Non-substituted N-heteroaromatic selenosemicarbazone metal complexes induce apoptosis in cancer cells via activation of mitochondrial pathway

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 3734-3747

  Srdić Rajić, Tatjana ^a   Zec, Manja ^a   Todorović, Tamara ^b   Anelković, Katarina ^b   Radulović, Siniša ^a  

^a INSTITUTE FOR ONCOLOGY AND RADIOLOGY OF SERBIA   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Antiproliferative activity; Apoptosis; Selenosemicarbazone; Zn(II), Ni(II), and Cd(II) complexes

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; CADMIUM; CASPASE 3; CISPLATIN; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE; NICKEL; PROTEIN BAX; PROTEIN P53; PROTEIN P73; ZINC;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; MICROVASCULAR ENDOTHELIAL CELL; MITOCHONDRION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CYTOCHROMES C; HUMANS; MEMBRANE LIPIDS; MEMBRANE POTENTIALS; METALS; MITOCHONDRIA; NEOPLASMS; SELENIUM; SEMICARBAZONES;

EID: 80052960393     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.05.039     Document Type: Article

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