nat. Protoc. 3 3 (2008) 363-370
39. Venkatesan S., Petrovic A., Van Ryk D.I., Locati M., Weissman D., and Murphy P.M. Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration. J. Biol. Chem. 277 3 (2002) 2287-2301
40. Wang X., Ye L., Hou W., Zhou Y., Wang Y.J., Metzger D.S., and Ho W.Z. Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infection. Blood 113 3 (2009) 671-674
41. Wu L., Paxton W.A., Kassam N., Ruffing N., Rottman J.B., Sullivan N., Choe H., Sodroski J., Newman W., Koup R.A., and Mackay C.R. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185 9 (1997) 1681-1691