Minor groove binders and drugs targeting proteins cover complementary regions in chemical shape space

Journal of Chemical Information and Modeling

Volumn 51, Issue 9, 2011, Pages 2223-2232

  Fuchs, Julian E ^a   Spitzer, Gudrun M ^a   Javed, Ameera ^a   Biela, Adam ^b   Kreutz, Christoph ^a   Wellenzohn, Bernd ^c   Liedl, Klaus R ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; PROTEINS;

AROMATIC RINGS; COMPUTATIONAL APPROACH; ENRICHMENT RATE; EXPERIMENTAL TESTING; POSITIVE CHARGES; THERAPEUTIC POTENTIALS; TRUE POSITIVE; VIRTUAL SCREENING;

BINDERS;

DNA; DRUG; PROTEIN;

ARTICLE; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; PROTEIN DATABASE; ULTRAVIOLET SPECTROPHOTOMETRY; VALIDATION STUDY;

CALORIMETRY; DATABASES, PROTEIN; DNA; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; PROTEINS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 80053309865     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci200237c     Document Type: Article

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