Inhibition of steroidogenesis in Leydig cells by exogenous nitric oxide occurs independently of steroidogenic acute regulatory protein (StAR) MRNA

Archives of Andrology

Volumn 47, Issue 3, 2001, Pages 203-209

  Dobashi, M ^a   Fujisawa, M ^a   Yamazaki, T ^a   Okuda, Y ^a   Kanzaki, M ^a   Tatsumi, N ^a   Tsuji, T ^a   Okada, H ^a   Kamidono, S ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Leydig cells; Nitric oxide; Steroidogenic acute regulatory protein; Testosterone

Indexed keywords

COMPLEMENTARY DNA; LUTEINIZING HORMONE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; HORMONAL REGULATION; LEYDIG CELL; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPRODUCTION; STEROIDOGENESIS; TESTOSTERONE BLOOD LEVEL;

ANIMALS; BLOTTING, NORTHERN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TESTOSTERONE;

EID: 0034779903     PISSN: 01485016     EISSN: None     Source Type: Journal    
DOI: 10.1080/014850101753145915     Document Type: Article

References (23)

1. Effects of nitric oxide-related agents on rat testicular function
2. Inhibition of the morphine withdrawal syndrome by a nitric oxide synthase inhibitor, NG-nitro-L-arginine methyl ester
3. Single-step method of RNA isolation by scidguanidium thiocynatephenol-chloroform extraction
4. Effect of nitric oxide on rat adrenal zona fasciculata steroidogenesis
5. Nitric oxide inhibits Leydig cell steroidogenesis
6. 15N]nitrate in biological fluids
7. Effect of sodium nitroprusside on sperm motility, viability, and lipid peroxidation
8. G-methy-L-arginine inhibits tumor necrosis factor-induced hypotension: Implications for the involvement of nitric oxide
9. Growth hormone regulates steroidogenic acute regulatory protein expression and steroidogenesis in Leydig cell progenitors
10. Nitric oxide inhibits steroidogenesis in cultured porcine granulosa cells
11. Nitric oxide: Physiology, pathophysiology, and pharmacology
12. Nitric oxide as a secretory product of mammalian
13. Nitric oxide production by cultured rat Leydig cells
14. Effect of nitric oxide on human spermatozoa: Evidence that nitric oxide decreases sperm motility and induces sperm toxicity
15. Inhibition of insulin secretion by interleukin-1b and tumor necrosis factor-a via an L-arginine-dependent nitric oxide generating mechanism
16. Regulation of the acute production of steroids in steroidogenic cells
17. Preliminary communication: Possible role of reactive nitrogen intermediates in leucocyte-mediated sperm dysfunction
18. Interleukin-1 inhibits Leydig cells steroidogenesis without affecting steroidogenic acute regulatory protein messenger ribonucleic acid or protein levels
19. Interferon-γ inhibits the steroidogenic acute regulatory protein messenger ribonucleic acid expression and protein levels in primary culture of rat Leydig cells
20. Nitric oxide inhibition of human sperm motility
21. Evidence to suggest nitric oxide is an interstitial regulator of Leydig cell steroidogenesis
22. Interleukin-1b-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
23. Low level of nitric oxide promotes human sperm capacitation in vitro