A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-Bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity

Biochemistry

Volumn 35, Issue 18, 1996, Pages 5655-5661

  Laughton, Charles A ^a   Tanious, Fanal ^b   Nunn, Christine M ^a   Boykin, David W ^b   David Wilson, W ^b   Neidle, Stephen ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 BIS(4 GUANYLPHENYL)FURAN; DIMINAZENE ACETURATE; DNA; FURAN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; DNA DRUG COMPLEX; DNA SEQUENCE; DNA STRUCTURE; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG STRUCTURE; FLUORESCENCE; MOLECULAR MODEL; PRIORITY JOURNAL; SCATCHARD PLOT; ULTRAVIOLET SPECTROPHOTOMETRY;

AMIDINES; ANIMALS; ANTIFUNGAL AGENTS; BASE SEQUENCE; BENZAMIDINES; BINDING SITES; DIMINAZENE; DNA; INTERCALATING AGENTS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; PNEUMOCYSTIS; RATS; SPECTROPHOTOMETRY; THERMODYNAMICS; TRYPANOCIDAL AGENTS;

EID: 0029928846     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952162r     Document Type: Article

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