Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase

Journal of Biological Chemistry

Volumn 281, Issue 8, 2006, Pages 4779-4786

  Franco, María C ^a   Antico Arciuch, Valeria G ^a   Peralta, Jorge G ^a   Galli, Soledad ^a   Levisman, Damián ^a   López, Lidia M ^a   Romorini, Leonardo ^a   Poderoso, Juan J ^a   Carreras, María C ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; HORMONES; METABOLISM; NEUROLOGY; OXIDES; PROTEINS; RNA;

HYPOTHYROID; MITOCHONDRIA; MITOCHONDRIAL COMPLEX I; NEURONAL NITRIC-OXIDE SYNTHASE;

NITRIC ACID;

3,3',5' TRIIODOTHYRONINE; CYCLIN D1; LIVER ENZYME; MESSENGER RNA; MITOCHONDRIAL COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE ALPHA; NITRIC OXIDE; OXIDOREDUCTASE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); THIAMAZOLE; THYROTROPIN; TYROSINE; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN 90; ISOPROTEIN; NITRIC OXIDE SYNTHASE; OXIDIZING AGENT; OXYGEN; PEROXYNITROUS ACID; THYROID HORMONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL METABOLIC RATE; CELL COMMUNICATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LOCALIZATION; HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; MALE; MITOCHONDRIAL RESPIRATION; NITRATION; NONHUMAN; OXYGEN CONSUMPTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL FRACTIONATION; CHEMICAL MODEL; CHEMISTRY; CYTOSOL; ELECTRON; ENZYMOLOGY; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; IMMUNOPRECIPITATION; LIVER; LIVER MITOCHONDRION; METABOLISM; MITOCHONDRION; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

ANIMALS; CYCLIN D1; CYTOSOL; ELECTRON TRANSPORT COMPLEX I; ELECTRONS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HSP90 HEAT-SHOCK PROTEINS; HYPOTHYROIDISM; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, IMMUNOELECTRON; MITOCHONDRIA; MITOCHONDRIA, LIVER; MODELS, CHEMICAL; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; OXIDANTS; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEROXYNITROUS ACID; PHENOTYPE; PROTEIN ISOFORMS; PROTEIN TRANSPORT; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; THYROID HORMONES; TRANSCRIPTION, GENETIC;

EID: 33646186367     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M512080200     Document Type: Article

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