메뉴 건너뛰기




Volumn 59, Issue 18, 2011, Pages 9885-9891

Effects of sesamol on apoptosis and steroidogenesis in MA-10 mouse Leydig tumor cells

Author keywords

apoptosis; Leydig; MA 10; sesamol; steroidogenesis

Indexed keywords

ANTITUMOR EFFECT; APOPTOTIC; CASPASE-3; CASPASES; CELL CYCLE; CELL VIABILITY; FLOW CYTOMETRY ANALYSIS; IMMUNOBLOTTING; LEYDIG; MA-10; MORPHOLOGICAL OBSERVATIONS; PROTEIN EXPRESSIONS; PURE COMPOUNDS; SESAMOL; STEROIDOGENESIS; STEROIDOGENIC ACUTE REGULATORY PROTEINS; TREATMENT DURATION; TUMOR CELL LINES; TUMOR CELLS;

EID: 80053095691     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2021539     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 33644747334 scopus 로고    scopus 로고
    • Development and evaluation of sesamol as an antiaging agent
    • DOI 10.1111/j.1365-4632.2004.02537.x
    • Sharma, S.; Kaur, I. P. Development and evaluation of sesamol as an antiaging agent Int. J. Dermatol. 2006, 45, 200-208 (Pubitemid 43337630)
    • (2006) International Journal of Dermatology , vol.45 , Issue.3 , pp. 200-208
    • Sharma, S.1    Kaur, I.P.2
  • 3
    • 15944362568 scopus 로고    scopus 로고
    • Radioprotective effect of sesamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes
    • DOI 10.1016/j.tox.2004.12.009
    • Prasad, N. R.; Menon, V. P.; Vasudev, V.; Puqalendi, K. V. Radioprotective effect of sesamol on gamma-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes Toxicology 2005, 209, 225-235 (Pubitemid 40431682)
    • (2005) Toxicology , vol.209 , Issue.3 , pp. 225-235
    • Prasad, N.R.1    Menon, V.P.2    Vasudev, V.3    Pugalendi, K.V.4
  • 4
    • 85006962506 scopus 로고    scopus 로고
    • The Sesame Seed Oil Constituent, Sesamol, Induces Growth Arrest and Apoptosis of Cancer and Cardiovascular Cells
    • DOI 10.1196/annals.1299.068
    • Jacklin, A.; Ratledge, C.; Welham, K.; Bilko, D.; Newton, C. J. The sesame seed oil constituent, sesamol, induces growth arrest and apoptosis of cancer and cardiovascular cells Ann. N.Y. Acad. Sci. 2003, 1010, 374-380 (Pubitemid 38265010)
    • (2003) Annals of the New York Academy of Sciences , vol.1010 , pp. 374-380
    • Jacklin, A.1    Ratledge, C.2    Welham, K.3    Bilko, D.4    Newton, C.J.5
  • 5
    • 65549089618 scopus 로고    scopus 로고
    • Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: Potent cytotoxicity of resveratrol to normal cells
    • Fujimoto, A.; Sakanashi, Y.; Matsui, H.; Oyama, T.; Nishimura, Y.; Masuda, T.; Oyama, Y. Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: potent cytotoxicity of resveratrol to normal cells Basic Clin. Pharmacol. Toxicol. 2009, 104, 455-462
    • (2009) Basic Clin. Pharmacol. Toxicol. , vol.104 , pp. 455-462
    • Fujimoto, A.1    Sakanashi, Y.2    Matsui, H.3    Oyama, T.4    Nishimura, Y.5    Masuda, T.6    Oyama, Y.7
  • 6
    • 27444441555 scopus 로고    scopus 로고
    • Sesamol induces nitric oxide release from human umbilical vein endothelial cells
    • DOI 10.1007/s11745-005-1456-3, L9718
    • Chen, P. R.; Tsai, C. E.; Chang, H.; Liu, T. L.; Lee, C. C. Sesamol induces nitric oxide release from human umbilical vein endothelial cells Lipids 2005, 40, 955-961 (Pubitemid 41531945)
    • (2005) Lipids , vol.40 , Issue.9 , pp. 955-961
    • Chen, P.-R.1    Tsai, C.E.2    Chang, H.3    Liu, T.-L.4    Lee, C.-C.5
  • 7
    • 0030459714 scopus 로고    scopus 로고
    • Nitric oxide inhibits leydig cell steroidogenesis
    • DOI 10.1210/en.137.12.5337
    • Del Punta, K; Charreau, E,H; Pignataro, O,P. Nitric oxide inhibits Leydig cell steroidogenesis Endocrinology 1996, 137, 5337-5343 (Pubitemid 26423094)
    • (1996) Endocrinology , vol.137 , Issue.12 , pp. 5337-5343
    • Del Punta, K.1    Charreau, E.H.2    Pignataro, O.P.3
  • 8
    • 0034779903 scopus 로고    scopus 로고
    • Inhibition of steroidogenesis in Leydig cells by exogenous nitric oxide occurs independently of steroidogenic acute regulatory protein (StAR) MRNA
    • DOI 10.1080/014850101753145915
    • Dobashi, M.; Fujisawa, M.; Yamazaki, T.; Okuda, Y.; Kanzaki, M.; Tatsumi, N.; Tsuji, T.; Okada, H.; Kamidono, S. Inhibition of steroidogenesis in Leydig cells by exogenous nitric oxide occurs independently of steroidogenic acute regulatory protein (star) mRNA Arch. Androl. 2001, 47, 203-209 (Pubitemid 32980666)
    • (2001) Archives of Andrology , vol.47 , Issue.3 , pp. 203-209
    • Dobashi, M.1    Fujisawa, M.2    Yamazaki, T.3    Okuda, Y.4    Kanzaki, M.5    Tatsumi, N.6    Tsuji, T.7    Okada, H.8    Kamidono, S.9
  • 9
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J. F.; Wyllie, A. H.; Currie, A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br. J. Cancer 1972, 26, 239-257
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 10
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie, A. H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation Nature 1980, 284, 555-556 (Pubitemid 10070336)
    • (1980) Nature , vol.284 , Issue.5756 , pp. 555-556
    • Wyllie, A.H.1
  • 11
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller, H. Mechanisms and genes of cellular suicide Science 1995, 267, 1445-1449
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 12
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns, V.; Yuan, J. Proteases to die for Genes Dev. 1998, 12, 1551-1570 (Pubitemid 28299508)
    • (1998) Genes and Development , vol.12 , Issue.11 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 13
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry, N. A.; Lazebnik, Y. Caspases: enemies within Science 1998, 281, 1312-1316 (Pubitemid 28406817)
    • (1998) Science , vol.281 , Issue.5381 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 14
    • 0031615875 scopus 로고    scopus 로고
    • Autoproteolytic activation of pro-caspases by oligomerization
    • Yang, X.; Chang, H. Y.; Baltimore, D. Autoproteolytic activation of pro-caspases by oligomerization Mol. Cell 1998, 1, 319-325 (Pubitemid 128378672)
    • (1998) Molecular Cell , vol.1 , Issue.2 , pp. 319-325
    • Yang, X.1    Chang, H.Y.2    Baltimore, D.3
  • 15
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li, H.; Zhu, H.; Xu, C. J.; Yuan, J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 1998, 94, 491-501 (Pubitemid 28391865)
    • (1998) Cell , vol.94 , Issue.4 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.-J.3    Yuan, J.4
  • 16
    • 0035831473 scopus 로고    scopus 로고
    • Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis
    • Slee, E. A.; Adrian, C.; Martin, S. J. Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis J. Biol. Chem. 2001, 276, 7320-7326
    • (2001) J. Biol. Chem. , vol.276 , pp. 7320-7326
    • Slee, E.A.1    Adrian, C.2    Martin, S.J.3
  • 17
    • 0025811787 scopus 로고
    • Evidence for compartmentalization of adenosine 3′,5′- monophosphate (cAMP)-dependent protein kinases in rat Leydig cells using site-selective cAMP analogs
    • Moger, W. H. Evidence for compartmentalization of adenosine 3′,5′-monophosphate (cAMP)-dependent protein kinases in rat Leydig cells using site-selective cAMP analogs Endocrinology 1991, 128, 1414-1418
    • (1991) Endocrinology , vol.128 , pp. 1414-1418
    • Moger, W.H.1
  • 18
    • 0025941096 scopus 로고
    • The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors
    • Stocco, D. M.; Sodeman, T. C. The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors J. Biol. Chem. 1991, 266, 19731-19738 (Pubitemid 21908288)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.29 , pp. 19731-19738
    • Stocco, D.M.1    Sodeman, T.C.2
  • 19
    • 0038630960 scopus 로고    scopus 로고
    • START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells
    • DOI 10.1016/S0303-7207(03)00063-7
    • Strauss, J. F, III.; Kishida, T.; Christenson, L. K.; Fujimoto, T.; Hiroi, H. START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells Mol. Cell. Endocrinol. 2003, 202, 59-65 (Pubitemid 36603365)
    • (2003) Molecular and Cellular Endocrinology , vol.202 , Issue.1-2 , pp. 59-65
    • Strauss III, J.F.1    Kishida, T.2    Christenson, L.K.3    Fujimoto, T.4    Hiroi, H.5
  • 20
    • 0034899563 scopus 로고    scopus 로고
    • Tracking the role of a StAR in the sky of the new millennium
    • DOI 10.1210/me.15.8.1245
    • Stocco, D. M. Tracking the role of a star in the sky of the new millennium Mol. Endocrinol. 2001, 15, 1245-1254 (Pubitemid 32703474)
    • (2001) Molecular Endocrinology , vol.15 , Issue.8 , pp. 1245-1254
    • Stocco, D.M.1
  • 21
    • 0035919207 scopus 로고    scopus 로고
    • Origin, differentiation and regulation of fetal and adult Leydig cells
    • DOI 10.1016/S0303-7207(01)00461-0, PII S0303720701004610
    • Habert, R.; Lejeune, H.; Saez, J. M. Origin, differentiation and regulation of fetal and adult Leydig cells Mol. Cell. Endocrinol. 2001, 179, 47-74 (Pubitemid 32564952)
    • (2001) Molecular and Cellular Endocrinology , vol.179 , Issue.1-2 , pp. 47-74
    • Habert, R.1    Lejeune, H.2    Saez, J.M.3
  • 22
    • 79955819635 scopus 로고    scopus 로고
    • The in vivo and in vitro stimulatory effects of cordycepin on mouse Leydig cell steroidogenesis
    • Leu, S. F.; Poon, S. L.; Pao, H. Y.; Huang, B. M. The in vivo and in vitro stimulatory effects of cordycepin on mouse Leydig cell steroidogenesis Biosci Biotechnol Biochem 2011, 75, 723-731
    • (2011) Biosci Biotechnol Biochem , vol.75 , pp. 723-731
    • Leu, S.F.1    Poon, S.L.2    Pao, H.Y.3    Huang, B.M.4
  • 23
    • 0027132475 scopus 로고
    • The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells
    • DOI 10.1210/en.133.6.2827
    • Stocco, D. M.; Wells, J.; Clark, B. J. The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells Endocrinology 1993, 133, 2827-2832 (Pubitemid 24000742)
    • (1993) Endocrinology , vol.133 , Issue.6 , pp. 2827-2832
    • Stocco, D.M.1    Wells, J.2    Clark, B.J.3
  • 24
    • 0037661090 scopus 로고    scopus 로고
    • Reactive oxygen disrupts mitochondria in MA-10 tumor leydig cells and inhibits steroidogenic acute regulatory (STAR) protein and steroidogenesis
    • DOI 10.1210/en.2002-0090
    • Diemer, T.; Allan, J. A.; Hales, K. H.; Hales, D. B. Reactive oxygen disrupts mitochondria in MA-10 tumor leydig cells and inhibits steroidogenic acute regulatory (StAR) protein and steroidogenesis Endocrinology 2003, 144, 2882-2891 (Pubitemid 36819890)
    • (2003) Endocrinology , vol.144 , Issue.7 , pp. 2882-2891
    • Diemer, T.1    Allen, J.A.2    Hales, K.H.3    Hales, D.B.4
  • 25
    • 80052652315 scopus 로고    scopus 로고
    • The effect of cordycepin on steroidogenesis and apoptosis in MA-10 mouse Leydig tumor cells
    • in press.
    • Pan, B. S.; Lin, C. Y.; Huang, B. M. The effect of cordycepin on steroidogenesis and apoptosis in MA-10 mouse Leydig tumor cells. Evid. Based Complement. Alternat. Med. 2011, in press.
    • (2011) Evid. Based Complement. Alternat. Med.
    • Pan, B.S.1    Lin, C.Y.2    Huang, B.M.3
  • 26
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flowcytometry
    • Nicoletti, I.; Migliorati, G.; Pagliacci, M. C.; Grignani, F.; Riccardi, C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flowcytometry J. Immunol. Methods 1991, 139, 271-279
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 27
    • 13844297624 scopus 로고    scopus 로고
    • Free radical scavenging and apoptotic effects of cordycepin sinensis fractionated by supercritical carbon dioxide
    • Wang, B. J.; Won, S. J.; Yu, Z. R.; Su, C. L. Free radical scavenging and apoptotic effects of cordycepin sinensis fractionated by supercritical carbon dioxide Food Chem. Toxicol. 2005, 43, 543-552
    • (2005) Food Chem. Toxicol. , vol.43 , pp. 543-552
    • Wang, B.J.1    Won, S.J.2    Yu, Z.R.3    Su, C.L.4
  • 29
    • 0037119470 scopus 로고    scopus 로고
    • The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation
    • Kim, G. Y.; Mercer, S. E.; Ewton, D. Z.; Yan, Z.; Jin, K.; Friedman, E. The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation J. Biol. Chem. 2002, 277, 29792-29802
    • (2002) J. Biol. Chem. , vol.277 , pp. 29792-29802
    • Kim, G.Y.1    Mercer, S.E.2    Ewton, D.Z.3    Yan, Z.4    Jin, K.5    Friedman, E.6
  • 30
    • 77956176922 scopus 로고    scopus 로고
    • Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: A possible cytotoxicity of oxidized antioxidant
    • Fujimoto, A.; Shingai, Y.; Oyama, T. B.; Kawanai, T.; Hashimoto, E.; Koizumi, K.; Kimura, K.; Masuda, T.; Oyama, Y. Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant Toxicol. in Vitro 2010, 24, 1720-1726
    • (2010) Toxicol. in Vitro , vol.24 , pp. 1720-1726
    • Fujimoto, A.1    Shingai, Y.2    Oyama, T.B.3    Kawanai, T.4    Hashimoto, E.5    Koizumi, K.6    Kimura, K.7    Masuda, T.8    Oyama, Y.9
  • 31
    • 79951508964 scopus 로고    scopus 로고
    • Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis
    • Kumar, C. M.; Sathisha, U. V.; Dharmesh, S.; Rao, A. G.; Singh, S. A. Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis Biochimie 2011, 93, 562-569
    • (2011) Biochimie , vol.93 , pp. 562-569
    • Kumar, C.M.1    Sathisha, U.V.2    Dharmesh, S.3    Rao, A.G.4    Singh, S.A.5
  • 32
    • 1942508859 scopus 로고    scopus 로고
    • Upregulation of steroidogenic enzymes and ovarian 17beta-estradiol in human granulosa-lutein cells by Cordyceps sinensis mycelium
    • Huang, B. M.; Hsiao, K. Y.; Chuang, P. C.; Wu, M. H.; Pan, H. A.; Tsai, S. J. Upregulation of steroidogenic enzymes and ovarian 17beta-estradiol in human granulosa-lutein cells by Cordyceps sinensis mycelium Biol. Reprod. 2004, 70, 1358-1364
    • (2004) Biol. Reprod. , vol.70 , pp. 1358-1364
    • Huang, B.M.1    Hsiao, K.Y.2    Chuang, P.C.3    Wu, M.H.4    Pan, H.A.5    Tsai, S.J.6
  • 33
    • 0037436751 scopus 로고    scopus 로고
    • Effects of amphetamine on steroidogenesis in MA-10 mouse Leydig tumor cells
    • Chen, L. Y.; Huang, Y. L.; Liu, M. Y.; Leu, S. F.; Huang, B. M. Effects of amphetamine on steroidogenesis in MA-10 mouse Leydig tumor cells Life Sci. 2003, 72, 1983-1995
    • (2003) Life Sci. , vol.72 , pp. 1983-1995
    • Chen, L.Y.1    Huang, Y.L.2    Liu, M.Y.3    Leu, S.F.4    Huang, B.M.5
  • 34
    • 74149094419 scopus 로고    scopus 로고
    • Mitochondrial cholesterol transporter, StAR, inhibits human THP-1 monocyte-derived macrophage apoptosis
    • Bai, Q.; Li, X.; Ning, Y.; Zhao, F.; Yin, L. Mitochondrial cholesterol transporter, StAR, inhibits human THP-1 monocyte-derived macrophage apoptosis Lipids 2010, 45, 29-36
    • (2010) Lipids , vol.45 , pp. 29-36
    • Bai, Q.1    Li, X.2    Ning, Y.3    Zhao, F.4    Yin, L.5
  • 35
    • 79952375180 scopus 로고    scopus 로고
    • Effects of varicocele on testosterone, apoptosis and expression of StAR mRNA in rat Leydig cells
    • Luo, D. Y.; Yang, G.; Liu, J. J.; Yang, Y. R.; Dong, Q. Effects of varicocele on testosterone, apoptosis and expression of StAR mRNA in rat Leydig cells Asian J. Androl. 2011, 13, 287-291
    • (2011) Asian J. Androl. , vol.13 , pp. 287-291
    • Luo, D.Y.1    Yang, G.2    Liu, J.J.3    Yang, Y.R.4    Dong, Q.5
  • 36
    • 0034991034 scopus 로고    scopus 로고
    • Signalling apoptosis: A radical approach
    • DOI 10.1179/135100001101536085
    • Carmody, R. J.; Cotter, T. G. Signalling apoptosis: A radical approach Redox. Rep. 2001, 6, 77-90 (Pubitemid 32519815)
    • (2001) Redox Report , vol.6 , Issue.2 , pp. 77-90
    • Carmody, R.J.1    Cotter, T.G.2
  • 37
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • DOI 10.1016/j.drup.2004.01.004
    • Pelicano, H.; Carney, D.; Huang, P. ROS stress in cancer cells and therapeutic implications Drug Resist. Updat. 2004, 7, 97-110 (Pubitemid 38736063)
    • (2004) Drug Resistance Updates , vol.7 , Issue.2 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 38
    • 33644747334 scopus 로고    scopus 로고
    • Development and evaluation of sesamol as an antiaging agent
    • DOI 10.1111/j.1365-4632.2004.02537.x
    • Sharma, S.; Kaur, I. P. Development and evaluation of sesamol as an antiaging agent Int. J. Dermatol. 2006, 45, 200-208 (Pubitemid 43337630)
    • (2006) International Journal of Dermatology , vol.45 , Issue.3 , pp. 200-208
    • Sharma, S.1    Kaur, I.P.2
  • 39
    • 4344560306 scopus 로고    scopus 로고
    • Sesame lignans enhance antioxidant activity of vitamin E in lipid peroxidation systems
    • DOI 10.1023/B:MCBI.0000038235.01389.a9
    • Ghafoorunissa.; Hemalatha, S.; Rao, M. V. Sesamol lignans enhance antioxidant activity of vitamin E in lipid peroxidation systems Mol. Cell. Biochem. 2004, 262, 195-202 (Pubitemid 39158069)
    • (2004) Molecular and Cellular Biochemistry , vol.262 , Issue.1-2 , pp. 195-202
    • Ghafoorunissa, A.1    Hemalatha, S.2    Rao, M.V.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.