Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction in intracellular drug accumulation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1743, Issue 3, 2005, Pages 269-279

  Amrán, Donna ^a   Sancho, Patricia ^a   Fernández, Carlos ^a   Esteban, Diego ^b   Ramos, Adrián M ^a   De Blas, Elena ^a   Gómez, Milagros ^b   Palacios, María A ^b   Aller, Patricio ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Apoptosis; Cisplatin; Drug accumulation; ERK inhibitor; Glutathione; Myeloid cell

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ARSENIC TRIOXIDE; BUTHIONINE SULFOXIMINE; CAMPTOTHECIN; CISPLATIN; ETOPOSIDE; GLUTATHIONE ETHYL ESTER; GLUTATHIONE REDUCTASE; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG TRANSPORT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; LEUKEMIA CELL; MACROPHAGE; MONOCYTIC LEUKEMIA; MYELOID LEUKEMIA; PRIORITY JOURNAL; TREATMENT FAILURE;

EID: 17444386342     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2004.10.009     Document Type: Article

References (36)

1. J.C. Ameisen On the origin, evolution, and nature of programmed cell death: a timeline of four billion years Cell Death Differ. 9 2002 367 393
2. L.A. Tibbles, and J.R. Woodgett The stress activated protein kinase pathways Cell. Mol. Life Sci. 55 1999 1230 1254
3. T.G. Cross, D. Scheel-Toellner, N.V. Henriquez, E. Deacon, M. Salmon, and J.M. Lord Serine/threonine protein kinases and apoptosis Exp. Cell Res. 256 2000 34 41
4. R.S. Go, and A.A. Adjei Review of the comparative pharmacology and clinical activity of cisplatin and carboplatin J. Clin. Oncol. 17 1999 409 422
5. E.R. Jamieson, and S.J. Lippard Structure, recognition and processing of cisplatin-DNA adducts Chem. Rev. 99 1999 2467 2498
6. A. Troyano, C. Fernández, P. Sancho, E. de Blas, and P. Aller Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation J. Biol. Chem. 276 2001 47107 47115
7. Z.H. Siddik Cisplatin: mode of cytotoxic action and molecular basis of resistance Oncogene 22 2003 7265 7279
8. J. Hayakawa, M. Ohmichi, H. Kurachi, H. Ikegami, A. Kimura, T. Matsuoka, H. Jikihara, D. Mercola, and Y. Murata Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line J. Biol. Chem. 274 1999 31648 31654
9. D.L. Persons, E.M. Yazlovitskaya, W. Cui, and J.C. Pelling Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin Clin. Cancer Res. 5 1999 1007 1014
10. A. Mandic, K. Viktorsson, T. Heiden, J. Hansson, and M.C. Shoshan The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis Melanoma Res. 11 2001 11 19
11. X. Wang, J.L. Martindale, and N.J. Holbrook Requirement for ERK activation in cisplatin-induced apoptosis J. Biol. Chem. 275 2000 39435 39443
12. P.Y. Yeh, S.E. Chuang, K.H. Yeh, Y.C. Song, C.K. Ea, and A.L. Cheng Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signalling pathway partly via enhancement of anticancer drug-induced NFκB activation Biochem. Pharmacol. 63 2002 1423 1430
13. W. Woessmann, X. Chen, and A. Borkhardt Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines Cancer Chemother. Pharmacol. 50 2002 397 404
14. A. Troyano, P. Sancho, C. Fernández, E. de Blas, P. Bernardi, and P. Aller The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells Cell Death Differ. 10 2003 889 898
15. K. Zhang, M. Chew, E.B. Yang, K.P. Wong, and P. Mack Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms Mol. Pharmacol. 59 2001 837 843
16. C. Fernández, A.M. Ramos, P. Sancho, D. Amrán, E. de Blas, and P. Aller 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione J. Biol. Chem. 279 2004 3877 3884
17. C. Sudström, and K. Nilsson Establishment and characterization of a human histiocytic lymphoma cell line (U-937) Int. J. Cancer 17 1976 565 577
18. S. Tsuchiya, M. Yamabe, Y. Yamaguchi, Y. Kobayashi, T. Konno, and K. Tada Establishment and characterization of a human acute monocytic leukemia cell line (THP-1) Int. J. Cancer 26 1980 171 176
19. S. Collins, R. Gallo, and R. Gallagher Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture Nature 270 1977 347 349
20. M. Lanotte, V. Martin-Thouvenin, S. Najman, P. Balerini, F. Valensi, and R. Berger NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3) Blood 77 1991 1080 1086
21. W.C. Raschke, S. Baird, P. Ralph, and I. Nakoinz Functional macrophage cell lines transformed by Abelson leukemia virus Cell 15 1978 261 267
22. J.E. De Larco, and G.J. Todaro Epithelioid and fibroblastic rat kidney cell clones: epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation J. Cell. Physiol. 94 1978 335 342
23. C.P. LeBel, H. Ischiropoulos, and S.C. Bondy Evaluation of the probe 2′,7′ dichlorofluorescein as an indicator of reactive oxygen species formation and oxidative stress Chem. Res. Toxicol. 5 1992 227 231
24. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 855
25. A. Galán, M.L. García-Bermejo, A. Troyano, N.E. Vilaboa, E. de Blas, M.G. Kazanietz, and P. Aller Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells J. Biol. Chem. 275 2000 11418 11424
26. A. Ballester, C. Pérez, P. Aller, and F. Mata Differentiation of U-937 promonocytic cells with mitomycin c or cis-diamminedichloroplatinum II Int. J. Cancer 65 1996 791 795
27. D.T. Dudley, L. Pang, S.J. Decker, A.J. Bridges, and A.R. Saltiel A synthetic inhibitor of the mitogen-activated protein kinase cascade Proc. Natl. Acad. Sci. U. S. A. 92 1995 7686 7689
28. M.H. Favata, K.I. Horiuchi, E.J. Manos, A.J. Daulerio, D.A. Stradley, W.S. Feeser, D.E. Van Dyk, W.J. Pitts, R.A. Earl, F. Hobbs, R.A. Copeland, R.L. Magolda, P.A. Scherle, and J.M. Trzaskos Identification of a novel inhibitor of mitogen-activated protein kinase kinase J. Biol. Chem. 273 1998 18623 18632
29. S.A. Susin, N. Zamzami, and G. Kroemer Mitochondria and regulators of apoptosis: doubt no more Biochim. Biophys. Acta 1366 1998 151 165
30. D. Toullec, P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, F. Loriolle, L. Duhamel, D. Charon, and J. Kirilovski The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C J. Biol. Chem. 266 1991 15771 15781
31. G. Filomeni, G. Rotilio, and M.R. Ciriolo Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p-38 MAP kinase pathway FASEB J. 17 2003 64 66
32. H.H. Bailey l-SR-buthionine sulfoximine: historical development and clinical issues Chem.-Biol. Interact. 111-112 1998 239 254
33. G. Speelmans, R.W. Staffhorst, K. Versluis, J. Reedijk, and B. de Kruijff Cisplatin complexes with phosphatidylserine in membranes Biochemistry 36 1997 10545 10550
34. M. Suwalsky, P. Hernandez, F. Villena, and C.P. Sotomayor The anticancer drug cisplatin interacts with the human erythrocyte membrane Z. Naturforsch., C 55 2000 461 466
35. M. Benhar, D. Engelberg, and A. Levitzki Cisplatin-induced activation of the EGF receptor Oncogene 21 2002 8723 8731
36. A. Basu, and R.W. Evans Comparison of the effects of growth factors and protein kinase c activators on cellular sensitivity to cis- diamminedichloroplatinum(II) Int. J. Cancer 58 1994 587 591