Rapid transformation of white adipocytes into fat-oxidizing machines

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 7, 2004, Pages 2058-2063

  Orci, Lelio ^a   Cook, William S ^b   Ravazzola, Mariella ^a   Wang, May Yun ^b   Park, Byung Hyun ^b   Montesano, Roberto ^a   Ungert, Roger H ^b,c  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; BIOLOGICAL MARKER; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEPTIN; LIPID; MESSENGER RNA; OXIDIZING AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2;

ADENOVIRUS; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASEMENT MEMBRANE; BODY FAT; CHEMISTRY; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYMOLOGY; EXTRACELLULAR MATRIX; FATTY ACID OXIDATION; GENE EXPRESSION REGULATION; GENETICS; HYPERLIPIDEMIA; KETOGENESIS; LIPID OXIDATION; METABOLISM; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; PATHOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; UPREGULATION; WHITE ADIPOSE TISSUE;

ADENOVIRIDAE; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BIOLOGICAL MARKERS; GENE EXPRESSION REGULATION; HYPERLIPIDEMIAS; LEPTIN; LIPID METABOLISM; MITOCHONDRIA; OXIDANTS; OXIDATION-REDUCTION; RATS; RATS, ZUCKER; RNA, MESSENGER; TRANSCRIPTION FACTORS;

ADENOVIRIDAE; ANIMALIA;

EID: 1242274390     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0308258100     Document Type: Article

References (27)

1. Chen, G., Koyama, K., Yuan, X., Lee, Y., Zhou, Y. T., O'Doherty, R., Newgard, C. B. & Unger, R. H. (1996) Proc. Natl. Acad. Sci. USA 93, 14795-14799.
2. Shimabukuro, M., Koyama, K., Chen, G., Wang, M. Y., Trieu, F., Lee, Y., Newgard, C. B. & Unger, R. H. (1997) Proc. Natl. Acad. Sci. USA 94, 4637-4641.
3. Cahill, G. F., Jr., Aoki, T. T. & Ruderman, N. B. (1973) Trans. Am. Clin. Climatol. Assn. 84, 184-202.
4. Zhou, Y. T., Shimabukuro, M., Koyama, K., Lee, Y., Wang, M. Y., Trieu, F., Newgard, C. B. & Unger, R. H. (1997) Proc. Natl. Acad. Sci. USA 94, 6386-6390.
5. Wang, M. Y., Lee, Y. & Unger, R. H. (1999) J. Biol. Chem. 274, 17541-17544.
6. Liou, W., Geuze, H. J. & Slot, J. W. (1996) Histochem. Cell Biol. 106, 41-58.
7. Bustin, A. (2000) J. Mol. Endocrinol. 25, 169-193.
8. Pierleoni, C., Verdenelli, F., Castellucci, M. & Cinti, S. (1998) Eur. J. Histochem. 42, 183-188.
9. Sternlicht, M. D. & Werb, Z. (2001) Annu. Rev. Cell Dev. Biol. 17, 463-516.
10. Lohikangas, L., Gullberg, D. & Johansson, S. (2001) Exp. Cell Res. 265, 135-144.
11. Zhou, Z., Yon Toh, S., Chen, Z., Guo, K., Ng, C. P., Ponniah, S., Lin, S. C., Hong, W. & Li, P. (2003) Nat. Genet. 35, 49-56.
12. Lee, Y., Yu, X., Gonzales, F., Mangelsdorf, D. J., Wang, M. Y., Richardson, C., Witters, L. A. & Unger, R. H. (2002) Proc. Natl. Acad. Sci. USA 99, 11848-11853.
13. Wang, Y.-X., Lee, C.-H., Tiep, S., Yu, R., Ham, J., Kang, H. & Evans, R. M. (2003) Cell 113, 159-190.
14. Nakae, J., Kitamura, T., Kitamura, Y., Biggs, W. H., III, Arden, K. C. & Accili, D. (2003) Dev. Cell 4, 119-129.
15. Cederberg, A., Gronning, L. M., Ahren, B., Tasken, K., Carlsson, P. & Enerback, S. (2001) Cell 106, 563-573.
16. McGarry, J. D., Mannaerts, G. P. & Foster, D. W. (1977) J. Clin. Invest. 60, 265-270.
17. Hardie, D. G. (2003) Endocrinology 144, 5179-5183.
18. Saha, A. K. & Ruderman, N. B. (2003) Mol. Cell Biochem. 253, 65-70.
19. Minokoshi, Y., Kim, Y. B., Peroni, O. D., Fryer, L. G., Muller, C., Carling, D. & Kahn, B. B. (2002) Nature 415, 339-343.
20. Napolitano, L. & Gagne, H. T. (1963) Anat. Rec. 147, 273-280.
21. Lehman, J. J., Barger, P. M., Kovacs, A., Saffitz, J. E., Medeiros, D. M. & Kelly, D. P. (2000) J. Clin. Invest. 106, 847-856.
22. Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M. & Spiegelman, B. M. (1998) Cell 92, 829-839.
23. Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C. & Spiegelman, B. M. (1999) Cell 98, 115-124.
24. Tiraby, S., Tavernier, G., Lefort, C., Larrcuy, D., Bouillaud, F., Ricquier, D. & Langin, D. (2003) J. Biol. Chem. 278, 33370-33376.
25. Abu-Elheiga, L., Oh, W., Kordari, P. & Wakil, S. J. (2003) Proc. Natl. Acad. Sci. USA 100, 10207-10212.
26. Rosenbaum, M., Murphy, E. M., Heymsfield, S. B., Matthews, D. E. & Leibel, R. L. (2002) J. Clin. Endocrinol. Metab. 87, 2391-2394.
27. Wang, Z.-W., Zhou, Y. T., Lee, Y., Higa, M., Kalra, S. & Unger, R. H. (1999) Biochem. Biophys. Res. Commun. 260, 653-657.