메뉴 건너뛰기




Volumn 64, Issue 1, 2004, Pages 329-336

F16, a Mitochondriotoxic Compound, Triggers Apoptosis or Necrosis Depending on the Genetic Background of the Target Carcinoma Cell

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; ETOPOSIDE; F 16; PROTEIN BCL 2; STAUROSPORINE; THAPSIGARGIN; TIRON; UNCLASSIFIED DRUG; ZVAD FMK;

EID: 1642494810     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-0899     Document Type: Article
Times cited : (65)

References (45)
  • 1
    • 0036654694 scopus 로고    scopus 로고
    • A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth
    • Fantin, V. R., Berardi, M. J., Scorrano, L., Korsmeyer, S. J., and Leder, P. A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth. Cancer Cell, 2: 29-42, 2002.
    • (2002) Cancer Cell , vol.2 , pp. 29-42
    • Fantin, V.R.1    Berardi, M.J.2    Scorrano, L.3    Korsmeyer, S.J.4    Leder, P.5
  • 2
    • 0024148694 scopus 로고
    • Mitochondrial membrane potential in living cells
    • Chen, L. B. Mitochondrial membrane potential in living cells. Annu. Rev. Cell Biol., 4: 155-181, 1988.
    • (1988) Annu. Rev. Cell Biol. , vol.4 , pp. 155-181
    • Chen, L.B.1
  • 3
    • 0035797118 scopus 로고    scopus 로고
    • Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells
    • Modica-Napolitano, J. S., and Aprille, J. R. Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells. Adv. Drug Delivery Rev., 49: 63-70, 2001.
    • (2001) Adv. Drug Delivery Rev. , vol.49 , pp. 63-70
    • Modica-Napolitano, J.S.1    Aprille, J.R.2
  • 4
    • 0033568486 scopus 로고    scopus 로고
    • Mitochondria and cell death: Mechanistic aspects and methodological issues
    • Bernardi, P., Scorrano, L., Colonna, R., Petronilli, V., and Di Lisa, F. Mitochondria and cell death: mechanistic aspects and methodological issues. Eur. J. Biochem., 264: 687-701, 1999.
    • (1999) Eur. J. Biochem. , vol.264 , pp. 687-701
    • Bernardi, P.1    Scorrano, L.2    Colonna, R.3    Petronilli, V.4    Di Lisa, F.5
  • 5
    • 0036308059 scopus 로고    scopus 로고
    • Mitochondria, the killer organelles and their weapons
    • Ravagnan, L., Roumier, T., and Kroemer, G. Mitochondria, the killer organelles and their weapons. J. Cell. Physiol., 192: 131-137, 2002.
    • (2002) J. Cell. Physiol. , vol.192 , pp. 131-137
    • Ravagnan, L.1    Roumier, T.2    Kroemer, G.3
  • 6
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory, S., and Adams, J. M. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer, 2: 647-656, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 7
    • 0033564103 scopus 로고    scopus 로고
    • Dead or dying: Necrosis versus apoptosis in caspase-deficient human renal cell carcinoma
    • Kolenko, V., Uzzo, R. G., Bukowski, R., Bander, N. H., Novick, A. C., Hsi, E. D., and Finke, J. H. Dead or dying: necrosis versus apoptosis in caspase-deficient human renal cell carcinoma. Cancer Res., 59: 2838-2842, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2838-2842
    • Kolenko, V.1    Uzzo, R.G.2    Bukowski, R.3    Bander, N.H.4    Novick, A.C.5    Hsi, E.D.6    Finke, J.H.7
  • 11
    • 0036498865 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian cell death machinery
    • Joza, N., Kroemer, G., and Penninger, J. M. Genetic analysis of the mammalian cell death machinery. Trends Genet., 18: 142-149, 2002.
    • (2002) Trends Genet. , vol.18 , pp. 142-149
    • Joza, N.1    Kroemer, G.2    Penninger, J.M.3
  • 12
    • 0037459081 scopus 로고    scopus 로고
    • Mitochondria: Releasing power for life and unleashing the machineries of death
    • Newmeyer, D. D., and Ferguson-Miller, S. Mitochondria: releasing power for life and unleashing the machineries of death. Cell, 112: 481-490, 2003.
    • (2003) Cell , vol.112 , pp. 481-490
    • Newmeyer, D.D.1    Ferguson-Miller, S.2
  • 14
    • 0037071388 scopus 로고    scopus 로고
    • Dysregulation of apoptosis genes in hematopoietic malignancies
    • Kitada, S., Pedersen, I. M., Schimmer, A. D., and Reed, J. C. Dysregulation of apoptosis genes in hematopoietic malignancies. Oncogene, 21: 3459-3474, 2002.
    • (2002) Oncogene , vol.21 , pp. 3459-3474
    • Kitada, S.1    Pedersen, I.M.2    Schimmer, A.D.3    Reed, J.C.4
  • 15
    • 0032877668 scopus 로고    scopus 로고
    • Dysregulation of apoptosis in cancer
    • Reed, J. C. Dysregulation of apoptosis in cancer. J. Clin. Oncol., 17: 2941-2953, 1999.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2941-2953
    • Reed, J.C.1
  • 16
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross, A., McDonnell, J. M., and Korsmeyer, S. J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev., 13: 1899-1911, 1999.
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 17
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: A link between cancer genetics and chemotherapy
    • Johnstone, R. W., Ruefli, A. A., and Lowe, S. W. Apoptosis: a link between cancer genetics and chemotherapy. Cell, 108: 153-164, 2002.
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 18
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita, T., and Reed, J. C. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood, 81: 151-157, 1993.
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 20
    • 0032828118 scopus 로고    scopus 로고
    • BCL-2 and p53 expression in clinically localized prostate cancer predicts response to external beam radiotherapy
    • discussion 16-17
    • Scherr, D. S., Vaughan, E. D., Jr., Wei, J., Chung, M., Felsen, D., Allbright, R., and Knudsen, B. S. BCL-2 and p53 expression in clinically localized prostate cancer predicts response to external beam radiotherapy. J. Urol., 162: 12-16; discussion 16-17, 1999.
    • (1999) J. Urol. , vol.162 , pp. 12-16
    • Scherr, D.S.1    Vaughan Jr., E.D.2    Wei, J.3    Chung, M.4    Felsen, D.5    Allbright, R.6    Knudsen, B.S.7
  • 21
    • 0032127416 scopus 로고    scopus 로고
    • The central role of the mitochondrial megachannel in apoptosis: Evidence obtained with intact cells, isolated mitochondria, and purified protein complexes
    • Marzo, I., Brenner, C., and Kroemer, G. The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes. Biomed. Pharmacother., 52: 248-251, 1998.
    • (1998) Biomed. Pharmacother. , vol.52 , pp. 248-251
    • Marzo, I.1    Brenner, C.2    Kroemer, G.3
  • 22
  • 24
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science (Wash. DC), 275: 1132-1136, 1997.
    • (1997) Science (Wash. DC) , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 25
    • 0032558736 scopus 로고    scopus 로고
    • The oncogene heregulin induces apoptosis in breast epithelial cells and tumors
    • Weinstein, E. J., Grimm, S., and Leder, P. The oncogene heregulin induces apoptosis in breast epithelial cells and tumors. Oncogene, 17: 2107-2113, 1998.
    • (1998) Oncogene , vol.17 , pp. 2107-2113
    • Weinstein, E.J.1    Grimm, S.2    Leder, P.3
  • 26
    • 0035910057 scopus 로고    scopus 로고
    • Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK
    • Thomas, D. A., Scorrano, L., Putcha, G. V., Korsmeyer, S. J., and Ley, T. J. Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK. Proc. Nad. Acad. Sci. USA, 98: 14985-14990, 2001.
    • (2001) Proc. Nad. Acad. Sci. USA , vol.98 , pp. 14985-14990
    • Thomas, D.A.1    Scorrano, L.2    Putcha, G.V.3    Korsmeyer, S.J.4    Ley, T.J.5
  • 27
    • 0033562145 scopus 로고    scopus 로고
    • Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells
    • Thongphasuk, J., Oberley, L. W., and Oberley, T. D. Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells. Arch. Biochem. Biophys., 365: 317-327, 1999.
    • (1999) Arch. Biochem. Biophys. , vol.365 , pp. 317-327
    • Thongphasuk, J.1    Oberley, L.W.2    Oberley, T.D.3
  • 28
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
    • Leist, M., Single, B., Castoldi, A. F., Kuhnle, S., and Nicotera, P. Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med., 185: 1481-1486, 1997.
    • (1997) J. Exp. Med. , vol.185 , pp. 1481-1486
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 29
    • 0028999212 scopus 로고
    • On the effects of paraquat on isolated mitochondria: Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide
    • Costantini, P., Petronilli, V., Colonna, R., and Bernardi, P. On the effects of paraquat on isolated mitochondria: evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. Toxicology, 99: 77-88, 1995.
    • (1995) Toxicology , vol.99 , pp. 77-88
    • Costantini, P.1    Petronilli, V.2    Colonna, R.3    Bernardi, P.4
  • 30
    • 0031032294 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
    • Decaudin, D., Geley, S., Hirsch, T., Castedo, M., Marchetti, P., Macho, A., Kofler, R., and Kroemer, G. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res., 57: 62-67, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 62-67
    • Decaudin, D.1    Geley, S.2    Hirsch, T.3    Castedo, M.4    Marchetti, P.5    Macho, A.6    Kofler, R.7    Kroemer, G.8
  • 31
    • 0030795866 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death
    • Simonian, P. L., Grillot, D. A., and Nunez, G. Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death. Blood, 90: 1208-1216, 1997.
    • (1997) Blood , vol.90 , pp. 1208-1216
    • Simonian, P.L.1    Grillot, D.A.2    Nunez, G.3
  • 32
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer, G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med., 3: 614-620, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 34
    • 0034951169 scopus 로고    scopus 로고
    • Mitochondria, oxygen free radicals, and apoptosis
    • Raha, S., and Robinson, B. H. Mitochondria, oxygen free radicals, and apoptosis. Am. J. Med. Genet., 106: 62-70, 2001.
    • (2001) Am. J. Med. Genet. , vol.106 , pp. 62-70
    • Raha, S.1    Robinson, B.H.2
  • 36
    • 0030915587 scopus 로고    scopus 로고
    • Intracellular ATP levels determine cell death fate by apoptosis or necrosis
    • Eguchi, Y., Shimizu, S., and Tsujimoto, Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res., 57: 1835-1840, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1835-1840
    • Eguchi, Y.1    Shimizu, S.2    Tsujimoto, Y.3
  • 37
    • 0033043803 scopus 로고    scopus 로고
    • Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins
    • Meilhac, O., Escargueil-Blanc, I., Thiers, J. C., Salvayre, R., and Negre-Salvayre, A. Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins. FASEB J., 13: 485-494, 1999.
    • (1999) FASEB J. , vol.13 , pp. 485-494
    • Meilhac, O.1    Escargueil-Blanc, I.2    Thiers, J.C.3    Salvayre, R.4    Negre-Salvayre, A.5
  • 38
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer, G., Dallaporta, B., and Resche-Rigon, M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol., 60: 619-642, 1998.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 39
    • 0032404536 scopus 로고    scopus 로고
    • The central executioners of apoptosis: Caspases or mitochondria?
    • Green, D., and Kroemer, G. The central executioners of apoptosis: caspases or mitochondria?. Trends Cell Biol., 8: 267-271, 1998.
    • (1998) Trends Cell Biol. , vol.8 , pp. 267-271
    • Green, D.1    Kroemer, G.2
  • 40
    • 0036561908 scopus 로고    scopus 로고
    • Modelling the molecular circuitry of cancer
    • Hahn, W. C., and Weinberg, R. A. Modelling the molecular circuitry of cancer. Nat. Rev. Cancer, 2: 331-341, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 331-341
    • Hahn, W.C.1    Weinberg, R.A.2
  • 41
    • 0033047268 scopus 로고    scopus 로고
    • Apoptosis versus necrosis: Which should be the aim of cancer therapy?
    • Kiaris, H., and Schally, A. V. Apoptosis versus necrosis: which should be the aim of cancer therapy?. Proc. Soc. Exp. Biol. Med., 221: 87-88, 1999.
    • (1999) Proc. Soc. Exp. Biol. Med. , vol.221 , pp. 87-88
    • Kiaris, H.1    Schally, A.V.2
  • 43
    • 0036889436 scopus 로고    scopus 로고
    • Comparison of anthracycline-induced death of human leukemia cells: Programmed cell death versus necrosis
    • Dartsch, D. C., Schaefer, A., Boldt, S., Kolch, W., and Marquardt, H. Comparison of anthracycline-induced death of human leukemia cells: programmed cell death versus necrosis. Apoptosis, 7: 537-548, 2002.
    • (2002) Apoptosis , vol.7 , pp. 537-548
    • Dartsch, D.C.1    Schaefer, A.2    Boldt, S.3    Kolch, W.4    Marquardt, H.5
  • 44
    • 0033566932 scopus 로고    scopus 로고
    • Cutting edge: Differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities
    • Reiter, I., Krammer, B., and Schwamberger, G. Cutting edge: differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities. J. Immunol., 163: 1730-1732, 1999.
    • (1999) J. Immunol. , vol.163 , pp. 1730-1732
    • Reiter, I.1    Krammer, B.2    Schwamberger, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.