Power of selective genotyping in genetic association analyses of quantitative traits

Behavior Genetics

Volumn 30, Issue 2, 2000, Pages 141-146

  Van Gestel, Sofie ^a   Houwing Duistermaat, Jeanine J ^b   Adolfsson, Rolf ^c   Van Duijn, Cornelia M ^b   Van Broeckhoven, Christine ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

Association analysis; Power; QTL; Selective genotyping

Indexed keywords

ALLELE; ARTICLE; CALCULATION; GENE FREQUENCY; GENOTYPE; INHERITANCE; NONHUMAN; PHENOTYPE; QUANTITATIVE TRAIT;

CHROMOSOME MAPPING; GENOTYPE; HUMANS; MODELS, GENETIC; PHENOTYPE; QUANTITATIVE TRAIT, HERITABLE; SELECTION (GENETICS);

EID: 0033840757     PISSN: 00018244     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1001907321955     Document Type: Article

References (10)

1. Extreme selection strategies in gene mapping studies of oligogenic quantitative traits do not always increase power
2. Dopamine markers and general cognitive ability
3. The serotonin transporter gene and peer-rated neuroticism
4. Selective genotyping for determination of linkage between a marker locus and a quantitative trait locus
5. Tests and estimates of allelic association in complex inheritance
6. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
7. No association between general cognitive ability and the A1 allele of the D2 dopamine receptor gene
8. DNA markers associated with high versus low IQ: The IQ quantitative trait loci (QTL) project
9. No association between Novelty Seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging Participants