Defective leptin-AMP-dependent kinase pathway induces nitric oxide release and contributes to mitochondrial dysfunction and obesity in ob/ob mice

Antioxidants and Redox Signaling

Volumn 15, Issue 9, 2011, Pages 2395-2406

  Finocchietto, Paola V ^a   Holod, Silvia ^a   Barreyro, Fernando ^a   Peralta, Jorge G ^a   Alippe, Yael ^a   Giovambattista, Andrés ^b,c   Carreras, María C ^a,c   Poderoso, Juan J ^a,c  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADENYLATE KINASE; CITRULLINE; CYTOCHROME C OXIDASE; LEPTIN; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROTEIN KINASE B BETA;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSENSOR; CONCENTRATION (PARAMETERS); CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FAT CONTENT; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FLOW CYTOMETRY; HYPOLEPTINEMIA; INSULIN RESISTANCE; LEPTIN DEFICIENCY; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NITRATION; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; STEADY STATE; WESTERN BLOTTING;

ADENYLATE KINASE; ANIMALS; BLOTTING, WESTERN; FATTY ACIDS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; OBESITY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MUS;

EID: 80052971882     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2010.3857     Document Type: Article

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